Articles producció científicaQuímica Analítica i Química Orgànica

Paper-based Potentiometric Biosensor for Monitoring Galactose in Whole Blood

  • Identification data

    Identifier:  imarina:8504701
    Handle: https://hdl.handle.net/20.500.11797/imarina8504701
    Authors:  Bouri, Mohamed; Zuaznabar-Gardona, Julio C; Novell, Marta; Blondeau, Pascal; Andrade, Francisco J
    Abstract:
    A filter paper sputtered with a layer of Pt and subsequently coated with a Nafion (R) membrane is used as working electrode. The mixed potential of the Pt electrode allows the detection of H2O2 generated by the oxidation of galactose in the presence of the galactose oxidase enzyme. This provides a simple and mediator-free approach method. The system shows sensitivity values of -62.8 +/- 9.4 mV/decade of galactose in the range from 0.3 to 31.6 mM, well within the clinical relevant range. MnO2 nanoparticles were added to decrease the interference from ascorbic acid so that validation of the sensor in whole blood samples was performed with good recovery.

  • Others:

    Link to the original source: https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/ftr/10.1002/elan.202060285
    Paper original source: Electroanalysis. 33 (1): 81-89
    Entity: Universitat Rovira i Virgili
    Record's date: 2025-01-27
    URV's Author/s: Andrade, Francisco Javier / Blondeau, Pascal Jean Claude Leon / NOVELL RECASENS, MARTA / ZUAZNABAR GARDONA, JULIO CÉSAR
    Project code 2: PID2019-106862RB-I00
    Department: Química Analítica i Química Orgànica
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Publication Type: Journal Publications
    ISSN: 1040-0397
    Founding program 2: Programa Estatal De Generación De Conocimiento Y Fortalecimiento Científico y Tecnológico Del Sistema De I+D+i y del Programa Estatal De I+D+i Orientada los Retos de la Sociedad (Agencia Estatal de Investigación - Ministerio de Ciencia e Innovación).
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    e-ISSN: 1521-4109
    Thematic Areas: Saúde coletiva, Química, Psicología, Medicina ii, Medicina i, Materiais, Interdisciplinar, Geociências, Farmacia, Engenharias iii, Engenharias ii, Electrochemistry, Ciências biológicas ii, Ciências biológicas i, Ciências ambientais, Ciências agrárias i, Chemistry, analytical, Biotecnología, Biodiversidade, Astronomia / física, Analytical chemistry
    Acronym 2: SMARTCHEM
    Funding program action: Proyecto de I+D
    APA: Bouri, Mohamed; Zuaznabar-Gardona, Julio C; Novell, Marta; Blondeau, Pascal; Andrade, Francisco J (2021). Paper-based Potentiometric Biosensor for Monitoring Galactose in Whole Blood. Electroanalysis, 33(1), 81-89. DOI: 10.1002/elan.202060285
    Program founding action 2: Proyecto de I+D+i RTI Tipo B
    Article's DOI: 10.1002/elan.202060285
    Funding program: Programa Estatal de Investigación, Desarrollo e Innovación Orientada a los Retos de la Sociedad (Agencia Estatal de Investigación - Ministerio de Economía, Industria y Competitividad)
    Journal publication year: 2021
    Paper version: info:eu-repo/semantics/acceptedVersion
    Acronym: HOMESENS
    Author, as appears in the article.: Bouri, Mohamed; Zuaznabar-Gardona, Julio C; Novell, Marta; Blondeau, Pascal; Andrade, Francisco J
    Project code: CTQ2016-77128-R
    Author's mail: pascal.blondeau@urv.cat, franciscojavier.andrade@urv.cat

  • Keywords:

    Screen
    Potentiometry
    Paper-based platform
    Mno2
    Mixed potential
    Glucose
    Galactosemia
    Electrodes
    Diagnosis
    Cell
    Biosensor
    Analytical Chemistry
    Chemistry
    Analytical
    Electrochemistry
    Saúde coletiva
    Química
    Psicología
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Geociências
    Farmacia
    Engenharias iii
    Engenharias ii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Biotecnología
    Biodiversidade
    Astronomia / física

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