Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-9-335

Department: Bioquímica i Biotecnologia

URV's Author/s: Pallejà, Albert; D Harrington, Eoghan; Bork, Peer

Article's DOI: 10.1186/1471-2164-9-335

Abstract: Across the fully sequenced microbial genomes there are thousands of examples of overlapping genes. Many of these are only a few nucleotides long and are thought to function by permitting the coordinated regulation of gene expression. However, there should also be selective pressure against long overlaps, as the existence of overlapping reading frames increases the risk of deleterious mutations. Here we examine the longest overlaps and assess whether they are the product of special functional constraints or of erroneous annotation.

Journal publication year: 2008

licence for use: https://creativecommons.org/licenses/by/3.0/es/

Record's date: 2021-02-05

Journal volume: 9