Articles producció científica> Psicologia

Acute Psychological Adverse Reactions in First-Time Ritual Ayahuasca Users A Prospective Case Series

  • Identification data

    Identifier: imarina:9217202
    Authors:
    Gomez-Sousa, MariaJimenez-Garrido, Daniel FOna, Genisdos Santos, Rafael GuimaraesHallak, Jaime E CAlcazar-Corcoles, Miguel AngelBouso, Jose Carlos
    Abstract:
    Background In recent decades, ritualistic use of ayahuasca has spread throughout the world. Retrospective studies have suggested a good psychological safety profile, but prospective studies involving ceremony ayahuasca-naive participants are lacking. Methods We conducted the study using a subsample from a previous study, for which first-time ceremony ayahuasca participants were recruited. The subsample consisted of 7 subjects who experienced acute and challenging psychological reactions. The semistructured Mini-International Neuropsychiatric Interview and psychometric questionnaires were administered before participants attended the ayahuasca ceremony and at 1 and 6 months after exposure. Subjective experiences were also recorded. Results Seven subjects from a sample of 40 reported having experienced intense challenging psychological effects during the ayahuasca ceremony. Four of those 7 subjects met the diagnostic criteria for 1 or more psychiatric disorder before the ayahuasca ceremony. One month after the ceremony, 2 of those subjects no longer showed psychiatric symptoms, whereas the symptoms of the other 2 were reduced considerably. Those results persisted at the 6-month follow-up. Inappropriate setting/context (poor guiding skills and screening) contributed to some of the challenging reactions. Most of the participants (6 of 7) did not take ayahuasca again during the study period. Conclusions Based on the cases reported here, we suggest that although it is possible that participating in ayahuasca ceremonies may entail acute psychological negative reactions, those challenging experiences can also have positive long-term effects. Prospective research on the safety profile of ayahuasca and how it is affected by the context of different practices and safety strategies
  • Others:

    Author, as appears in the article.: Gomez-Sousa, Maria; Jimenez-Garrido, Daniel F; Ona, Genis; dos Santos, Rafael Guimaraes; Hallak, Jaime E C; Alcazar-Corcoles, Miguel Angel; Bouso, Jose Carlos
    Department: Psicologia
    URV's Author/s: Oña Esteve, Genís
    Keywords: Spanish version Safety Recurrent depression Psychedelic drugs Psilocybin Life Ayahuasca Adverse events
    Abstract: Background In recent decades, ritualistic use of ayahuasca has spread throughout the world. Retrospective studies have suggested a good psychological safety profile, but prospective studies involving ceremony ayahuasca-naive participants are lacking. Methods We conducted the study using a subsample from a previous study, for which first-time ceremony ayahuasca participants were recruited. The subsample consisted of 7 subjects who experienced acute and challenging psychological reactions. The semistructured Mini-International Neuropsychiatric Interview and psychometric questionnaires were administered before participants attended the ayahuasca ceremony and at 1 and 6 months after exposure. Subjective experiences were also recorded. Results Seven subjects from a sample of 40 reported having experienced intense challenging psychological effects during the ayahuasca ceremony. Four of those 7 subjects met the diagnostic criteria for 1 or more psychiatric disorder before the ayahuasca ceremony. One month after the ceremony, 2 of those subjects no longer showed psychiatric symptoms, whereas the symptoms of the other 2 were reduced considerably. Those results persisted at the 6-month follow-up. Inappropriate setting/context (poor guiding skills and screening) contributed to some of the challenging reactions. Most of the participants (6 of 7) did not take ayahuasca again during the study period. Conclusions Based on the cases reported here, we suggest that although it is possible that participating in ayahuasca ceremonies may entail acute psychological negative reactions, those challenging experiences can also have positive long-term effects. Prospective research on the safety profile of ayahuasca and how it is affected by the context of different practices and safety strategies is therefore necessary.
    Thematic Areas: Sociología Saúde coletiva Psychiatry and mental health Psychiatry Psicología Pharmacology (medical) Pharmacology & pharmacy Medicine (all) Medicina iii Medicina ii Medicina i Matemática / probabilidade e estatística Interdisciplinar General medicine Farmacia Clinical neurology Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Biotecnología
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: genis.ona@urv.cat genis.ona@urv.cat
    Record's date: 2024-07-27
    Papper version: info:eu-repo/semantics/acceptedVersion
    Link to the original source: https://journals.lww.com/psychopharmacology/abstract/2021/03000/acute_psychological_adverse_reactions_in.13.aspx
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Journal Of Clinical Psychopharmacology. 41 (2): 163-171
    APA: Gomez-Sousa, Maria; Jimenez-Garrido, Daniel F; Ona, Genis; dos Santos, Rafael Guimaraes; Hallak, Jaime E C; Alcazar-Corcoles, Miguel Angel; Bouso, Jos (2021). Acute Psychological Adverse Reactions in First-Time Ritual Ayahuasca Users A Prospective Case Series. Journal Of Clinical Psychopharmacology, 41(2), 163-171. DOI: 10.1097/JCP.0000000000001343
    Article's DOI: 10.1097/JCP.0000000000001343
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Clinical Neurology,Pharmacology & Pharmacy,Pharmacology (Medical),Psychiatry,Psychiatry and Mental Health
    Spanish version
    Safety
    Recurrent depression
    Psychedelic drugs
    Psilocybin
    Life
    Ayahuasca
    Adverse events
    Sociología
    Saúde coletiva
    Psychiatry and mental health
    Psychiatry
    Psicología
    Pharmacology (medical)
    Pharmacology & pharmacy
    Medicine (all)
    Medicina iii
    Medicina ii
    Medicina i
    Matemática / probabilidade e estatística
    Interdisciplinar
    General medicine
    Farmacia
    Clinical neurology
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Biotecnología
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