Articles producció científica> Química Analítica i Química Orgànica

Paper-based Potentiometric Biosensor for Monitoring Galactose in Whole Blood

  • Identification data

    Identifier: imarina:8504701
    Authors:
    Bouri, MohamedZuaznabar-Gardona, Julio C.Novell, MartaBlondeau, PascalAndrade, Francisco J.
    Abstract:
    A filter paper sputtered with a layer of Pt and subsequently coated with a Nafion (R) membrane is used as working electrode. The mixed potential of the Pt electrode allows the detection of H2O2 generated by the oxidation of galactose in the presence of the galactose oxidase enzyme. This provides a simple and mediator-free approach method. The system shows sensitivity values of -62.8 +/- 9.4 mV/decade of galactose in the range from 0.3 to 31.6 mM, well within the clinical relevant range. MnO2 nanoparticles were added to decrease the interference from ascorbic acid so that validation of the sensor in whole blood samples was performed with good recovery.
  • Others:

    e-ISSN: 1521-4109
    Project code: CTQ2016-77128-R
    Keywords: Screen Potentiometry Paper-based platform Mno2 Mixed potential Glucose Galactosemia Electrodes Diagnosis Cell Biosensor
    Record's date: 2024-07-27
    Papper version: info:eu-repo/semantics/acceptedVersion
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Electroanalysis. 33 (1): 81-89
    APA: Bouri, Mohamed; Zuaznabar-Gardona, Julio C.; Novell, Marta; Blondeau, Pascal; Andrade, Francisco J.; (2021). Paper-based Potentiometric Biosensor for Monitoring Galactose in Whole Blood. Electroanalysis, 33(1), 81-89. DOI: 10.1002/elan.202060285
    Acronym: HOMESENS
    Publication Type: Journal Publications
    Author, as appears in the article.: Bouri, Mohamed; Zuaznabar-Gardona, Julio C.; Novell, Marta; Blondeau, Pascal; Andrade, Francisco J.;
    Department: Química Analítica i Química Orgànica
    Acronym 2: SMARTCHEM
    URV's Author/s: Andrade, Francisco Javier / Blondeau, Pascal Jean Claude Leon / NOVELL RECASENS, MARTA / ZUAZNABAR GARDONA, JULIO CÉSAR
    Abstract: A filter paper sputtered with a layer of Pt and subsequently coated with a Nafion (R) membrane is used as working electrode. The mixed potential of the Pt electrode allows the detection of H2O2 generated by the oxidation of galactose in the presence of the galactose oxidase enzyme. This provides a simple and mediator-free approach method. The system shows sensitivity values of -62.8 +/- 9.4 mV/decade of galactose in the range from 0.3 to 31.6 mM, well within the clinical relevant range. MnO2 nanoparticles were added to decrease the interference from ascorbic acid so that validation of the sensor in whole blood samples was performed with good recovery.
    Program founding action 2: Proyecto de I+D+i RTI Tipo B
    Thematic Areas: Saúde coletiva Química Psicología Medicina ii Medicina i Materiais Interdisciplinar Geociências Farmacia Engenharias iii Engenharias ii Electrochemistry Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Chemistry, analytical Biotecnología Biodiversidade Astronomia / física Analytical chemistry
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 1040-0397
    Author's mail: pascal.blondeau@urv.cat franciscojavier.andrade@urv.cat
    Author identifier: 0000-0003-1331-5055 0000-0003-1199-2837
    Project code 2: PID2019-106862RB-I00
    Founding program 2: Programa Estatal De Generación De Conocimiento Y Fortalecimiento Científico y Tecnológico Del Sistema De I+D+i y del Programa Estatal De I+D+i Orientada los Retos de la Sociedad (Agencia Estatal de Investigación - Ministerio de Ciencia e Innovación).
    Link to the original source: https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/ftr/10.1002/elan.202060285
    Funding program: Programa Estatal de Investigación, Desarrollo e Innovación Orientada a los Retos de la Sociedad (Agencia Estatal de Investigación - Ministerio de Economía, Industria y Competitividad)
    Article's DOI: 10.1002/elan.202060285
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Funding program action: Proyecto de I+D
  • Keywords:

    Analytical Chemistry,Chemistry, Analytical,Electrochemistry
    Screen
    Potentiometry
    Paper-based platform
    Mno2
    Mixed potential
    Glucose
    Galactosemia
    Electrodes
    Diagnosis
    Cell
    Biosensor
    Saúde coletiva
    Química
    Psicología
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Geociências
    Farmacia
    Engenharias iii
    Engenharias ii
    Electrochemistry
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Chemistry, analytical
    Biotecnología
    Biodiversidade
    Astronomia / física
    Analytical chemistry
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