Author, as appears in the article.: Ferre, Natalia; Luque, Veronica; Closa-Monasterolo, Ricardo; Zaragoza-Jordana, Marta; Gispert-Llaurado, Mariona; Grote, Veit; Koletzko, Berthold; Escribano, Joaquin;
Department: Medicina i Cirurgia
URV's Author/s: Closa Monasterolo, Ricardo / Escribano Subías, Joaquín / Ferre Pallas, Natalia / Gispert Llauradó, Mariona / Luque Moreno, Verònica / Zaragoza Jordana, Marta
Keywords: Weight gain Systematic review Risk factors Risk factor Review Randomized controlled trial Protein intake Preschool child Pediatric patient Pediatric obesity Overweight Obesity risk Obesity Metabolic programming Male Major clinical study Infant nutritional physiological phenomena Infant nutrition Infant Humans Human Female Fat mass Early protein intake Dietary proteins Controlled study Cohort analysis Clinical trials as topic Clinical trial (topic) Clinical outcome Childhood obesity Childhood Child, preschool Child nutritional physiological phenomena Child nutrition Child Cardiometabolic risk Body weight gain Body weight Body mass index Body mass Body fat Adverse event Administration and dosage Adiposity Adipose tissue
Abstract: There is accumulating evidence that early protein intake is related with weight gain in childhood. However, the evidence is mostly limited to the first year of life, whereas the high-weight-gain-velocity period extends up to about 2 years of age. We aimed to investigate whether protein intake during the second year of life is associated with higher weight gain and obesity risk later in childhood. We conducted a systematic review with searches in both PubMed(R)/MEDLINE(R) and the Cochrane Central Register of Controlled Trials. Ten studies that assessed a total of 46,170 children were identified. We found moderate-quality evidence of an association of protein intake during the second year of life with fat mass at 2 years and at 7 years. Effects on other outcomes such as body mass index (BMI), obesity risk, or adiposity rebound onset were inconclusive due to both heterogeneity and low evidence. We conclude that higher protein intakes during the second year of life are likely to increase fatness in childhood, but there is limited evidence regarding the association with other outcomes such as body mass index or change in adiposity rebound onset. Further well-designed and adequately powered clinical trials are needed since this issue has considerable public health relevance.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: mariona.gispert@urv.cat veronica.luque@urv.cat marta.zaragoza@urv.cat ricardo.closa@urv.cat natalia.ferre@urv.cat joaquin.escribano@urv.cat
Author identifier: 0000-0003-2615-8175 0000-0002-9963-4163 0000-0002-2838-1525 0000-0002-5041-459X
Record's date: 2024-07-27
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2072-6643/13/2/583
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Nutrients. 13 (2): 1-25
APA: Ferre, Natalia; Luque, Veronica; Closa-Monasterolo, Ricardo; Zaragoza-Jordana, Marta; Gispert-Llaurado, Mariona; Grote, Veit; Koletzko, Berthold; Escr (2021). Association of Protein Intake during the Second Year of Life with Weight Gain-Related Outcomes in Childhood: A Systematic Review. Nutrients, 13(2), 1-25. DOI: 10.3390/nu13020583
Article's DOI: 10.3390/nu13020583
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications
Repositori URV