Author, as appears in the article.: Meritxell López; Angel Ríos; María Adoración Romaguera Bosch; Miguel Ángel Martínez González; Fernando Fernández Aranda; Jordi Salas Salvadó; Dolores Corella Piquer; Montserrat Fitó; Jesús Vioque Lopez; Ángel M Alonso Gómez; Edelys Crespo Oliva; José Alfredo Martínez Hernández; Lluís Serra Majem; Ramón Estruch Riba; Francisco José Tinahones Madueño; José Lapetra Peralta; Xavier Pintó Sala; Josep Antoni Tur Marí; Antonio García Ríos; Aurora Bueno Cavanillas; José Juan Gaforio; Pilar Matía Martín; Lidia Ángeles Daimiel Ruiz; Rubén Sánchez Rodríguez; Josep Vidal Tort; Enrique Sanz Martínez; Emilio Ros Rahola; Estefanía Toledo Atucha; Laura Barrubés; Rocío Barragán; Rafael de la Torre; Miquel Fiol; Sandra González Palacios; Carolina Sorto; María Victoria Martín Ruiz; María Angeles Zulet Alzórriz; Fátima Díaz Collado; Rosa Casas; José Carlos Fernández García; JM Santos-Lozano; Núria Mallorquí Bagué; Emma Argelich; Óscar Lecea; Indira Paz Graniel; José Vicente Sorlí Guerola; Aida Cuenca; Susana Munuera; María Vicenta Hernándis Marsán; Jessica Vaquero Luna; Miguel Ruiz-Canela López; Lucía Camacho Barcia; Susana Jiménez Murcia; Olga Castañer Niño; Aina Maria Yáñez Juan
Department: Bioquímica i Biotecnologia
URV's Author/s: Barrubés Piñol, Laura / Paz Graniel, Indira del Socorro / Salas Salvadó, Jorge
Keywords: Peripheral artery disease Mini-mental-state Metabolic syndrome Cross-sectional study Cognitive function Ankle-brachial index risk mortality metabolic syndrome impairment dementia cross-sectional study cognitive function atherosclerosis ankle-brachial index
Abstract: © 2020 Sociedad Española de Cardiología Introduction and objectives: The ankle-brachial index (ABI) is an indicator of peripheral artery disease (PAD). The aim of this study was to assess the association between PAD, measured with the ABI, and cognitive function in persons with overweight or obesity and metabolic syndrome. Methods: Cross-sectional study conducted with baseline data from the PREDIMED-Plus study, which included 4898 participants (after exclusion of those without ABI measurements) aged between 55 and 75 years, and with overweight or obesity and metabolic syndrome. At the baseline assessment, we measured the ABI with a standardized protocol and assessed the presence of other cardiovascular risk factors (eg, diabetes, dyslipidemia, hypertension). Cognitive function was evaluated using several tests validated for the Spanish population (mini-mental state examination [MMSE], phonological and semantic verbal fluency test, WAIS-III working memory index [WMI], parts A and B of the trail making test (TMT), and clock drawing test). Generalized linear models were used to assess the association between the ABI and cognitive function. Results: Among the participants, 3.4% had PAD defined as ABI ≤ 0.9, and 3.3% had arterial calcification defined as ABI ≥ 1.4. PAD was associated with age, systolic blood pressure and obesity indicators, while arterial calcification was also associated with obesity and diabetes. No significant associations were observed between cognitive function and ABI or PAD. Conclusions: In our sample, the presence of PAD increased with age, blood pressure, and obesity. No significant association was observed between ABI, PAD, or cognitive function.
Thematic Areas: Revistas de ciencias de la salud Medicine (miscellaneous) Medicine (all) Medicina ii Medicina i Interdisciplinar General medicine Cardiology and cardiovascular medicine Cardiac & cardiovascular systems
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 15792250
Author's mail: indiradelsocorro.paz@urv.cat jordi.salas@urv.cat indiradelsocorro.paz@urv.cat
Author identifier: 0000-0003-2700-7459
Record's date: 2023-02-19
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://www.sciencedirect.com/science/article/abs/pii/S0300893220303717?via%3Dihub#!
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Revista Espanola De Cardiologia. 74 (10): 846-853
APA: Meritxell López; Angel Ríos; María Adoración Romaguera Bosch; Miguel Ángel Martínez González; Fernando Fernández Aranda; Jordi Salas Salvadó; Dolores (2021). Association between ankle-brachial index and cognitive function in participants in the PREDIMED-Plus study: cross-sectional assessment. Revista Espanola De Cardiologia, 74(10), 846-853. DOI: 10.1016/j.recesp.2020.06.031
Article's DOI: 10.1016/j.recesp.2020.06.031
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications