Articles producció científica> Bioquímica i Biotecnologia

Effect of low glycaemic index or load dietary patterns on glycaemic control and cardiometabolic risk factors in diabetes: systematic review and meta-analysis of randomised controlled trials

  • Identification data

    Identifier: imarina:9226186
    Authors:
    Chiavaroli, LauraLee, DanielleAhmed, AmnaCheung, AnnetteKhan, Tauseef A.Mejia, Sonia BlancoMirrahimi, ArashJenkins, David J. A.Livesey, GeoffreyWolever, Thomas M. S.Rahelic, DarioKahleova, HanaSalas-Salvado, JordiKendall, Cyril W. C.Sievenpiper, John L.
    Abstract:
    OBJECTIVE To inform the update of the European Association for the Study of Diabetes clinical practice guidelines for nutrition therapy. DESIGN Systematic review and meta-analysis of randomised controlled trials. DATA SOURCES Medline, Embase, and the Cochrane Library searched up to 13 May 2021. ELIGIBILITY CRITERIA FOR SELECTING STUDIES Randomised controlled trials of three or more weeks investigating the effect of diets with low glycaemic index (GI)/glycaemic load (GL) in diabetes. OUTCOME AND MEASURES The primary outcome was glycated haemoglobin (HbA1c). Secondary outcomes included other markers of glycaemic control (fasting glucose, fasting insulin); blood lipids (low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), non-HDL-C, apo B, triglycerides); adiposity (body weight, BMI, waist circumference), blood pressure (systolic blood pressure (SBP) and diastolic blood pressure (DBP)), and inflammation (C reactive protein (CRP)). DATA EXTRACTION AND SYNTHESIS Two independent reviewers extracted data and assessed risk of bias. Data were pooled by random effects models. GRADE (grading of recommendations assessment, development, and evaluation) was used to assess the certainty of evidence. RESULTS 29 trial comparisons were identified in 1617 participants with type 1 and 2 diabetes who were predominantly middle aged, overweight, or obese with moderately controlled type 2 diabetes treated by hyperglycaemia drugs or insulin. Low GI/GL dietary patterns reduced HbA1c in comparison with higher GI/GL control diets (mean difference & minus;0.31% (95% confidence interval & minus;0.42 to & minus;0.19%), P < 0.001; substantial heterogeneity, I2=75%, P < 0.001). Reductions occurred also in fasting glucose, LDL-C, non-HDL-C, apo B, triglycerides, bod
  • Others:

