Author, as appears in the article.: Perez-Latorre, Leire; Berenguer, Juan; Mican, Rafael; Montero, Marta; Cifuentes, Carmen; Puig, Teresa; Sanz, Jose; Ferrero, Oscar L.; de la Fuente, Belen; Rodriguez, Carmen; Reus, Sergio; Hernandez-Quero, Jose; Gaspar, Gabriel; Perez-Martinez, Laura; Garcia, Coral; Force, Luis; Veloso, Sergio; De Miguel, Marta; Jarrin, Inmaculada; Gonzalez-Garcia, Juan;Gesida Study Grp

Department: Medicina i Cirurgia

URV's Author/s: PERAIRE FORNER, JOSÉ JOAQUIN

Keywords: Prevalence Mortality Impact Immunodeficiency Hepatitis-b Hcv Clearance B-virus coinfection Antiretroviral therapy

Abstract: Background: Recent and reliable estimates on the prevalence of coinfection with human immunodeficiency virus (HIV) and hepatitis B virus (HBV) in Europe are lacking. Aim: Leveraged on a study designed to assess HIV/HCV coinfection prevalence, we assessed the prevalence of HIV/HBV coinfection in Spain in 2018 and compared the results with five similar studies performed since 2002. Methods: This cross-sectional prevalence study was carried out in 43 centres, and patients were selected using simple random sampling. The reference population comprised 40,322 patients and the sample size were 1,690 patients. Results: The prevalence of HIV/HBV coinfection in Spain at the end of 2018 was 3.2%. The prevalence in 2002, 2009, 2015, 2016 and 2017 was 4.9%, 3.4%, 3%, 3.9% and 3%, respectively. Among the HIV/HBV-coinfected patients identified in 2018, 16.7% had cirrhosis according to transient elastography and 26.3% tested positive for antibodies against hepatitis D virus. All HIV/HBVcoinfected patients were receiving drugs with activity against HBV, and 97% of those tested for HBV DNA had an HBV DNA load < 80 IU/mL. Conclusions: The prevalence of HIV/HBV coinfection in Spain remained stable at around 3% for a decade. Our data could facilitate the design of national programmes to control HBV infection and help identify areas of patient management that need improvement.

Thematic Areas: Virology Saúde coletiva Public health, environmental and occupational health Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Infectious diseases General medicine Farmacia Epidemiology Ciências biológicas iii Ciências agrárias i Biotecnología

licence for use: https://creativecommons.org/licenses/by/3.0/es/

Author's mail: joaquim.peraire@urv.cat

Author identifier: 0000-0001-7808-5479

Record's date: 2021-10-10

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2021.26.25.2000236

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Eurosurveillance. 26 (25):

APA: Perez-Latorre, Leire; Berenguer, Juan; Mican, Rafael; Montero, Marta; Cifuentes, Carmen; Puig, Teresa; Sanz, Jose; Ferrero, Oscar L.; de la Fuente, Be (2021). HIV/HBV coinfection: temporal trends and patient characteristics, Spain, 2002 to 2018. Eurosurveillance, 26(25), -. DOI: 10.2807/1560-7917.ES.2021.26.25.2000236

Article's DOI: 10.2807/1560-7917.ES.2021.26.25.2000236

Entity: Universitat Rovira i Virgili

Journal publication year: 2021

Publication Type: Journal Publications