Author, as appears in the article.: Moreno, G.; Carbonell, R.; Bodi, M.; Rodriguez, A.;
Department: Medicina i Cirurgia
URV's Author/s: Bodi Saera, Maria Amparo
Keywords: Thrombosis Society Sepsis Management Disseminated intravascular coagulation D-dimer Covid-19 Anticoagulation
Abstract: During the new pandemic caused by SARS-CoV-2, there is short knowledge regarding the management of different disease areas, such as coagulopathy and interpretation of D-dimer levels, its association with disseminated intravascular coagulation (DIC) and controversy about the benefit of anticoagulation. Thus, a systematic review has been performed to define the role of D-dimer in the disease, the prevalence of DIC and the usefulness of anticoagulant treatment in these patients. A literature search was performed to analyze the studies of COVID-19 patients. Four recommendations were drawn based on expert opinion and scientific knowledge, according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. The present review suggests the presence of higher levels of D-dimer in those with worse prognosis, there may be an overdiagnosis of DIC in the course of the disease and there is no evidence on the benefit of starting anticoagulant treatment based only on isolated laboratory data. (C) 2020 Elsevier Espana, S.L.U. y SEMICYUC. All rights reserved.
Thematic Areas: Medicina iii Medicina ii Medicina i General medicine Educação física Critical care medicine Critical care and intensive care medicine
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: mariaamparo.bodi@urv.cat mariaamparo.bodi@urv.cat
Author identifier: 0000-0001-7652-8379 0000-0001-7652-8379
Record's date: 2024-07-27
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://www.sciencedirect.com/science/article/abs/pii/S021056912030187X?via%3Dihub#!
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Medicina Intensiva. 45 (1): 42-55
APA: Moreno, G.; Carbonell, R.; Bodi, M.; Rodriguez, A.; (2021). Systematic review of the prognostic utility of D-dimer, disseminated intravascular coagulation, and anticoagulant therapy in COVID-19 critically ill patients. Medicina Intensiva, 45(1), 42-55. DOI: 10.1016/j.medin.2020.06.006
Article's DOI: 10.1016/j.medin.2020.06.006
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications
Repositori URV