Articles producció científica> Enginyeria Química

Ln complexes as double faced agents: Study of antibacterial and antifungal activity

  • Identification data

    Identifier: imarina:6389636
    Authors:
    Cota IMarturano VTylkowski B
    Abstract:
    © 2019 Elsevier B.V. According to World Health Organization (WHO) infectious diseases are spreading faster and emerging more quickly than ever before. Due to the increasing incidents related with new and reemerging infectious diseases, discovery and development of new antimicrobial compounds with diverse structures and action mechanism is urgently needed. The antibacterial effects of lanthanides (Ln) have been studied since the 19th century and have been employed since then with more or less success in treatment of various diseases. This review gathers together all the studies dealing with the antimicrobial activity of Ln(III) complexes published until now. Overall, it was discovered that the antimicrobial activity of the Ln complexes is greater than the activity of the free ligand (L), indicating that the complexation with the Ln enhances the activity of the L. In some cases Ln complexes exhibit antimicrobial activity similar or even better than the activity of standard antimicrobial agents. These results are encouraging, Ln complexes representing a possible alternative to antimicrobial agents used currently.
  • Others:

    Author, as appears in the article.: Cota I; Marturano V; Tylkowski B
    Department: Enginyeria Química
    URV's Author/s: COTA, IULIANA MARIA / Tylkowski, Bartosz
    Keywords: Schiff base Ln(iii) complexes Complexation theory Antifungal activity Antibacterial activity
    Abstract: © 2019 Elsevier B.V. According to World Health Organization (WHO) infectious diseases are spreading faster and emerging more quickly than ever before. Due to the increasing incidents related with new and reemerging infectious diseases, discovery and development of new antimicrobial compounds with diverse structures and action mechanism is urgently needed. The antibacterial effects of lanthanides (Ln) have been studied since the 19th century and have been employed since then with more or less success in treatment of various diseases. This review gathers together all the studies dealing with the antimicrobial activity of Ln(III) complexes published until now. Overall, it was discovered that the antimicrobial activity of the Ln complexes is greater than the activity of the free ligand (L), indicating that the complexation with the Ln enhances the activity of the L. In some cases Ln complexes exhibit antimicrobial activity similar or even better than the activity of standard antimicrobial agents. These results are encouraging, Ln complexes representing a possible alternative to antimicrobial agents used currently.
    Thematic Areas: Química Physical and theoretical chemistry Medicina ii Materials chemistry Materiais Interdisciplinar Inorganic chemistry General chemistry Farmacia Engenharias iv Ciências biológicas ii Chemistry, inorganic & nuclear Chemistry (miscellaneous) Chemistry (all) Biotecnología Astronomia / física
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 00108545
    Author's mail: bartosz.tylkowski@urv.cat
    Author identifier: 0000-0002-4163-0178
    Record's date: 2023-07-31
    Papper version: info:eu-repo/semantics/acceptedVersion
    Link to the original source: https://www.sciencedirect.com/science/article/abs/pii/S0010854519301791
    Papper original source: Coordination Chemistry Reviews. 396 49-71
    APA: Cota I; Marturano V; Tylkowski B (2019). Ln complexes as double faced agents: Study of antibacterial and antifungal activity. Coordination Chemistry Reviews, 396(), 49-71. DOI: 10.1016/j.ccr.2019.05.019
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1016/j.ccr.2019.05.019
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2019
    Publication Type: Journal Publications
  • Keywords:

    Chemistry (Miscellaneous),Chemistry, Inorganic & Nuclear,Inorganic Chemistry,Materials Chemistry,Physical and Theoretical Chemistry
    Schiff base
    Ln(iii) complexes
    Complexation theory
    Antifungal activity
    Antibacterial activity
    Química
    Physical and theoretical chemistry
    Medicina ii
    Materials chemistry
    Materiais
    Interdisciplinar
    Inorganic chemistry
    General chemistry
    Farmacia
    Engenharias iv
    Ciências biológicas ii
    Chemistry, inorganic & nuclear
    Chemistry (miscellaneous)
    Chemistry (all)
    Biotecnología
    Astronomia / física
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