Author, as appears in the article.: Companys J; Gosalbes MJ; Pla-Pagà L; Calderón-Pérez L; Llauradó E; Pedret A; Valls RM; Jiménez-Hernández N; Sandoval-Ramirez BA; Del Bas JM; Caimari A; Rubió L; Solà R
Department: Medicina i Cirurgia
URV's Author/s: Companys Alemany, Judit / Llauradó Ribé, Elisabet / Pedret Figuerola, Anna / PLA PAGA, LAURA / SANDOVAL RAMÍREZ, BERNER ANDRÉE / Solà Alberich, Rosa Maria / Valls Zamora, Rosa Maria
Keywords: Saturated fatty acids Obesity Gut microbiota Dietary intake weight saturated fatty acids population gut microbiota dietary intake alignment
Abstract: We aimed to differentiate gut microbiota composition of overweight/obese and lean subjects and to determine its association with clinical variables and dietary intake. A cross-sectional study was performed with 96 overweight/obese subjects and 32 lean subjects. Anthropometric parameters were positively associated with Collinsella aerofaciens, Dorea formicigenerans and Dorea longicatena, which had higher abundance the overweight/obese subjects. Moreover, different genera of Lachnospiraceae were negatively associated with body fat, LDL and total cholesterol. Saturated fatty acids (SFAs) were negatively associated with the genus Intestinimonas, a biomarker of the overweight/obese group, whereas SFAs were positively associated with Roseburia, a biomarker for the lean group. In conclusion, Dorea formicigenerans, Dorea longicatena and Collinsella aerofaciens could be considered obesity biomarkers, Lachnospiraceae is associated with lipid cardiovascular risk factors. SFAs exhibited opposite association profiles with butyrate-producing bacteria depending on the BMI. Thus, the relationship between diet and microbiota opens new tools for the management of obesity.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: judit.companys@urv.cat elisabet.llaurado@urv.cat anna.pedret@urv.cat rosa.sola@urv.cat rosamaria.valls@urv.cat judit.companys@urv.cat judit.companys@urv.cat
Author identifier: 0000-0003-1485-0818 0000-0002-7439-9531 0000-0002-5327-932X 0000-0002-8359-235X 0000-0002-3351-0942 0000-0003-1485-0818 0000-0003-1485-0818
Record's date: 2023-03-06
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2072-6643/13/6/2032
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Nutrients. 13 (6):
APA: Companys J; Gosalbes MJ; Pla-Pagà L; Calderón-Pérez L; Llauradó E; Pedret A; Valls RM; Jiménez-Hernández N; Sandoval-Ramirez BA; Del Bas JM; Caimari A (2021). Gut microbiota profile and its association with clinical variables and dietary intake in overweight/obese and lean subjects: A cross-sectional study. Nutrients, 13(6), -. DOI: 10.3390/nu13062032
Article's DOI: 10.3390/nu13062032
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications