Author, as appears in the article.: Cuesta M; Fuentes M; Rubio M; Bordiu E; Barabash A; Garcia de la Torre N; Rojo-Martinez G; Valdes S; Soriguer F; Vendrell JJ; Urrutia IM; Ortega E; Montanya E; Menendez E; Lago-Sampedro A; Gomis R; Goday A; Castell C; Badia-Guillen R; Girbés J; Gaztambide S; Franch-Nadal J; Delgado Álvarez E; Chaves FJ; Castano L; Calle-Pascual AL
Department: Medicina i Cirurgia
URV's Author/s: Vendrell Ortega, Juan José
Keywords: Waist circumference Time physical-activity Obesity Normal glucose regulation Metabolic syndrome Metaanalysis Mediterranean diet Lifestyle Life-style Exercise Epidemiology Cutoff points Association
Abstract: Introduction Metabolic syndrome (MetS) is an important predictor of cardiovascular mortality. Identification of occurrence and regression trends of MetS could permit elaboration of preventive strategies with new targets. The objective of this study was to analyze the occurrence and regression rates of MetS and its associated factors in the representative cohort of Spain of the di@bet.es study.
Research design and methods The di@bet.es study is a prospective cohort where 5072 people representative of the Spanish population over 18 years of age were randomly selected between 2009 and 2010. Follow-up was a median of 7.5 (IQR 7.2-7.9) years, with 2408 (47%) participating subjects. A total of 1881 (78%) subjects had all the pertinent data available and were included in this study.
Results Of the 1146 subjects without baseline criteria for MetS, 294 (25.7%) developed MetS during follow-up, while of the 735 patients with prior MetS, 148 (20.1%) presented regression. Adjusted MetS incidence per 1000 person-years was 38 (95% CI 32 to 44), while regression incidence was 36 (95% CI 31 to 41). Regression rate was independently higher than incidence rate in the following: women, subjects aged 18-45, university-degree holders, patients without central obesity, without hypertension, as well as those with body mass index of <25 kg/m(2). Lower progression and higher regression rates were observed with an adapted 14-point Mediterranean Diet adherence screener questionnaire score of >11 in both groups and with >500 and >2000 MET-min/week of physical activity, respectively.
Conclusions This study provides MetS incidence and regression rates, and identifies the target population for intervention strategies in Spain and possibly in other countries.
Thematic Areas: Medicina iii Interdisciplinar Engenharias iv Endocrinology, diabetes and metabolism Endocrinology & metabolism Ciências biológicas i Ciência da computação
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: juanjose.vendrell@urv.cat
Author identifier: 0000-0002-6994-6115
Record's date: 2023-02-19
Papper version: info:eu-repo/semantics/publishedVersion
Papper original source: Bmj Open Diabetes Research & Care. 8 (1):
APA: Cuesta M; Fuentes M; Rubio M; Bordiu E; Barabash A; Garcia de la Torre N; Rojo-Martinez G; Valdes S; Soriguer F; Vendrell JJ; Urrutia IM; Ortega E; Mo (2020). Incidence and regression of metabolic syndrome in a representative sample of the Spanish population: results of the cohort di@bet. Bmj Open Diabetes Research & Care, 8(1), -. DOI: 10.1136/bmjdrc-2020-001715
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Entity: Universitat Rovira i Virgili
Journal publication year: 2020
Publication Type: Journal Publications
Repositori URV