Author, as appears in the article.: López, M; Ríos, A; Romaguera, D; Martínez-González, MA; Fernández-Aranda, F; Salas-Salvadó, J; Corella, D; Fitó, M; Vioque, J; Alonso-Gómez, AM; Crespo-Oliva, E; Martínez, JA; Serra-Majem, L; Estruch, R; Tinahones, FJ; Lapetra, J; Pintó, X; Tur, JA; García-Ríos, A; Bueno-Cavanillas, A; Gaforio, JJ; Matía-Martín, P; Daimiel, L; Sánchez-Rodríguez, R; Vidal, J; Sanz-Martínez, E; Ros, E; Toledo, E; Barrubés, L; Barragán, R; de la Torre, R; Fiol, M; González-Palacios, S; Sorto-Sánchez, C; Martín-Ruiz, MV; Zulet, MA; Díaz-Collado, F; Casas, R; Fernández-García, JC; Santos-Lozano, JM; Mallorqui-Bagué, N; Argelich, E; Lecea, O; Paz-Graniel, I; Sorli, JV; Cuenca, A; Munuera, S; Hernándis-Marsán, MV; Vaquero-Luna, J; Ruiz-Canela, M; Camacho-Barcia, L; Jiménez-Murcia, S; Castañer, O; Yáñez, AM
Department: Bioquímica i Biotecnologia
URV's Author/s: Barrubés Piñol, Laura / Paz Graniel, Indira del Socorro / Salas Salvadó, Jorge
Keywords: Peripheral artery disease Mini-mental-state Metabolic syndrome Cross-sectional study Cognitive function Ankle-brachial index risk mortality metabolic syndrome impairment dementia cross-sectional study cognitive function atherosclerosis ankle-brachial index
Abstract: © 2020 Sociedad Española de Cardiología Introduction and objectives: The ankle-brachial index (ABI) is an indicator of peripheral artery disease (PAD). The aim of this study was to assess the association between PAD, measured with the ABI, and cognitive function in persons with overweight or obesity and metabolic syndrome. Methods: Cross-sectional study conducted with baseline data from the PREDIMED-Plus study, which included 4898 participants (after exclusion of those without ABI measurements) aged between 55 and 75 years, and with overweight or obesity and metabolic syndrome. At the baseline assessment, we measured the ABI with a standardized protocol and assessed the presence of other cardiovascular risk factors (eg, diabetes, dyslipidemia, hypertension). Cognitive function was evaluated using several tests validated for the Spanish population (mini-mental state examination [MMSE], phonological and semantic verbal fluency test, WAIS-III working memory index [WMI], parts A and B of the trail making test (TMT), and clock drawing test). Generalized linear models were used to assess the association between the ABI and cognitive function. Results: Among the participants, 3.4% had PAD defined as ABI ≤ 0.9, and 3.3% had arterial calcification defined as ABI ≥ 1.4. PAD was associated with age, systolic blood pressure and obesity indicators, while arterial calcification was also associated with obesity and diabetes. No significant associations were observed between cognitive function and ABI or PAD. Conclusions: In our sample, the presence of PAD increased with age, blood pressure, and obesity. No significant association was observed between ABI, PAD, or cognitive function.
Thematic Areas: Revistas de ciencias de la salud Medicine (miscellaneous) Medicine (all) Medicina ii Medicina i Interdisciplinar General medicine Cardiology and cardiovascular medicine Cardiac & cardiovascular systems
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 15792250
Author's mail: jordi.salas@urv.cat indiradelsocorro.paz@urv.cat indiradelsocorro.paz@urv.cat
Author identifier: 0000-0003-2700-7459 0000-0002-3204-6877 0000-0002-3204-6877
Record's date: 2024-05-23
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://www.sciencedirect.com/science/article/abs/pii/S0300893220303717?via%3Dihub#!
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Revista Espanola De Cardiologia. 74 (10): 846-853
APA: López, M; Ríos, A; Romaguera, D; Martínez-González, MA; Fernández-Aranda, F; Salas-Salvadó, J; Corella, D; Fitó, M; Vioque, J; Alonso-Gómez, AM; Cresp (2021). Association between ankle-brachial index and cognitive function in participants in the PREDIMED-Plus study: cross-sectional assessment. Revista Espanola De Cardiologia, 74(10), 846-853. DOI: 10.1016/j.recesp.2020.06.031
Article's DOI: 10.1016/j.recesp.2020.06.031
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications
Repositori URV