Author, as appears in the article.: Catassi C; Bai JC; Bonaz B; Bouma G; Calabrò A; Carroccio A; Castillejo G; Ciacci C; Cristofori F; Dolinsek J; Francavilla R; Elli L; Green P; Holtmeier W; Koehler P; Koletzko S; Meinhold C; Sanders D; Schumann M; Schuppan D; Ullrich R; Vécsei A; Volta U; Zevallos V; Sapone A; Fasano A
Department: Medicina i Cirurgia
URV's Author/s: Castillejo De Villasante, Gemma
Keywords: Wheat allergy Gluten-related disorders Gluten-free diet Gluten sensitivity Celiac disease
Abstract: Non Celiac Gluten sensitivity (NCGS) was originally described in the 1980s and recently a re-discovered disorder characterized by intestinal and extra-intestinal symptoms related to the ingestion of gluten-containing food, in subjects that are not affected with either celiac disease (CD) or wheat allergy (WA). Although NCGS frequency is still unclear, epidemiological data have been generated that can help establishing the magnitude of the problem. Clinical studies further defined the identity of NCGS and its implications in human disease. An overlap between the irritable bowel syndrome (IBS) and NCGS has been detected, requiring even more stringent diagnostic criteria. Several studies suggested a relationship between NCGS and neuropsychiatric disorders, particularly autism and schizophrenia. The first case reports of NCGS in children have been described. Lack of biomarkers is still a major limitation of clinical studies, making it difficult to differentiate NCGS from other gluten related disorders. Recent studies raised the possibility that, beside gluten, wheat amylase-trypsin inhibitors and low-fermentable, poorly-absorbed, short-chain carbohydrates can contribute to symptoms (at least those related to IBS) experienced by NCGS patients. In this paper we report the major advances and current trends on NCGS. © 2013 by the authors; licensee MDPI, Basel, Switzerland.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 20726643
Author's mail: gemma.castillejo@urv.cat
Record's date: 2023-02-22
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2072-6643/5/10/3839
Papper original source: Nutrients. 5 (10): 3839-3853
APA: Catassi C; Bai JC; Bonaz B; Bouma G; Calabrò A; Carroccio A; Castillejo G; Ciacci C; Cristofori F; Dolinsek J; Francavilla R; Elli L; Green P; Holtmei (2013). Non-celiac gluten sensitivity: The new frontier of gluten related disorders. Nutrients, 5(10), 3839-3853. DOI: 10.3390/nu5103839
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.3390/nu5103839
Entity: Universitat Rovira i Virgili
Journal publication year: 2013
Publication Type: Journal Publications