Author, as appears in the article.: Skopinska-Wisniewska, Joanna; De la Flor, Silvia; Kozlowska, Justyna;
Department: Enginyeria Mecànica
URV's Author/s: De la Flor Lopez, Silvia
Keywords: Tissue engineering Thermosensitive hydrogels Temperature System Supramolecular hydrogels Release Procedures Polymers Polymer Ph Non?covalent interactions Non-covalent interactions Ligands Ligand Ions Ion Injectable hydrogels Hydrophobic and hydrophilic interactions Hydrogen-ion concentration Hydrogels Hydrogel Gene-therapy Gene transfer techniques Gene transfer Drug-delivery Drug delivery systems Drug delivery system Drug delivery Doxorubicin Delayed-action preparations Delayed release formulation Cyclodextrin Controlled release Chitosan Chemistry Chemical phenomena Biomaterial Biocompatible materials Antineoplastic agents Antineoplastic agent Antiinflammatory agent Antiinfective agent Anti-inflammatory agents Anti-infective agents Acid
Abstract: Supramolecular hydrogels are 3D, elastic, water-swelled materials that are held together by reversible, non-covalent interactions, such as hydrogen bonds, hydrophobic, ionic, host-guest interactions, and metal-ligand coordination. These interactions determine the hydrogels' unique properties: mechanical strength; stretchability; injectability; ability to self-heal; shear-thinning; and sensitivity to stimuli, e.g., pH, temperature, the presence of ions, and other chemical substances. For this reason, supramolecular hydrogels have attracted considerable attention as carriers for active substance delivery systems. In this paper, we focused on the various types of non-covalent interactions. The hydrogen bonds, hydrophobic, ionic, coordination, and host-guest interactions between hydrogel components have been described. We also provided an overview of the recent studies on supramolecular hydrogel applications, such as cancer therapy, anti-inflammatory gels, antimicrobial activity, controlled gene drug delivery, and tissue engineering.
Thematic Areas: Zootecnia / recursos pesqueiros Spectroscopy Saúde coletiva Química Psicología Physical and theoretical chemistry Organic chemistry Odontología Nutrição Molecular biology Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Inorganic chemistry Geociências Farmacia Engenharias iv Engenharias ii Engenharias i Educação física Computer science applications Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Chemistry, multidisciplinary Catalysis Biotecnología Biodiversidade Biochemistry & molecular biology Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: silvia.delaflor@urv.cat
Author identifier: 0000-0002-6851-1371
Record's date: 2024-07-27
Papper version: info:eu-repo/semantics/publishedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: International Journal Of Molecular Sciences. 22 (14):
APA: Skopinska-Wisniewska, Joanna; De la Flor, Silvia; Kozlowska, Justyna; (2021). From Supramolecular Hydrogels to Multifunctional Carriers for Biologically Active Substances. International Journal Of Molecular Sciences, 22(14), -. DOI: 10.3390/ijms22147402
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications
Repositori URV