Articles producció científica> Bioquímica i Biotecnologia

High Fruit and Vegetable Consumption and Moderate Fat Intake Are Associated with Higher Carotenoid Concentration in Human Plasma

  • Identification data

    Identifier: imarina:9187119
    Authors:
    Marhuenda-Munoz, MariaRinaldi de Alvarenga, Jose FernandoHernaez, AlvaroTresserra-Rimbau, AnnaMartinez-Gonzalez, Miguel AngelSalas-Salvado, JordiCorella, DoloresMalcampo, MireiaMartinez, Jose AlfredoAlonso-Gomez, Angel M.Warnberg, JuliaVioque, JesusRomaguera, DoraLopez-Miranda, JoseEstruch, RamonTinahones, Francisco J.Lapetra, JoseSerra-Majem, J. LluisBueno-Cavanillas, AuroraTur, Josep A.Sanchez, Vicente MartinPinto, XavierDelgado-Rodriguez, MiguelMatia-Martin, PilarVidal, JosepVazquez, ClotildeDaimiel, LidiaRos, EmilioSerra-Mir, MerceVazquez-Ruiz, ZenaidaNishi, Stephanie K.Sorli, Jose V.Zomeno, Maria DoloresZulet, Maria AngelesVaquero-Luna, JessicaCarabano-Moral, RosaNotario-Barandiaran, LeyreMorey, MargaGarcia-Rios, AntonioGomez-Perez, Ana M.Santos-Lozano, Jose ManuelBuil-Cosiales, PilarBasora, JosepPortoles, OlgaSchroder, HelmutAbete, ItziarSalaverria-Lete, ItziarToledo, EstefaniaBabio, NancyFito, MontseMartinez-Huelamo, MiriamLamuela-Raventos, Rosa M.
    Abstract:
    Carotenoids are pigments contained mainly in fruit and vegetables (F&V) that have beneficial effects on cardiometabolic health. Due to their lipophilic nature, co-ingestion of fat appears to increase their bioavailability via facilitating transfer to the aqueous micellar phase during digestion. However, the extent to which high fat intake may contribute to increased carotenoid plasma concentrations is still unclear. The objective was to examine the degree to which the consumption of different amounts of both carotenoid-rich foods and fats is associated with plasma carotenoid concentrations within a Mediterranean lifestyle context (subsample from the PREDIMED-Plus study baseline) where consumption of F&V and fat is high. The study population was categorized into four groups according to their self-reported consumption of F&V and fat. Carotenoids were extracted from plasma samples and analyzed by HPLC-UV-VIS-QqQ-MS/MS. Carotenoid systemic concentrations were greater in high consumers of F&V than in low consumers of these foods (+3.04 mu mol/L (95% CI: 0.90, 5.17), p-value = 0.005), but circulating concentrations seemed to decrease when total fat intake was very high (-2.69 mu mol/L (-5.54; 0.16), p-value = 0.064). High consumption of F&V is associated with greater systemic levels of total carotenoids, in particular when fat intake is low-to-moderate rather than very high.
  • Others:

    Author, as appears in the article.: Marhuenda-Munoz, Maria; Rinaldi de Alvarenga, Jose Fernando; Hernaez, Alvaro; Tresserra-Rimbau, Anna; Martinez-Gonzalez, Miguel Angel; Salas-Salvado, Jordi; Corella, Dolores; Malcampo, Mireia; Martinez, Jose Alfredo; Alonso-Gomez, Angel M.; Warnberg, Julia; Vioque, Jesus; Romaguera, Dora; Lopez-Miranda, Jose; Estruch, Ramon; Tinahones, Francisco J.; Lapetra, Jose; Serra-Majem, J. Lluis; Bueno-Cavanillas, Aurora; Tur, Josep A.; Sanchez, Vicente Martin; Pinto, Xavier; Delgado-Rodriguez, Miguel; Matia-Martin, Pilar; Vidal, Josep; Vazquez, Clotilde; Daimiel, Lidia; Ros, Emilio; Serra-Mir, Merce; Vazquez-Ruiz, Zenaida; Nishi, Stephanie K.; Sorli, Jose V.; Zomeno, Maria Dolores; Zulet, Maria Angeles; Vaquero-Luna, Jessica; Carabano-Moral, Rosa; Notario-Barandiaran, Leyre; Morey, Marga; Garcia-Rios, Antonio; Gomez-Perez, Ana M.; Santos-Lozano, Jose Manuel; Buil-Cosiales, Pilar; Basora, Josep; Portoles, Olga; Schroder, Helmut; Abete, Itziar; Salaverria-Lete, Itziar; Toledo, Estefania; Babio, Nancy; Fito, Montse; Martinez-Huelamo, Miriam; Lamuela-Raventos, Rosa M.;
    Department: Bioquímica i Biotecnologia
    URV's Author/s: Babio Sánchez, Nancy Elvira / Basora Gallisa, Josep / Nishi, Stephanie Kimiko / Salas Salvadó, Jorge
    Keywords: Predimed-plus study Plasma carotenoids Phytochemicals Mediterranean diet Matrix effect absorption Mass spectrometry Liquid chromatography Dietary fats Bioactive compounds
    Abstract: Carotenoids are pigments contained mainly in fruit and vegetables (F&V) that have beneficial effects on cardiometabolic health. Due to their lipophilic nature, co-ingestion of fat appears to increase their bioavailability via facilitating transfer to the aqueous micellar phase during digestion. However, the extent to which high fat intake may contribute to increased carotenoid plasma concentrations is still unclear. The objective was to examine the degree to which the consumption of different amounts of both carotenoid-rich foods and fats is associated with plasma carotenoid concentrations within a Mediterranean lifestyle context (subsample from the PREDIMED-Plus study baseline) where consumption of F&V and fat is high. The study population was categorized into four groups according to their self-reported consumption of F&V and fat. Carotenoids were extracted from plasma samples and analyzed by HPLC-UV-VIS-QqQ-MS/MS. Carotenoid systemic concentrations were greater in high consumers of F&V than in low consumers of these foods (+3.04 mu mol/L (95% CI: 0.90, 5.17), p-value = 0.005), but circulating concentrations seemed to decrease when total fat intake was very high (-2.69 mu mol/L (-5.54; 0.16), p-value = 0.064). High consumption of F&V is associated with greater systemic levels of total carotenoids, in particular when fat intake is low-to-moderate rather than very high.
    Thematic Areas: Química Physiology Molecular biology Medicina ii Medicina i Interdisciplinar Food science & technology Food science Farmacia Engenharias ii Clinical biochemistry Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, medicinal Cell biology Biotecnología Biodiversidade Biochemistry & molecular biology Biochemistry
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: stephanie.nishi@urv.cat josep.basora@urv.cat josep.basora@urv.cat jordi.salas@urv.cat nancy.babio@urv.cat
    Author identifier: 0000-0003-2700-7459 0000-0003-3527-5277
    Record's date: 2024-07-27
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.mdpi.com/2076-3921/10/3/473
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Antioxidants. 10 (3): 1-14
    APA: Marhuenda-Munoz, Maria; Rinaldi de Alvarenga, Jose Fernando; Hernaez, Alvaro; Tresserra-Rimbau, Anna; Martinez-Gonzalez, Miguel Angel; Salas-Salvado, (2021). High Fruit and Vegetable Consumption and Moderate Fat Intake Are Associated with Higher Carotenoid Concentration in Human Plasma. Antioxidants, 10(3), 1-14. DOI: 10.3390/antiox10030473
    Article's DOI: 10.3390/antiox10030473
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Biochemistry,Biochemistry & Molecular Biology,Cell Biology,Chemistry, Medicinal,Clinical Biochemistry,Food Science,Food Science & Technology,Molecular Biology,Physiology
    Predimed-plus study
    Plasma carotenoids
    Phytochemicals
    Mediterranean diet
    Matrix effect absorption
    Mass spectrometry
    Liquid chromatography
    Dietary fats
    Bioactive compounds
    Química
    Physiology
    Molecular biology
    Medicina ii
    Medicina i
    Interdisciplinar
    Food science & technology
    Food science
    Farmacia
    Engenharias ii
    Clinical biochemistry
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Chemistry, medicinal
    Cell biology
    Biotecnología
    Biodiversidade
    Biochemistry & molecular biology
    Biochemistry
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