Articles producció científica> Ciències Mèdiques Bàsiques

Biomonitoring of co-exposure to bisphenols by consumers of canned foodstuffs

  • Identification data

    Identifier: imarina:6389882
    Authors:
    González NMarquès MCunha SCFernandes JODomingo JLNadal M
    Abstract:
    © 2020 The Authors For non-occupationally exposed adults, dietary intake is the main route of exposure to bisphenols (BPs), with canned foodstuffs playing a key role. This study was aimed at biomonitoring bisphenol A (BPA) and 5 more BP analogues (BPB, BPE, BPF, BPAF and BPZ) in spot urine and blood samples of a cohort of adults, who followed a diet based on a high consumption of canned food. To the best of our knowledge, this is the first study aimed at assessing the co-exposure of BP analogues in food and biological samples after a two-day duplicate diet study. The estimated total dietary exposure was 0.37 and 0.045 µg/kg body weight/day, for the canned-diet and control groups, respectively. BPA was the compound with the highest concentration in urine in comparison with the values of the remaining BP analogues. A high detection rate of BPA was noted in urine for both groups, 96% for the canned-diet group and 90% for the control group, while in blood it could be only quantified in 6% of the samples. The identification of other analogues was hardly related to diet, so it could be the result of other potential exposure sources, such as personal care products (PCPs) or air inhalation. After 2 days, the excretion of BPA was considerably higher in the canned-diet group subjects than those in the control group (7.02 vs. 1.89 µg/day), confirming that diet and canned foodstuffs are the main route of exposure to BPA. Anyhow, the temporary tolerable daily intake (t-TDI) established by the EFSA was not exceeded, even by those consumers with a diet rich in canned food. Moreover, spot urine samples provided accurate information about exposure and excretion of BPA, being the 4 h, instead of 24 h, the optimal sampling interval, when the collection of spot urine samples is not possibl
  • Others:

    Author, as appears in the article.: González N; Marquès M; Cunha SC; Fernandes JO; Domingo JL; Nadal M
    Department: Ciències Mèdiques Bàsiques
    URV's Author/s: Domingo Roig, José Luis / Gonzalez Paradell, Nieves / Marquès Bueno, Montserrat / Nadal Lomas, Martí
    Keywords: Urine Thermal paper Taihu lake Prenatal exposure Occupational-exposure Mass-spectrometry Human urine Human health Human exposure Endocrine-disrupting chemicals Duplicate diet Bpa Bisphenol analogues Biomonitoring A bpa duplicate diet bpa bisphenol analogues biomonitoring
    Abstract: © 2020 The Authors For non-occupationally exposed adults, dietary intake is the main route of exposure to bisphenols (BPs), with canned foodstuffs playing a key role. This study was aimed at biomonitoring bisphenol A (BPA) and 5 more BP analogues (BPB, BPE, BPF, BPAF and BPZ) in spot urine and blood samples of a cohort of adults, who followed a diet based on a high consumption of canned food. To the best of our knowledge, this is the first study aimed at assessing the co-exposure of BP analogues in food and biological samples after a two-day duplicate diet study. The estimated total dietary exposure was 0.37 and 0.045 µg/kg body weight/day, for the canned-diet and control groups, respectively. BPA was the compound with the highest concentration in urine in comparison with the values of the remaining BP analogues. A high detection rate of BPA was noted in urine for both groups, 96% for the canned-diet group and 90% for the control group, while in blood it could be only quantified in 6% of the samples. The identification of other analogues was hardly related to diet, so it could be the result of other potential exposure sources, such as personal care products (PCPs) or air inhalation. After 2 days, the excretion of BPA was considerably higher in the canned-diet group subjects than those in the control group (7.02 vs. 1.89 µg/day), confirming that diet and canned foodstuffs are the main route of exposure to BPA. Anyhow, the temporary tolerable daily intake (t-TDI) established by the EFSA was not exceeded, even by those consumers with a diet rich in canned food. Moreover, spot urine samples provided accurate information about exposure and excretion of BPA, being the 4 h, instead of 24 h, the optimal sampling interval, when the collection of spot urine samples is not possible.
    Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Medicina iii Medicina ii Medicina i Interdisciplinar Geociências General medicine General environmental science Farmacia Environmental sciences Environmental science (miscellaneous) Environmental science (all) Engenharias iv Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Biotecnología Biodiversidade Astronomia / física Administração pública e de empresas, ciências contábeis e turismo
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 01604120
    Author's mail: marti.nadal@urv.cat nieves.gonzalez@urv.cat montserrat.marques@urv.cat marti.nadal@urv.cat joseluis.domingo@urv.cat
    Author identifier: 0000-0002-0217-4827 0000-0003-4134-016X 0000-0001-6302-8578 0000-0002-0217-4827 0000-0001-6647-9470
    Record's date: 2024-06-15
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.sciencedirect.com/science/article/pii/S0160412020306954
    Papper original source: Environment International. 140 (UNSP 105760): 105760-
    APA: González N; Marquès M; Cunha SC; Fernandes JO; Domingo JL; Nadal M (2020). Biomonitoring of co-exposure to bisphenols by consumers of canned foodstuffs. Environment International, 140(UNSP 105760), 105760-. DOI: 10.1016/j.envint.2020.105760
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1016/j.envint.2020.105760
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2020
    Publication Type: Journal Publications
  • Keywords:

    Environmental Science (Miscellaneous),Environmental Sciences
    Urine
    Thermal paper
    Taihu lake
    Prenatal exposure
    Occupational-exposure
    Mass-spectrometry
    Human urine
    Human health
    Human exposure
    Endocrine-disrupting chemicals
    Duplicate diet
    Bpa
    Bisphenol analogues
    Biomonitoring
    A bpa
    duplicate diet
    bpa
    bisphenol analogues
    biomonitoring
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    Geociências
    General medicine
    General environmental science
    Farmacia
    Environmental sciences
    Environmental science (miscellaneous)
    Environmental science (all)
    Engenharias iv
    Engenharias ii
    Engenharias i
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Biotecnología
    Biodiversidade
    Astronomia / física
    Administração pública e de empresas, ciências contábeis e turismo
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