Articles producció científica> Medicina i Cirurgia

Risk of atrial fibrillation, ischemic stroke and cognitive impairment: Study of a population cohort ≥65 years of age

  • Identification data

    Identifier: imarina:9138867
    Authors:
    Clua-Espuny JLMuria-Subirats EBallesta-Ors JLorman-Carbo BClua-Queralt JPalà ELechuga-Duran IGentille-Lorente DBustamante AMuñoz MÁMontaner J
    Abstract:
    © 2020 Clua-Espuny et al. Purpose: To evaluate a model for calculating the risk of AF and its relationship with the incidence of ischemic stroke and prevalence of cognitive decline. Materials and Methods: It was a multicenter, observational, retrospective, community-based study of a cohort of general population ≥6ct 35 years, between 01/01/2016 and 31/12/2018. Setting: Primary Care. Participants: 46,706 people ≥65 years with an active medical history in any of the primary care teams of the territory, information accessible through shared history and without previous known AF. Interventions: The model to stratify the risk of AF (PI) has been previously published and included the variables sex, age, mean heart rate, mean weight and CHA2DS2VASc score. Main measurements: For each risk group, the incidence density/1000 person/years of AF and stroke, number of cases required to detect a new AF, the prevalence of cognitive decline, Kendall correlation, and ROC curve were calculated. Results: The prognostic index was obtained in 37,731 cases (80.8%) from lowest (Q1) to highest risk (Q4). A total of 1244 new AFs and 234 stroke episodes were diagnosed. Q3-4 included 53.8% of all AF and 69.5% of strokes in men; 84.2% of all AF and 85.4% of strokes in women; and 77.4% of cases of cognitive impairment. There was a significant linear correlation between the risk-AF score and the Rankin score (p < 0.001), the Pfeiffer score (p < 0.001), but not NIHSS score (p 0.150). The overall NNS was 1/19. Conclusion: Risk stratification allows identifying high-risk individuals in whom to inter-vene on modifiable risk factors, prioritizing the diagnosis of AF and investigating cognitive status.
  • Others:

    Author, as appears in the article.: Clua-Espuny JL; Muria-Subirats E; Ballesta-Ors J; Lorman-Carbo B; Clua-Queralt J; Palà E; Lechuga-Duran I; Gentille-Lorente D; Bustamante A; Muñoz MÁ; Montaner J
    Department: Medicina i Cirurgia
    URV's Author/s: Ballesta Ors, Juan / Lorman Carbó, Blanca / Muria Subirats, Eulàlia
    Keywords: Vascular risk score Time factors Stroke Spain Silent stroke Sex factors Risk factors Risk assessment Retrospective studies Prognosis Prevention Prevalence Male Incidence Humans Female Cognitive dysfunction Cognitive decline Cognition Cerebrovascular disease Brain ischemia Atrial fibrillation Atrial arrhythmia Aged, 80 and over Aged survival silent stroke cognitive decline cerebrovascular disease atrial arrhythmia
    Abstract: © 2020 Clua-Espuny et al. Purpose: To evaluate a model for calculating the risk of AF and its relationship with the incidence of ischemic stroke and prevalence of cognitive decline. Materials and Methods: It was a multicenter, observational, retrospective, community-based study of a cohort of general population ≥6ct 35 years, between 01/01/2016 and 31/12/2018. Setting: Primary Care. Participants: 46,706 people ≥65 years with an active medical history in any of the primary care teams of the territory, information accessible through shared history and without previous known AF. Interventions: The model to stratify the risk of AF (PI) has been previously published and included the variables sex, age, mean heart rate, mean weight and CHA2DS2VASc score. Main measurements: For each risk group, the incidence density/1000 person/years of AF and stroke, number of cases required to detect a new AF, the prevalence of cognitive decline, Kendall correlation, and ROC curve were calculated. Results: The prognostic index was obtained in 37,731 cases (80.8%) from lowest (Q1) to highest risk (Q4). A total of 1244 new AFs and 234 stroke episodes were diagnosed. Q3-4 included 53.8% of all AF and 69.5% of strokes in men; 84.2% of all AF and 85.4% of strokes in women; and 77.4% of cases of cognitive impairment. There was a significant linear correlation between the risk-AF score and the Rankin score (p < 0.001), the Pfeiffer score (p < 0.001), but not NIHSS score (p 0.150). The overall NNS was 1/19. Conclusion: Risk stratification allows identifying high-risk individuals in whom to inter-vene on modifiable risk factors, prioritizing the diagnosis of AF and investigating cognitive status.
    Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Public health, environmental and occupational health Pharmacology (medical) Peripheral vascular disease Odontología Nutrição Medicine (miscellaneous) Medicina iii Medicina ii Medicina i Matemática / probabilidade e estatística Interdisciplinar Hematology Endocrinology, diabetes and metabolism Educação física Ciências biológicas ii Ciências ambientais Cardiology and cardiovascular medicine Biotecnología
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author identifier: 0000-0002-0971-0936
    Author's mail: blanca.lorman@estudiants.urv.cat
    Record's date: 2024-06-28
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.dovepress.com/risk-of-atrial-fibrillation-ischemic-stroke-and-cognitive-impairment-s-peer-reviewed-fulltext-article-VHRM
    Papper original source: Vascular Health And Risk Management. 16 445-454
    APA: Clua-Espuny JL; Muria-Subirats E; Ballesta-Ors J; Lorman-Carbo B; Clua-Queralt J; Palà E; Lechuga-Duran I; Gentille-Lorente D; Bustamante A; Muñoz MÁ; (2020). Risk of atrial fibrillation, ischemic stroke and cognitive impairment: Study of a population cohort ≥65 years of age. Vascular Health And Risk Management, 16(), 445-454. DOI: 10.2147/VHRM.S276477
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.2147/VHRM.S276477
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2020
    Publication Type: Journal Publications
  • Keywords:

    Cardiology and Cardiovascular Medicine,Endocrinology, Diabetes and Metabolism,Hematology,Medicine (Miscellaneous),Peripheral Vascular Disease,Pharmacology (Medical),Public Health, Environmental and Occupational Health
    Vascular risk score
    Time factors
    Stroke
    Spain
    Silent stroke
    Sex factors
    Risk factors
    Risk assessment
    Retrospective studies
    Prognosis
    Prevention
    Prevalence
    Male
    Incidence
    Humans
    Female
    Cognitive dysfunction
    Cognitive decline
    Cognition
    Cerebrovascular disease
    Brain ischemia
    Atrial fibrillation
    Atrial arrhythmia
    Aged, 80 and over
    Aged
    survival
    silent stroke
    cognitive decline
    cerebrovascular disease
    atrial arrhythmia
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Public health, environmental and occupational health
    Pharmacology (medical)
    Peripheral vascular disease
    Odontología
    Nutrição
    Medicine (miscellaneous)
    Medicina iii
    Medicina ii
    Medicina i
    Matemática / probabilidade e estatística
    Interdisciplinar
    Hematology
    Endocrinology, diabetes and metabolism
    Educação física
    Ciências biológicas ii
    Ciências ambientais
    Cardiology and cardiovascular medicine
    Biotecnología
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