Author, as appears in the article.: Castro-Torres, Ruben Dario; Busquets, Oriol; Parcerisas, Antoni; Verdaguer, Ester; Olloquequi, Jordi; Etchetto, Miren; Beas-Zarate, Carlos; Folch, Jaume; Camins, Antoni; Auladell, Carme;
Department: Bioquímica i Biotecnologia
URV's Author/s: Folch Lopez, Jaume
Keywords: Wdr62 Synaptogenesis Synaptic function Signaling pathway Scg10 Scaffold proteins Phosphorylation Nmdar N-terminal kinase Migration Map1b Jnk1 Induced neurite outgrowth Distinct roles Dcx Axon elongation Asymmetric division Activation wdr62 scg10 nmdar migration map1b jnk1 dcx asymmetric division
Abstract: The c-Jun N-terminal Kinases (JNKs) are a group of regulatory elements responsible for the control of a wide array of functions within the cell. In the central nervous system (CNS), JNKs are involved in neuronal polarization, starting from the cell division of neural stem cells and ending with their final positioning when migrating and maturing. This review will focus mostly on isoform JNK1, the foremost contributor of total JNK activity in the CNS. Throughout the text, research from multiple groups will be summarized and discussed in order to describe the involvement of the JNKs in the different steps of neuronal polarization. The data presented support the idea that isoform JNK1 is highly relevant to the regulation of many of the processes that occur in neuronal development in the CNS.
Thematic Areas: Medicine (miscellaneous) Cell biology Biochemistry, genetics and molecular biology (miscellaneous) Biochemistry, genetics and molecular biology (all)
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 20734409
Author's mail: jaume.folch@urv.cat
Author identifier: 0000-0002-5051-8858
Record's date: 2023-04-15
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2073-4409/9/8/1897
Papper original source: Cells. 9 (8):
APA: Castro-Torres, Ruben Dario; Busquets, Oriol; Parcerisas, Antoni; Verdaguer, Ester; Olloquequi, Jordi; Etchetto, Miren; Beas-Zarate, Carlos; Folch, Jau (2020). Involvement of JNK1 in Neuronal Polarization During Brain Development. Cells, 9(8), -. DOI: 10.3390/cells9081897
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.3390/cells9081897
Entity: Universitat Rovira i Virgili
Journal publication year: 2020
Publication Type: Journal Publications
Repositori URV