Author, as appears in the article.: Margalef, Jessica; Biosca, Maria; de la Cruz Sanchez, Pol; Faiges, Jorge; Pamies, Oscar; Dieguez, Montserrat;
Department: Química Física i Inorgànica
URV's Author/s: Biosca Brull, Maria / De La Cruz Sánchez Badia, Pol / Diéguez Fernández, Montserrat / Faiges Marcos, Jorge / Margalef Pallarès, Jèssica / Pamies Ollé, Oscar
Keywords: Transition-metal-complexes Selective 1,1-binaphthyl synthesis Phosphorus-containing oxazoline Phosphite-oxazoline ligands P-s ligands P-o ligands P-n ligands Minimally functionalized olefins Ligand design Enantioselective total-synthesis Diastereoselective mannich reaction Atropisomeric phosphinamine ligand Asymmetric catalysis Alpha,beta-unsaturated carboxylic-acids Allylic substitution-reactions
Abstract: The success of phosphine-oxazoline ligands (PHOX) inspired the progress in P-oxazoline ligand families by modifying either the ligand backbone, the electronic and/or steric properties of the phosphine group or by exchanging the phosphine to a phosphinite or a phosphite group. In this respect, the structures of chiral P-oxazoline ligands have become more diverse and new families of very efficient ligands have emerged, which have improved catalytic performance in some asymmetric transformations, with an increased versatility, both in the range of reactions and in the range of substrates/reagents. In addition, most of ligands are synthesized from easily accessible chiral amino alcohols, maintaining the short and efficient synthetic route developed for PHOX ligands. New ligands have been developed by replacing the oxazoline functionality with several other N-donor groups, e.g. imidazole, thiazole, oxazole, pyridine, etc., and O- and S-groups. This review offers a critical overview of the utility of these most successful bidentate heterodonor P-N, P-O and P-S ligand families applied in metal-mediated processes. We illustrate how, through proper ligand design, these heterodonor bidentate ligand families can be an excellent source of ligands, with superior catalytic performance in many asymmetric reactions than the best C-2-symmetric N,N and P,P-ligands reported so far. (C) 2021 The Authors. Published by Elsevier B.V.
Thematic Areas: Química Physical and theoretical chemistry Medicina ii Materials chemistry Materiais Interdisciplinar Inorganic chemistry General chemistry Farmacia Engenharias iv Ciências biológicas ii Chemistry, inorganic & nuclear Chemistry (miscellaneous) Chemistry (all) Biotecnología Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: maria.biosca@urv.cat pol.delacruzsanchez@estudiants.urv.cat pol.delacruzsanchez@estudiants.urv.cat jorge.faiges@urv.cat oscar.pamies@urv.cat montserrat.dieguez@urv.cat
Author identifier: 0000-0002-9116-6318 0000-0002-2352-8508 0000-0002-8450-0656
Record's date: 2024-07-27
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.sciencedirect.com/science/article/pii/S0010854521003945
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Coordination Chemistry Reviews. 446
APA: Margalef, Jessica; Biosca, Maria; de la Cruz Sanchez, Pol; Faiges, Jorge; Pamies, Oscar; Dieguez, Montserrat; (2021). Evolution in heterodonor P-N, P-S and P-O chiral ligands for preparing efficient catalysts for asymmetric catalysis. From design to applications. Coordination Chemistry Reviews, 446(), -. DOI: 10.1016/j.ccr.2021.214120
Article's DOI: 10.1016/j.ccr.2021.214120
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications
Repositori URV