Author, as appears in the article.: Castro-Quezada, Itandehui; Sanchez-Villegas, Almudena; Estruch, Ramon; Salas-Salvado, Jordi; Corella, Dolores; Schroeder, Helmut; Alvarez-Perez, Jacqueline; Dolores Ruiz-Lopez, Maria; Artacho, Reyes; Ros, Emilio; Covas, Maria-Isabel; Ruiz-Gutierrez, Valentina; Ruiz-Canela, Miguel; Buil-Cosiales, Pilar; Gomez-Gracia, Enrique; Lapetra, Jose; Pinto, Xavier; Aros, Fernando; Fiol, Miquel; Maria Lamuela-Raventos, Rosa; Angel Martinez-Gonzalez, Miguel; Serra-Majem, Lluis
Department: Bioquímica i Biotecnologia
URV's Author/s: Bulló Bonet, Mònica / Salas Salvadó, Jorge
Keywords: @infoAeu @residentesaeu @uroweb Etiqueta «#» Hashtag
Abstract: Different types of carbohydrates have diverse glycemic response, thus glycemic index (GI) and glycemic load (GL) are used to assess this variation. The impact of dietary GI and GL in all-cause mortality is unknown. The objective of this study was to estimate the association between dietary GI and GL and risk of all-cause mortality in the PREDIMED study.The PREDIMED study is a randomized nutritional intervention trial for primary cardiovascular prevention based on community-dwelling men and women at high risk of cardiovascular disease. Dietary information was collected at baseline and yearly using a validated 137-item food frequency questionnaire (FFQ). We assigned GI values of each item by a 5-step methodology, using the International Tables of GI and GL Values. Deaths were ascertained through contact with families and general practitioners, review of medical records and consultation of the National Death Index. Cox regression models were used to estimate multivariable-adjusted hazard ratios (HR) and their 95% CI for mortality, according to quartiles of energy-adjusted dietary GI/GL. To assess repeated measures of exposure, we updated GI and GL intakes from the yearly FFQs and used Cox models with time-dependent exposures.We followed 3,583 non-diabetic subjects (4.7 years of follow-up, 123 deaths). As compared to participants in the lowest quartile of baseline dietary GI, those in the highest quartile showed an increased risk of all-cause mortality [HR?=?2.15 (95% CI: 1.15-4.04); P for trend ?=?0.012]. In the repeated-measures analyses using as exposure the yearly updated information on GI, we observed a similar association. Dietary GL was associated with all-cause mortality only when subjects were younger than 75 years.High dietary GI was positively associated with all-cause mortality in elderly population at high cardiovascular risk.
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licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 19326203
Author's mail: monica.bullo@urv.cat jordi.salas@urv.cat
Author identifier: 0000-0002-0218-7046 0000-0003-2700-7459
Record's date: 2024-08-31
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107968
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Plos One. 9 (9): e107968-NA
APA: Castro-Quezada, Itandehui; Sanchez-Villegas, Almudena; Estruch, Ramon; Salas-Salvado, Jordi; Corella, Dolores; Schroeder, Helmut; Alvarez-Perez, Jacqu (2014). A High Dietary Glycemic Index Increases Total Mortality in a Mediterranean Population at High Cardiovascular Risk. Plos One, 9(9), e107968-NA. DOI: 10.1371/journal.pone.0107968
Article's DOI: 10.1371/journal.pone.0107968
Entity: Universitat Rovira i Virgili
Journal publication year: 2014
Publication Type: Journal Publications
Repositori URV