Author, as appears in the article.: Guasch-Ferré M; Merino J; Sun Q; Fitó M; Salas-Salvadó J
Department: Bioquímica i Biotecnologia
URV's Author/s: MERINO RIBAS, JORDI / Salas Salvadó, Jorge
Keywords: Olive oil Newtonian liquids Insulin Hamiltonians Fluid dynamics Flavonoids
Abstract: © 2017 Marta Guasch-Ferré et al. Dietary polyphenols come mainly from plant-based foods including fruits, vegetables, whole grains, coffee, tea, and nuts. Polyphenols may influence glycemia and type 2 diabetes (T2D) through different mechanisms, such as promoting the uptake of glucose in tissues, and therefore improving insulin sensitivity. This review aims to summarize the evidence from clinical trials and observational prospective studies linking dietary polyphenols to prediabetes and T2D, with a focus on polyphenol-rich foods characteristic of the Mediterranean diet. We aimed to describe the metabolic biomarkers related to polyphenol intake and genotype-polyphenol interactions modulating the effects on T2D. Intakes of polyphenols, especially flavan-3-ols, and their food sources have demonstrated beneficial effects on insulin resistance and other cardiometabolic risk factors. Several prospective studies have shown inverse associations between polyphenol intake and T2D. The Mediterranean diet and its key components, olive oil, nuts, and red wine, have been inversely associated with insulin resistance and T2D. To some extent, these associations may be attributed to the high amount of polyphenols and bioactive compounds in typical foods conforming this traditional dietary pattern. Few studies have suggested that genetic predisposition can modulate the relationship between polyphenols and T2D risk. In conclusion, the intake of polyphenols may be beneficial for both insulin resistance and T2D risk.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Odontología Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Matemática / probabilidade e estatística Interdisciplinar General medicine Farmacia Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Cell biology Biotecnología Biodiversidade Biochemistry Aging
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 19420900
Author's mail: jordi.salas@urv.cat
Author identifier: 0000-0003-2700-7459
Record's date: 2023-02-19
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.hindawi.com/journals/omcl/2017/6723931/
Papper original source: Oxidative Medicine And Cellular Longevity. 2017 6723931-
APA: Guasch-Ferré M; Merino J; Sun Q; Fitó M; Salas-Salvadó J (2017). Dietary Polyphenols, Mediterranean Diet, Prediabetes, and Type 2 Diabetes: A Narrative Review of the Evidence. Oxidative Medicine And Cellular Longevity, 2017(), 6723931-. DOI: 10.1155/2017/6723931
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.1155/2017/6723931
Entity: Universitat Rovira i Virgili
Journal publication year: 2017
Publication Type: Journal Publications