Articles producció científica> Ciències Mèdiques Bàsiques

Iron status in mid-pregnancy and associations with interpregnancy interval, hormonal contraceptives, dietary factors and supplement use

  • Identification data

    Identifier: imarina:9156122
    Authors:
    Caspersen IHIglesias Vazquez LAbel MHBrantsæter ALArija VErlund IMeltzer HM
    Abstract:
    © The Authors 2021. Adequate iron supply in pregnancy is important for both the woman and the foetus, but iron status is often assessed late in first trimester, if assessed at all. Therefore, identification of factors associated with iron status is important to target vulnerable groups with increased risk of deficiency. Our objectives were to 1) describe iron status in mid-pregnancy and 2) identify sociodemographic and lifestyle predictors of pregnancy iron status. This cross-sectional study uses data from The Norwegian Mother, Father and Child Cohort Study (MoBa, collected 2002-2008) and The Medical Birth Registry of Norway. Iron status was measured as non-fasting plasma ferritin (P-Fe) and transferrin in gestational week 18 (n=2990), and by lowest reported haemoglobin (Hb) in gestational weeks 0-30 (n=39,322). We explored predictors of iron status with elastic net, linear and log-binomial regression models. Median P-Fe was 33 μg/L and 14 % had depleted iron stores (P-Fe <15 μg/L). P-Fe below 30 μg/L was associated with reduced Hb. We identified eleven predictors, with interpregnancy interval (IPI) and parity among the most important. Depleted iron stores was more common among women with IPI <6 months (56%) and 6-11 months (33%) than among those with IPI 24-59 months (19%) and among nulliparous women (5%). Positively associated factors with iron status included hormonal contraceptives, age, BMI, smoking, meat consumption, and multi-supplement use. Our results highlight the importance of ferritin measurements in women of childbearing age, especially among women not using hormonal contraceptives and women with previous and recent childbirths.
  • Others:

    Author, as appears in the article.: Caspersen IH; Iglesias Vazquez L; Abel MH; Brantsæter AL; Arija V; Erlund I; Meltzer HM
    Department: Ciències Mèdiques Bàsiques
    URV's Author/s: Arija Val, Maria Victoria / Iglesias Vazquez, Lucia
    Keywords: Transferrin Pregnancy Keywords: Iron deficiency Interpregnancy interval Ferritin
    Abstract: © The Authors 2021. Adequate iron supply in pregnancy is important for both the woman and the foetus, but iron status is often assessed late in first trimester, if assessed at all. Therefore, identification of factors associated with iron status is important to target vulnerable groups with increased risk of deficiency. Our objectives were to 1) describe iron status in mid-pregnancy and 2) identify sociodemographic and lifestyle predictors of pregnancy iron status. This cross-sectional study uses data from The Norwegian Mother, Father and Child Cohort Study (MoBa, collected 2002-2008) and The Medical Birth Registry of Norway. Iron status was measured as non-fasting plasma ferritin (P-Fe) and transferrin in gestational week 18 (n=2990), and by lowest reported haemoglobin (Hb) in gestational weeks 0-30 (n=39,322). We explored predictors of iron status with elastic net, linear and log-binomial regression models. Median P-Fe was 33 μg/L and 14 % had depleted iron stores (P-Fe <15 μg/L). P-Fe below 30 μg/L was associated with reduced Hb. We identified eleven predictors, with interpregnancy interval (IPI) and parity among the most important. Depleted iron stores was more common among women with IPI <6 months (56%) and 6-11 months (33%) than among those with IPI 24-59 months (19%) and among nulliparous women (5%). Positively associated factors with iron status included hormonal contraceptives, age, BMI, smoking, meat consumption, and multi-supplement use. Our results highlight the importance of ferritin measurements in women of childbearing age, especially among women not using hormonal contraceptives and women with previous and recent childbirths.
    Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Nutrition and dietetics Nutrition & dietetics Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Matemática / probabilidade e estatística Interdisciplinar General medicine Farmacia Engenharias iv Engenharias ii Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Biotecnología Biodiversidade Administração pública e de empresas, ciências contábeis e turismo
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: lucia.iglesias@urv.cat victoria.arija@urv.cat
    Author identifier: 0000-0001-7131-4144 0000-0002-1758-0975
    Record's date: 2024-07-27
    Papper version: info:eu-repo/semantics/acceptedVersion
    Link to the original source: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/abs/iron-status-in-midpregnancy-and-associations-with-interpregnancy-interval-hormonal-contraceptives-dietary-factors-and-supplement-use/9D4081D89F8EF05794FEA8C3E30AA2AF
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: British Journal Of Nutrition. 126 (8): 1-11
    APA: Caspersen IH; Iglesias Vazquez L; Abel MH; Brantsæter AL; Arija V; Erlund I; Meltzer HM (2021). Iron status in mid-pregnancy and associations with interpregnancy interval, hormonal contraceptives, dietary factors and supplement use. British Journal Of Nutrition, 126(8), 1-11. DOI: 10.1017/S0007114521000295
    Article's DOI: 10.1017/S0007114521000295
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Medicine (Miscellaneous),Nutrition & Dietetics,Nutrition and Dietetics
    Transferrin
    Pregnancy
    Keywords:
    Iron deficiency
    Interpregnancy interval
    Ferritin
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Odontología
    Nutrition and dietetics
    Nutrition & dietetics
    Nutrição
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Matemática / probabilidade e estatística
    Interdisciplinar
    General medicine
    Farmacia
    Engenharias iv
    Engenharias ii
    Educação física
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Biotecnología
    Biodiversidade
    Administração pública e de empresas, ciências contábeis e turismo
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