Articles producció científica> Medicina i Cirurgia

Gut microbiota profile and its association with clinical variables and dietary intake in overweight/obese and lean subjects: A cross-sectional study

  • Identification data

    Identifier: imarina:9218785
    Authors:
    Companys, JuditGosalbes, Maria JosePla-Paga, LauraCalderon-Perez, LorenaLlaurado, ElisabetPedret, AnnaValls, Rosa MariaJimenez-Hernandez, NuriaSandoval-Ramirez, Berner Andreedel Bas, Josep MariaCaimari, AntoniRubio, LauraSola, Rosa
    Abstract:
    We aimed to differentiate gut microbiota composition of overweight/obese and lean subjects and to determine its association with clinical variables and dietary intake. A cross-sectional study was performed with 96 overweight/obese subjects and 32 lean subjects. Anthropometric parameters were positively associated with Collinsella aerofaciens, Dorea formicigenerans and Dorea longicatena, which had higher abundance the overweight/obese subjects. Moreover, different genera of Lachnospiraceae were negatively associated with body fat, LDL and total cholesterol. Saturated fatty acids (SFAs) were negatively associated with the genus Intestinimonas, a biomarker of the overweight/obese group, whereas SFAs were positively associated with Roseburia, a biomarker for the lean group. In conclusion, Dorea formicigenerans, Dorea longicatena and Collinsella aerofaciens could be considered obesity biomarkers, Lachnospiraceae is associated with lipid cardiovascular risk factors. SFAs exhibited opposite association profiles with butyrate-producing bacteria depending on the BMI. Thus, the relationship between diet and microbiota opens new tools for the management of obesity.
  • Others:

    Author, as appears in the article.: Companys, Judit; Gosalbes, Maria Jose; Pla-Paga, Laura; Calderon-Perez, Lorena; Llaurado, Elisabet; Pedret, Anna; Valls, Rosa Maria; Jimenez-Hernandez, Nuria; Sandoval-Ramirez, Berner Andree; del Bas, Josep Maria; Caimari, Antoni; Rubio, Laura; Sola, Rosa
    Department: Medicina i Cirurgia
    URV's Author/s: Calderon Pérez, Lorena / Companys Alemany, Judit / Llauradó Ribé, Elisabet / Pedret Figuerola, Anna / PLA PAGA, LAURA / SANDOVAL RAMÍREZ, BERNER ANDRÉE / Solà Alberich, Rosa Maria / Valls Zamora, Rosa Maria
    Keywords: Thinness Saturated fatty acids Potassium Overweight Obesity Middle aged Male Humans Gut microbiota Gastrointestinal microbiome Female Feces Energy intake Eating Dietary intake Dietary fats Dietary carbohydrates Diet Cross-sectional studies Clostridiales Body mass index Bacteria Adult Actinobacteria weight saturated fatty acids population gut microbiota dietary intake alignment
    Abstract: We aimed to differentiate gut microbiota composition of overweight/obese and lean subjects and to determine its association with clinical variables and dietary intake. A cross-sectional study was performed with 96 overweight/obese subjects and 32 lean subjects. Anthropometric parameters were positively associated with Collinsella aerofaciens, Dorea formicigenerans and Dorea longicatena, which had higher abundance the overweight/obese subjects. Moreover, different genera of Lachnospiraceae were negatively associated with body fat, LDL and total cholesterol. Saturated fatty acids (SFAs) were negatively associated with the genus Intestinimonas, a biomarker of the overweight/obese group, whereas SFAs were positively associated with Roseburia, a biomarker for the lean group. In conclusion, Dorea formicigenerans, Dorea longicatena and Collinsella aerofaciens could be considered obesity biomarkers, Lachnospiraceae is associated with lipid cardiovascular risk factors. SFAs exhibited opposite association profiles with butyrate-producing bacteria depending on the BMI. Thus, the relationship between diet and microbiota opens new tools for the management of obesity.
    Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: judit.companys@urv.cat lorena.calderon@urv.cat anna.pedret@urv.cat elisabet.llaurado@urv.cat judit.companys@urv.cat judit.companys@urv.cat lorena.calderon@urv.cat rosamaria.valls@urv.cat rosa.sola@urv.cat
    Author identifier: 0000-0003-1485-0818 0000-0003-0766-0733 0000-0002-5327-932X 0000-0002-7439-9531 0000-0003-1485-0818 0000-0003-1485-0818 0000-0003-0766-0733 0000-0002-3351-0942 0000-0002-8359-235X
    Record's date: 2024-10-19
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.mdpi.com/2072-6643/13/6/2032
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Nutrients. 13 (6): 2032-
    APA: Companys, Judit; Gosalbes, Maria Jose; Pla-Paga, Laura; Calderon-Perez, Lorena; Llaurado, Elisabet; Pedret, Anna; Valls, Rosa Maria; Jimenez-Hernandez (2021). Gut microbiota profile and its association with clinical variables and dietary intake in overweight/obese and lean subjects: A cross-sectional study. Nutrients, 13(6), 2032-. DOI: 10.3390/nu13062032
    Article's DOI: 10.3390/nu13062032
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Food Science,Nutrition & Dietetics,Nutrition and Dietetics
    Thinness
    Saturated fatty acids
    Potassium
    Overweight
    Obesity
    Middle aged
    Male
    Humans
    Gut microbiota
    Gastrointestinal microbiome
    Female
    Feces
    Energy intake
    Eating
    Dietary intake
    Dietary fats
    Dietary carbohydrates
    Diet
    Cross-sectional studies
    Clostridiales
    Body mass index
    Bacteria
    Adult
    Actinobacteria
    weight
    saturated fatty acids
    population
    gut microbiota
    dietary intake
    alignment
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Psicología
    Planejamento urbano e regional / demografia
    Nutrition and dietetics
    Nutrition & dietetics
    Nutrição
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    Food science
    Farmacia
    Engenharias iv
    Engenharias ii
    Enfermagem
    Educação física
    Economia
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Biotecnología
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