Author, as appears in the article.: Fontanals, N; Zohar, J; Borrull, F; Ronka, S; Marce, R M
Department: Química Analítica i Química Orgànica
URV's Author/s: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / Marcé Recasens, Rosa Maria
Keywords: Weak cation-exchange interactions Weak cation-exchange interaction Water sampling Water pollutants, chemical Water pollutant Water analysis Wastewater Waste-water Waste water Temperature measurement Synthesis Sorption Sorbents Sorbent Solid-phase extraction Solid-phase Solid phasis Solid phase extraction Sewage effluent Scanning electron microscopy Resins Residues Process optimization Procedures Positive ions Polymers Physical parameters Physical chemistry Phase separation Pharmaceuticals Pharmaceutical preparations Mesoporous sorbent Mass-spectrometry Mass spectrometry Maleic acids Maleic acid derivative Maleic acid Maleates Liquid chromatography Isolation and purification Extraction Exchange character Environmental water samples Environmental samples Environmental sample Effluents Drugs Drug products Drug Divinylbenzene Controlled study Chromatography, liquid Chromatography Chemistry Chemical interaction Chemical analysis Cation exchanges Basic drugs Article
Abstract: This study presents a novel mixed-mode weak cation-exchange (WCX) material. This material was prepared by means of the functionalization of a mesoporous divinylbenzene (DVB) resin with maleic acid (maleic acid-DVB), which yielded a high carboxylic moiety content resulting in WCX interactions as well as suitable specific surface area for reversed-phase interactions. After the optimization of the solid-phase extraction (SPE) protocol to enhance the selectivity of the sorbent, this material was evaluated as a novel WCX sorbent in the SPE of a group of drugs from environmental water samples. The method is based on SPE followed by liquid chromatography (LC) coupled to high resolution mass spectrometry (HRMS) with an Orbitrap analyzer, and was validated and applied for the determination of basic drugs in river, effluent and influent wastewater samples. Maleic acid-DVB sorbent yielded suitable recovery rates (57% to 89%) and an acceptable matrix effect ( < 32%) thanks to the effective washing step included when these environmental waters were loaded through the novel resin. The method was applied to different environmental water samples and some basic drugs were suitably quantified in these environmental samples.
(c) 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ )
Thematic Areas: Zootecnia / recursos pesqueiros Química Organic chemistry Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine Farmacia Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, analytical Biotecnología Biodiversidade Biochemistry Biochemical research methods Analytical chemistry
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: nuria.fontanals@urv.cat nuria.fontanals@urv.cat rosamaria.marce@urv.cat francesc.borrull@urv.cat
Author identifier: 0000-0002-7534-1964 0000-0002-7534-1964 0000-0002-5667-2899 0000-0003-2718-9336
Record's date: 2024-10-12
Journal volume: 1647
Papper version: info:eu-repo/semantics/publishedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Journal Of Chromatography a. 1647 (462165): 462165-
APA: Fontanals, N; Zohar, J; Borrull, F; Ronka, S; Marce, R M (2021). Development of a maleic acid-based material to selectively solid-phase extract basic compounds from environmental samples. Journal Of Chromatography a, 1647(462165), 462165-. DOI: 10.1016/j.chroma.2021.462165
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications
Repositori URV