Author, as appears in the article.: Castro-Quezada, Itandehui; Sanchez-Villegas, Almudena; Estruch, Ramon; Salas-Salvado, Jordi; Corella, Dolores; Schroeder, Helmut; Alvarez-Perez, Jacqueline; Dolores Ruiz-Lopez, Maria; Artacho, Reyes; Ros, Emilio; Covas, Maria-Isabel; Ruiz-Gutierrez, Valentina; Ruiz-Canela, Miguel; Buil-Cosiales, Pilar; Gomez-Gracia, Enrique; Lapetra, Jose; Pinto, Xavier; Aros, Fernando; Fiol, Miquel; Maria Lamuela-Raventos, Rosa; Angel Martinez-Gonzalez, Miguel; Serra-Majem, Lluis
Department: Bioquímica i Biotecnologia
URV's Author/s: Bulló Bonet, Mònica / Salas Salvadó, Jorge
Keywords: @infoAeu @residentesaeu @uroweb Etiqueta «#» Hashtag
Abstract: Different types of carbohydrates have diverse glycemic response, thus glycemic index (GI) and glycemic load (GL) are used to assess this variation. The impact of dietary GI and GL in all-cause mortality is unknown. The objective of this study was to estimate the association between dietary GI and GL and risk of all-cause mortality in the PREDIMED study.The PREDIMED study is a randomized nutritional intervention trial for primary cardiovascular prevention based on community-dwelling men and women at high risk of cardiovascular disease. Dietary information was collected at baseline and yearly using a validated 137-item food frequency questionnaire (FFQ). We assigned GI values of each item by a 5-step methodology, using the International Tables of GI and GL Values. Deaths were ascertained through contact with families and general practitioners, review of medical records and consultation of the National Death Index. Cox regression models were used to estimate multivariable-adjusted hazard ratios (HR) and their 95% CI for mortality, according to quartiles of energy-adjusted dietary GI/GL. To assess repeated measures of exposure, we updated GI and GL intakes from the yearly FFQs and used Cox models with time-dependent exposures.We followed 3,583 non-diabetic subjects (4.7 years of follow-up, 123 deaths). As compared to participants in the lowest quartile of baseline dietary GI, those in the highest quartile showed an increased risk of all-cause mortality [HR?=?2.15 (95% CI: 1.15-4.04); P for trend ?=?0.012]. In the repeated-measures analyses using as exposure the yearly updated information on GI, we observed a similar association. Dietary GL was associated with all-cause mortality only when subjects were younger than 75 years.High dietary GI was positively associated with all-cause mortality in elderly population at high cardiovascular risk.
Thematic Areas: Zootecnia / recursos pesqueiros Sociology Sociología Serviço social Saúde coletiva Química Psychology Psicología Planejamento urbano e regional / demografia Odontología Nutrição Multidisciplinary sciences Multidisciplinary Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Linguística e literatura Letras / linguística Interdisciplinary research in the social sciences Interdisciplinar Human geography and urban studies History & philosophy of science Historia Geografía Geociências General medicine General biochemistry,genetics and molecular biology General agricultural and biological sciences Farmacia Environmental studies Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Enfermagem Educação física Educação Economia Direito Demography Comunicação e informação Ciências sociais aplicadas i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência política e relações internacionais Ciência de alimentos Ciência da computação Biotecnología Biology Biodiversidade Biochemistry, genetics and molecular biology (miscellaneous) Astronomia / física Arquitetura, urbanismo e design Archaeology Antropologia / arqueologia Anthropology Agricultural and biological sciences (miscellaneous) Administração, ciências contábeis e turismo Administração pública e de empresas, ciências contábeis e turismo
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 19326203
Author's mail: monica.bullo@urv.cat jordi.salas@urv.cat
Author identifier: 0000-0002-0218-7046 0000-0003-2700-7459
Record's date: 2024-08-31
Papper version: info:eu-repo/semantics/publishedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Plos One. 9 (9): e107968-NA
APA: Castro-Quezada, Itandehui; Sanchez-Villegas, Almudena; Estruch, Ramon; Salas-Salvado, Jordi; Corella, Dolores; Schroeder, Helmut; Alvarez-Perez, Jacqu (2014). A High Dietary Glycemic Index Increases Total Mortality in a Mediterranean Population at High Cardiovascular Risk. Plos One, 9(9), e107968-NA. DOI: 10.1371/journal.pone.0107968
Entity: Universitat Rovira i Virgili
Journal publication year: 2014
Publication Type: Journal Publications