Author, as appears in the article.: López-García E; Pérez-López C; Postigo C; Andreu V; Bijlsma L; González-Mariño I; Hernández F; Marcé RM; Montes R; Picó Y; Pocurull E; Rico A; Rodil R; Rosende M; Valcárcel Y; Zuloaga O; Quintana JB; López de Alda M

Department: Química Analítica i Química Orgànica

URV's Author/s: Marcé Recasens, Rosa Maria / Pocurull Aixala, Eva

Keywords: Trends Sewage epidemiology Metabolite Liquid chromatography-mass spectrometry Ethyl sulfate Ethanol Drugs Drinking Consumption patterns City Cities Biomarkers Alcohol abuse Abuse

Abstract: © 2020 Elsevier B.V. Background: In this study, an alternative and complementary method to those approaches currently used to estimate alcohol consumption by the population is described. This method, known as wastewater-based epidemiology (WBE), allows back-calculating the alcohol consumption rate in a given population from the concentrations of a selected biomarker measured in wastewater. Methods: Composite (24-h) wastewater samples were collected at the inlet of 17 wastewater treatment plants located in 13 Spanish cities for seven consecutive days in 2018. The sampled area covered 12.8% of the Spanish population. Wastewater samples were analyzed to determine the concentration of ethyl sulfate, the biomarker used to back-calculate alcohol consumption. Results: Alcohol consumption ranged from 4.5 to 46 mL/day/inhabitant. Differences in consumption were statistically significant among the investigated cities and between weekdays and weekends. WBE-derived estimates of alcohol consumption were comparable to those reported by its corresponding region in the Spanish National Health Survey in most cases. At the national level, comparable results were obtained between the WBE-derived annual consumption rate (5.7 ± 1.2 L ethanol per capita (aged 15+)) and that reported by the National Health Survey (4.7 L ethanol per capita (aged 15+)). Conclusions: This is the largest WBE study carried out to date in Spain to estimate alcohol consumption rates. It confirms that this approach is useful for establishing spatial and temporal patterns of alcohol consumption, which could contribute to the development of health care management plans and policies. Contrary to established methods, it allows obtaining information in a fast and relatively economical way.

Thematic Areas: Toxicology Substance abuse Saúde coletiva Psychiatry and mental health Psychiatry Psicología Pharmacology (medical) Pharmacology Nutrição Medicina iii Medicina ii Medicina i Matemática / probabilidade e estatística Interdisciplinar General medicine Ensino Engenharias iv Enfermagem Ciencias sociales Ciências biológicas ii Ciências biológicas i Ciência da computação Biotecnología

licence for use: https://creativecommons.org/licenses/by/3.0/es/

Author's mail: rosamaria.marce@urv.cat eva.pocurull@urv.cat

Author identifier: 0000-0002-5667-2899 0000-0001-5123-995X

Record's date: 2023-02-23

Papper version: info:eu-repo/semantics/acceptedVersion

Link to the original source: https://www.sciencedirect.com/science/article/abs/pii/S0376871620304063

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Drug And Alcohol Dependence. 215 (108241): 108241-

APA: López-García E; Pérez-López C; Postigo C; Andreu V; Bijlsma L; González-Mariño I; Hernández F; Marcé RM; Montes R; Picó Y; Pocurull E; Rico A; Rodil R (2020). Assessing alcohol consumption through wastewater-based epidemiology: Spain as a case study. Drug And Alcohol Dependence, 215(108241), 108241-. DOI: 10.1016/j.drugalcdep.2020.108241

Article's DOI: 10.1016/j.drugalcdep.2020.108241

Entity: Universitat Rovira i Virgili

Journal publication year: 2020

Publication Type: Journal Publications