    Author, as appears in the article.: Chiavaroli, Laura; Lee, Danielle; Ahmed, Amna; Cheung, Annette; Khan, Tauseef A.; Mejia, Sonia Blanco; Mirrahimi, Arash; Jenkins, David J. A.; Livesey, Geoffrey; Wolever, Thomas M. S.; Rahelic, Dario; Kahleova, Hana; Salas-Salvado, Jordi; Kendall, Cyril W. C.; Sievenpiper, John L.;
    Department: Bioquímica i Biotecnologia
    URV's Author/s: Salas Salvadó, Jorge
    Keywords: Waist circumference Type-2 Triacylglycerol blood level Triacylglycerol Treatment response Treatment outcome Systolic blood pressure Systematic review Risk algorithm Review Randomized controlled trial (topic) Publication bias Practice guideline Patient identification Outcome assessment Obesity Nutrition therapy Non insulin dependent diabetes mellitus Mexican-style diet Metabolic control Meta analysis Low density lipoprotein cholesterol level Low density lipoprotein cholesterol Lipid profile Insulin dependent diabetes mellitus Insulin Inflammation Improves dietary Impaired glucose-tolerance Humans Human High density lipoprotein cholesterol level High density lipoprotein cholesterol Hemoglobin a1c Grade approach Glycemic load Glycemic index Glycemic control Glucose blood level Glucose Fasting Dietary pattern Diet, diabetic Diet therapy Diastolic blood pressure Diabetic diet Diabetes mellitus, type 2 Diabetes mellitus, type 1 Diabetes mellitus Coronary-heart-disease Clinical practice Cardiovascular-disease Cardiometabolic risk factors Cardiometabolic risk factor C reactive protein Body weight Body mass Apolipoprotein b type-2 publication bias nutrition therapy mexican-style diet metabolic control lipid profile improves dietary impaired glucose-tolerance cardiovascular-disease
    Abstract: OBJECTIVE To inform the update of the European Association for the Study of Diabetes clinical practice guidelines for nutrition therapy. DESIGN Systematic review and meta-analysis of randomised controlled trials. DATA SOURCES Medline, Embase, and the Cochrane Library searched up to 13 May 2021. ELIGIBILITY CRITERIA FOR SELECTING STUDIES Randomised controlled trials of three or more weeks investigating the effect of diets with low glycaemic index (GI)/glycaemic load (GL) in diabetes. OUTCOME AND MEASURES The primary outcome was glycated haemoglobin (HbA1c). Secondary outcomes included other markers of glycaemic control (fasting glucose, fasting insulin); blood lipids (low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), non-HDL-C, apo B, triglycerides); adiposity (body weight, BMI, waist circumference), blood pressure (systolic blood pressure (SBP) and diastolic blood pressure (DBP)), and inflammation (C reactive protein (CRP)). DATA EXTRACTION AND SYNTHESIS Two independent reviewers extracted data and assessed risk of bias. Data were pooled by random effects models. GRADE (grading of recommendations assessment, development, and evaluation) was used to assess the certainty of evidence. RESULTS 29 trial comparisons were identified in 1617 participants with type 1 and 2 diabetes who were predominantly middle aged, overweight, or obese with moderately controlled type 2 diabetes treated by hyperglycaemia drugs or insulin. Low GI/GL dietary patterns reduced HbA1c in comparison with higher GI/GL control diets (mean difference & minus;0.31% (95% confidence interval & minus;0.42 to & minus;0.19%), P < 0.001; substantial heterogeneity, I2=75%, P < 0.001). Reductions occurred also in fasting glucose, LDL-C, non-HDL-C, apo B, triglycerides, body weight, BMI, and CRP (P < 0.05), but not blood insulin, HDL-C, waist circumference, or blood pressure. A positive dose response gradient was seen for the difference in GL and HbA1c and for absolute dietary GI and SBP (P < 0.05). The certainty of evidence was high for the reduction in HbA1cand moderate for most secondary outcomes, with downgrades due mainly to imprecision. CONCLUSIONS This synthesis suggests that low GI/GL dietary patterns result in small important improvements in established targets of glycaemic control, blood lipids, adiposity, and inflammation beyond concurrent treatment with hyperglycaemia drugs or insulin, predominantly in adults with moderately controlled type 1 and type 2 diabetes. The available evidence provides a good indication of the likely benefit in this population. STUDY REGISTRATION ClinicalTrials.gov NCT04045938.<comment>Superscript/Subscript Available</comment
    Thematic Areas: Saúde coletiva Odontología Medicine, general & internal Medicina iii Medicina ii Medicina i Interdisciplinar Educação física Ciências biológicas i Biotecnología
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: jordi.salas@urv.cat
    Author identifier: 0000-0003-2700-7459
    Record's date: 2024-09-07
    Journal volume: 374
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.bmj.com/content/374/bmj.n1651
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Bmj-British Medical Journal. 374
    APA: Chiavaroli, Laura; Lee, Danielle; Ahmed, Amna; Cheung, Annette; Khan, Tauseef A.; Mejia, Sonia Blanco; Mirrahimi, Arash; Jenkins, David J. A.; Livesey (2021). Effect of low glycaemic index or load dietary patterns on glycaemic control and cardiometabolic risk factors in diabetes: systematic review and meta-analysis of randomised controlled trials. Bmj-British Medical Journal, 374(), -. DOI: 10.1136/bmj.n1651
    Article's DOI: 10.1136/bmj.n1651
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Medicine, General & Internal
    Waist circumference
    Type-2
    Triacylglycerol blood level
    Triacylglycerol
    Treatment response
    Treatment outcome
    Systolic blood pressure
    Systematic review
    Risk algorithm
    Review
    Randomized controlled trial (topic)
    Publication bias
    Practice guideline
    Patient identification
    Outcome assessment
    Obesity
    Nutrition therapy
    Non insulin dependent diabetes mellitus
    Mexican-style diet
    Metabolic control
    Meta analysis
    Low density lipoprotein cholesterol level
    Low density lipoprotein cholesterol
    Lipid profile
    Insulin dependent diabetes mellitus
    Insulin
    Inflammation
    Improves dietary
    Impaired glucose-tolerance
    Humans
    Human
    High density lipoprotein cholesterol level
    High density lipoprotein cholesterol
    Hemoglobin a1c
    Grade approach
    Glycemic load
    Glycemic index
    Glycemic control
    Glucose blood level
    Glucose
    Fasting
    Dietary pattern
    Diet, diabetic
    Diet therapy
    Diastolic blood pressure
    Diabetic diet
    Diabetes mellitus, type 2
    Diabetes mellitus, type 1
    Diabetes mellitus
    Coronary-heart-disease
    Clinical practice
    Cardiovascular-disease
    Cardiometabolic risk factors
    Cardiometabolic risk factor
    C reactive protein
    Body weight
    Body mass
    Apolipoprotein b
    type-2
    publication bias
    nutrition therapy
    mexican-style diet
    metabolic control
    lipid profile
    improves dietary
    impaired glucose-tolerance
    cardiovascular-disease
    Saúde coletiva
    Odontología
    Medicine, general & internal
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    Educação física
    Ciências biológicas i
    Biotecnología
  • Documents:

  • Cerca a google

    Search to google scholar