Milk and Dairy Products Intake Is Related to Cognitive Impairment at Baseline in Predimed Plus Trial

Identifier:  imarina:9177884

Handle: https://hdl.handle.net/20.500.11797/imarina9177884

Authors:  Munoz-Garach, Araceli; Cornejo-Pareja, Isabel; Martinez-Gonzalez, Miguel angel; Bullo, Monica; Corella, Dolores; Castaner, Olga; Romaguera, Dora; Vioque, Jesus; Alonso-Gomez, Angel M; Warnberg, Julia; Martinez, J Alfredo; Serra-Majem, Luis; Estruch, Ramon; Bernal-Lopez, M Rosa; Lapetra, Jose; Pinto, Xavier; Tur, Josep A; Lopez-Miranda, Jose; Bueno-Cavanillas, Aurora; Delgado-Rodriguez, Miguel; Matia-Martin, Pilar; Daimiel, Lidia; Sanchez, Vicente Martin; Vidal, Josep; Prieto, Lucia; Ros, Emilio; Fernandez-Aranda, Fernando; Camacho-Barcia, Lucia; Ortega-Azorin, Carolina; Soria, Maria; Fiol, Miquel; Compan-Gabucio, Laura; Goicolea-Guemez, Leire; Perez-Lopez, Jessica; Goni, Nuria; Perez-Cabrera, Judith; Sacanella, E; Fernandez-Garcia, Jose Carlos; Miro-Moriano, Leticia; Gimenez-Gracia, M; Razquin, C; Paz-Graniel, Indira; Guillem, Patricia; Zomeno, Maria Dolors; Monino, Manuel; Oncina-Canovas, Alejandro; Salaverria-Lete, Itziar; Toledo, Estefania; Salas-Salvado, Jordi; Schroder, Helmut; Tinahones, Francisco J

Abstract:
Scope To examine the association between milk and dairy products intake and the prevalence of cognitive decline among Spanish individuals at high cardiovascular risk. Methods and results Cross-sectional analyses are performed on baseline data from 6744 adults (aged 55-75 years old). Intake of milk and dairy products is estimated using a food frequency questionnaire grouped into quartiles. The risk of developing cognitive impairment is based on the Mini-Mental State Examination (MMSE). A higher prevalence of cognitive decline was found in subjects who consumed more grams. Patients with worse MMSE score (10-24) consumed a mean of 395.14 +/- 12.21 g, while patients with better MMSE score (27-30) consumed a mean of 341.23 +/- 2.73 g (p < 0.05). Those subjects with the lower milk consumption (<220 g/day) had a higher MMSE score (28.35 +/- 0.045). Higher intake of fermented dairy products was observed in participants with a lower MMSE score (OR 1.340, p = 0.003). A positive correlation was found between the consumption of whole milk and the MMSE score (r = 0.066, p < 0.001). Conclusions These findings suggest that greater consumption of milk and dairy products could be associated with greater cognitive decline according to MMSE. Conversely, consumption of whole-fat milk could be linked with less cognitive impairment in the cross-sectional study.