Articles producció científica> Enginyeria Mecànica

From Supramolecular Hydrogels to Multifunctional Carriers for Biologically Active Substances

  • Identification data

    Identifier: imarina:9225167
    Authors:
    Skopinska-Wisniewska, JoannaDe la Flor, SilviaKozlowska, Justyna
    Abstract:
    Supramolecular hydrogels are 3D, elastic, water-swelled materials that are held together by reversible, non-covalent interactions, such as hydrogen bonds, hydrophobic, ionic, host-guest interactions, and metal-ligand coordination. These interactions determine the hydrogels' unique properties: mechanical strength; stretchability; injectability; ability to self-heal; shear-thinning; and sensitivity to stimuli, e.g., pH, temperature, the presence of ions, and other chemical substances. For this reason, supramolecular hydrogels have attracted considerable attention as carriers for active substance delivery systems. In this paper, we focused on the various types of non-covalent interactions. The hydrogen bonds, hydrophobic, ionic, coordination, and host-guest interactions between hydrogel components have been described. We also provided an overview of the recent studies on supramolecular hydrogel applications, such as cancer therapy, anti-inflammatory gels, antimicrobial activity, controlled gene drug delivery, and tissue engineering.
  • Others:

    Author, as appears in the article.: Skopinska-Wisniewska, Joanna; De la Flor, Silvia; Kozlowska, Justyna;
    Department: Enginyeria Mecànica
    URV's Author/s: De la Flor Lopez, Silvia
    Keywords: Tissue engineering Thermosensitive hydrogels Temperature System Supramolecular hydrogels Release Procedures Polymers Polymer Ph Non?covalent interactions Non-covalent interactions Ligands Ligand Ions Ion Injectable hydrogels Hydrophobic and hydrophilic interactions Hydrogen-ion concentration Hydrogels Hydrogel Gene-therapy Gene transfer techniques Gene transfer Drug-delivery Drug delivery systems Drug delivery system Drug delivery Doxorubicin Delayed-action preparations Delayed release formulation Cyclodextrin Controlled release Chitosan Chemistry Chemical phenomena Biomaterial Biocompatible materials Antineoplastic agents Antineoplastic agent Antiinflammatory agent Antiinfective agent Anti-inflammatory agents Anti-infective agents Acid
    Abstract: Supramolecular hydrogels are 3D, elastic, water-swelled materials that are held together by reversible, non-covalent interactions, such as hydrogen bonds, hydrophobic, ionic, host-guest interactions, and metal-ligand coordination. These interactions determine the hydrogels' unique properties: mechanical strength; stretchability; injectability; ability to self-heal; shear-thinning; and sensitivity to stimuli, e.g., pH, temperature, the presence of ions, and other chemical substances. For this reason, supramolecular hydrogels have attracted considerable attention as carriers for active substance delivery systems. In this paper, we focused on the various types of non-covalent interactions. The hydrogen bonds, hydrophobic, ionic, coordination, and host-guest interactions between hydrogel components have been described. We also provided an overview of the recent studies on supramolecular hydrogel applications, such as cancer therapy, anti-inflammatory gels, antimicrobial activity, controlled gene drug delivery, and tissue engineering.
    Thematic Areas: Zootecnia / recursos pesqueiros Spectroscopy Saúde coletiva Química Psicología Physical and theoretical chemistry Organic chemistry Odontología Nutrição Molecular biology Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Inorganic chemistry Geociências Farmacia Engenharias iv Engenharias ii Engenharias i Educação física Computer science applications Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Chemistry, multidisciplinary Catalysis Biotecnología Biodiversidade Biochemistry & molecular biology Astronomia / física
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: silvia.delaflor@urv.cat
    Author identifier: 0000-0002-6851-1371
    Record's date: 2024-07-27
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.mdpi.com/1422-0067/22/14/7402
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: International Journal Of Molecular Sciences. 22 (14):
    APA: Skopinska-Wisniewska, Joanna; De la Flor, Silvia; Kozlowska, Justyna; (2021). From Supramolecular Hydrogels to Multifunctional Carriers for Biologically Active Substances. International Journal Of Molecular Sciences, 22(14), -. DOI: 10.3390/ijms22147402
    Article's DOI: 10.3390/ijms22147402
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Biochemistry & Molecular Biology,Catalysis,Chemistry, Multidisciplinary,Computer Science Applications,Inorganic Chemistry,Medicine (Miscellaneous),Molecular Biology,Organic Chemistry,Physical and Theoretical Chemistry,Spectroscopy
    Tissue engineering
    Thermosensitive hydrogels
    Temperature
    System
    Supramolecular hydrogels
    Release
    Procedures
    Polymers
    Polymer
    Ph
    Non?covalent interactions
    Non-covalent interactions
    Ligands
    Ligand
    Ions
    Ion
    Injectable hydrogels
    Hydrophobic and hydrophilic interactions
    Hydrogen-ion concentration
    Hydrogels
    Hydrogel
    Gene-therapy
    Gene transfer techniques
    Gene transfer
    Drug-delivery
    Drug delivery systems
    Drug delivery system
    Drug delivery
    Doxorubicin
    Delayed-action preparations
    Delayed release formulation
    Cyclodextrin
    Controlled release
    Chitosan
    Chemistry
    Chemical phenomena
    Biomaterial
    Biocompatible materials
    Antineoplastic agents
    Antineoplastic agent
    Antiinflammatory agent
    Antiinfective agent
    Anti-inflammatory agents
    Anti-infective agents
    Acid
    Zootecnia / recursos pesqueiros
    Spectroscopy
    Saúde coletiva
    Química
    Psicología
    Physical and theoretical chemistry
    Organic chemistry
    Odontología
    Nutrição
    Molecular biology
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Inorganic chemistry
    Geociências
    Farmacia
    Engenharias iv
    Engenharias ii
    Engenharias i
    Educação física
    Computer science applications
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Ciência da computação
    Chemistry, multidisciplinary
    Catalysis
    Biotecnología
    Biodiversidade
    Biochemistry & molecular biology
    Astronomia / física
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