Author, as appears in the article.: Royes J; Ni S; Farré A; La Cascia E; Carbó JJ; Cuenca AB; Maseras F; Fernández E
Department: Química Física i Inorgànica
URV's Author/s: Carbó Martin, Jorge Juan / Fernández Gutiérrez, Maria Elena / Fernández López, Elena / ROYES BUISAN, JORDI
Keywords: Spiroheterocyclic structures Dft study Borylative cyclization
Abstract: © 2018 American Chemical Society. The synthesis of spiroheterocyclic structures with a pendant methylene boronate substituent has been accomplished to promote further functionalization. A Cu-catalyzed borylative ring closing C-C coupling of an alkenyl halide is the key step toward the synthesis of [m.n]-spirocycles (m,n = 3-5). Computational studies on the mechanism reproduced all the experimental trends and explain the enhanced reactivity of systems leading to strained smaller rings. The optimized protocol also gives access to dispirocycle scaffolds, fully characterized by X-ray diffraction.
Thematic Areas: Química Materiais Interdisciplinar General chemistry Engenharias ii Ciências agrárias i Chemistry, physical Chemistry (miscellaneous) Chemistry (all) Catalysis Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 21555435
Author's mail: j.carbo@urv.cat mariaelena.fernandez@urv.cat
Author identifier: 0000-0002-3945-6721 0000-0001-9025-1791
Record's date: 2024-10-12
Papper version: info:eu-repo/semantics/acceptedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Acs Catalysis. 8 (4): 2833-2838
APA: Royes J; Ni S; Farré A; La Cascia E; Carbó JJ; Cuenca AB; Maseras F; Fernández E (2018). Copper-Catalyzed Borylative Ring Closing C-C Coupling toward Spiro- and Dispiroheterocycles. Acs Catalysis, 8(4), 2833-2838. DOI: 10.1021/acscatal.8b00257
Entity: Universitat Rovira i Virgili
Journal publication year: 2018
Publication Type: Journal Publications
Repositori URV