Author, as appears in the article.: Caspersen IH; Iglesias Vazquez L; Abel MH; Brantsæter AL; Arija V; Erlund I; Meltzer HM
Department: Ciències Mèdiques Bàsiques
URV's Author/s: Arija Val, Maria Victoria / Iglesias Vazquez, Lucia
Keywords: Transferrin Pregnancy Keywords: Iron deficiency Interpregnancy interval Ferritin
Abstract: © The Authors 2021. Adequate iron supply in pregnancy is important for both the woman and the foetus, but iron status is often assessed late in first trimester, if assessed at all. Therefore, identification of factors associated with iron status is important to target vulnerable groups with increased risk of deficiency. Our objectives were to 1) describe iron status in mid-pregnancy and 2) identify sociodemographic and lifestyle predictors of pregnancy iron status. This cross-sectional study uses data from The Norwegian Mother, Father and Child Cohort Study (MoBa, collected 2002-2008) and The Medical Birth Registry of Norway. Iron status was measured as non-fasting plasma ferritin (P-Fe) and transferrin in gestational week 18 (n=2990), and by lowest reported haemoglobin (Hb) in gestational weeks 0-30 (n=39,322). We explored predictors of iron status with elastic net, linear and log-binomial regression models. Median P-Fe was 33 μg/L and 14 % had depleted iron stores (P-Fe <15 μg/L). P-Fe below 30 μg/L was associated with reduced Hb. We identified eleven predictors, with interpregnancy interval (IPI) and parity among the most important. Depleted iron stores was more common among women with IPI <6 months (56%) and 6-11 months (33%) than among those with IPI 24-59 months (19%) and among nulliparous women (5%). Positively associated factors with iron status included hormonal contraceptives, age, BMI, smoking, meat consumption, and multi-supplement use. Our results highlight the importance of ferritin measurements in women of childbearing age, especially among women not using hormonal contraceptives and women with previous and recent childbirths.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Nutrition and dietetics Nutrition & dietetics Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Matemática / probabilidade e estatística Interdisciplinar General medicine Farmacia Engenharias iv Engenharias ii Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Biotecnología Biodiversidade Administração pública e de empresas, ciências contábeis e turismo
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: lucia.iglesias@urv.cat victoria.arija@urv.cat
Author identifier: 0000-0001-7131-4144 0000-0002-1758-0975
Record's date: 2024-07-27
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/abs/iron-status-in-midpregnancy-and-associations-with-interpregnancy-interval-hormonal-contraceptives-dietary-factors-and-supplement-use/9D4081D89F8EF05794FEA8C3E30AA2AF
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: British Journal Of Nutrition. 126 (8): 1-11
APA: Caspersen IH; Iglesias Vazquez L; Abel MH; Brantsæter AL; Arija V; Erlund I; Meltzer HM (2021). Iron status in mid-pregnancy and associations with interpregnancy interval, hormonal contraceptives, dietary factors and supplement use. British Journal Of Nutrition, 126(8), 1-11. DOI: 10.1017/S0007114521000295
Article's DOI: 10.1017/S0007114521000295
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications