Author, as appears in the article.: Díaz-López, A; Paz-Graniel, I; Ruiz, V; Toledo, E; Becerra-Tomás, N; Corella, D; Castañer, O; Martínez, JA; Alonso-Gómez, AM; Wärnberg, J; Vioque, J; Romaguera, D; López-Miranda, J; Estruch, R; Tinahones, FJ; Lapetra, J; Serra-Majem, L; Bueno-Cavanillas, A; Tur, JA; Sánchez, VM; Pintó, X; Delgado-Rodríguez, M; Matía-Martín, P; Vidal, J; Vázquez, C; Daimiel, L; Villa, TF; Ros, E; Eguaras, S; Babio, N; Sorlí, JV; Goday, A; Abete, I; Sierra, LT; Barón-López, FJ; Torres-Collado, L; Morey, M; Garcia-Rios, A; Casas, R; Bernal-López, MR; Santos-Lozano, JM; Navarro, A; Gonzalez, JI; Zomeño, MD; Zulet, MA; Luna, JV; Ramallal, R; Fitó, M; Salas-Salvadó, J
Department: Ciències Mèdiques Bàsiques Bioquímica i Biotecnologia
URV's Author/s: Babio Sánchez, Nancy Elvira / Becerra Tomás, Nerea / Díaz López, Andres / Paz Graniel, Indira del Socorro / Ruiz Garcia, Verónica / Salas Salvadó, Jorge
Keywords: Tea Spain Risk Questionnaire Pathophysiology Outcomes Middle aged Metabolic syndrome x Metabolic syndrome Male Kidney Hyperfiltration Humans Human Health Glomerulus filtration rate Glomerular-filtration-rate Glomerular filtration rate Female Drinking behavior Cohort studies Cohort analysis Coffee consumption Coffee Cardiovascular-diseases Caffeine Association Aged
Abstract: It remains unclear whether caffeinated beverages could have deleterious renal effects in elderly population with underlying comorbid conditions. We investigated the associations between coffee, tea, or caffeine intake and 1-year changes in glomerular filtration rate (eGFR) in a large Spanish cohort of overweight/obese elderly with metabolic syndrome (MetS). This prospective analysis includes 5851 overweight/obese adults (55-75 years) with MetS from the PREDIMED-Plus study. We assessed coffee, tea, and caffeine consumption from a validated food-frequency questionnaire and creatinine-based eGFR using the Chronic Kidney Disease Epidemiology Collaboration equation. Multivariate-adjusted regression models were applied to test associations between baseline coffee, tea, or caffeine intake and 1-year eGFR changes. Caffeinated coffee (> 2 cups/day) and tea (at least 1 cup/day) drinkers had 0.88 and 0.93 mL/min/1.73 m(2) greater eGFR decrease respectively, compared to those with less than 1 cup/day of coffee consumption or non-tea drinkers. Furthermore, caffeinated coffee consumption of > 2 cups/day was associated with 1.19-fold increased risk of rapid eGFR decline > 3 mL/min/1.73 m(2) (95% CI 1.01-1.41). Similarly, individuals in the highest (median, 51.2 mg/day) tertile of caffeine intake had a 0.87 mL/min/1.73 m(2) greater eGFR decrease. Decaffeinated coffee was not associated with eGFR changes. In conclusion, higher consumption of caffeinated coffee, tea, and caffeine was associated with a greater 1-year eGFR decline in overweight/obese adults with MetS.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Odontología Nutrição Multidisciplinary sciences Multidisciplinary Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Letras / linguística Interdisciplinar Geografía Geociências Farmacia Engenharias iv Engenharias iii Engenharias ii Enfermagem Educação física Educação Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Biotecnología Biodiversidade Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: veronica.ruiz@urv.cat indiradelsocorro.paz@urv.cat andres.diaz@urv.cat nerea.becerra@urv.cat veronica.ruiz@urv.cat indiradelsocorro.paz@urv.cat jordi.salas@urv.cat nancy.babio@urv.cat
Author identifier: 0000-0002-3204-6877 0000-0002-7500-5629 0000-0002-4429-6507 0000-0002-3204-6877 0000-0003-2700-7459 0000-0003-3527-5277
Record's date: 2024-07-27
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.nature.com/articles/s41598-021-88028-7
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Scientific Reports. 11 (1):
APA: Díaz-López, A; Paz-Graniel, I; Ruiz, V; Toledo, E; Becerra-Tomás, N; Corella, D; Castañer, O; Martínez, JA; Alonso-Gómez, AM; Wärnberg, J; Vioque, J; (2021). Consumption of caffeinated beverages and kidney function decline in an elderly Mediterranean population with metabolic syndrome. Scientific Reports, 11(1), -. DOI: 10.1038/s41598-021-88028-7
Article's DOI: 10.1038/s41598-021-88028-7
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications
Repositori URV