Author, as appears in the article.: Kapruwan, Pankaj; Acosta, Laura K.; Ferre-Borrull, Josep; Marsal, Lluis F.;

Department: Enginyeria Electrònica, Elèctrica i Automàtica

URV's Author/s: Acosta Capilla, Laura Karen / Ferré Borrull, José / Marsal Garví, Luis Francisco

Keywords: Rhodamine 6g Polyelectrolytes Photonic crystals Optical monitoring Nanoporous anodic alumina

Abstract: In this work, a methodology that exploits the optical properties of the nanoporous anodic alumina gradient index filters (NAA-GIFs) has been developed and applied to evaluate in real time the release dynamics of a cargo molecule, acting as a model drug, filling the pores. NAA-GIFs with two photonic stopbands (PSBs) were prepared with one of its stop bands in the same absorption wavelength range of the cargo molecule, whereas the second stopband away from this absorption range. Numerical simulation and experiments confirm that the relative height of the high reflectance bands in the reflectance spectra of NAA-GIFs filled with the drug can be related to the relative amount of drug filling the pores. This property has been applied in a flow cell setup to measure in real-time the release dynamics of NAA-GIFs with the inner pore surface modified by layer-by-layer deposition of polyelectrolytes and loaded with the cargo molecule. The methodology developed in this work acts as a tool for the study of drug delivery from porous nanostructures.

Thematic Areas: Physics, applied Nanoscience & nanotechnology Materials science, multidisciplinary Materials science (miscellaneous) Materials science (all) General materials science General chemical engineering Engenharias ii Chemistry, multidisciplinary Chemical engineering (miscellaneous) Chemical engineering (all)

licence for use: https://creativecommons.org/licenses/by/3.0/es/

Author's mail: laurakaren.acosta@urv.cat lluis.marsal@urv.cat josep.ferre@urv.cat laurakaren.acosta@urv.cat

Author identifier: 0000-0002-5976-1408 0000-0002-5210-5133

Record's date: 2023-05-14

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://www.mdpi.com/2079-4991/11/3/730

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Nanomaterials. 11 (3): 1-16

APA: Kapruwan, Pankaj; Acosta, Laura K.; Ferre-Borrull, Josep; Marsal, Lluis F.; (2021). Optical Platform to Analyze a Model Drug-Loading and Releasing Profile Based on Nanoporous Anodic Alumina Gradient Index Filters. Nanomaterials, 11(3), 1-16. DOI: 10.3390/nano11030730

Article's DOI: 10.3390/nano11030730

Entity: Universitat Rovira i Virgili

Journal publication year: 2021

Publication Type: Journal Publications