Articles producció científica> Medicina i Cirurgia

HIV/HBV coinfection: temporal trends and patient characteristics, Spain, 2002 to 2018

  • Identification data

    Identifier: imarina:9226940
    Authors:
    Perez-Latorre, LeireBerenguer, JuanMican, RafaelMontero, MartaCifuentes, CarmenPuig, TeresaSanz, JoseFerrero, Oscar L.de la Fuente, BelenRodriguez, CarmenReus, SergioHernandez-Quero, JoseGaspar, GabrielPerez-Martinez, LauraGarcia, CoralForce, LuisVeloso, SergioDe Miguel, MartaJarrin, InmaculadaGonzalez-Garcia, JuanGesida Study Grp
    Abstract:
    Background: Recent and reliable estimates on the prevalence of coinfection with human immunodeficiency virus (HIV) and hepatitis B virus (HBV) in Europe are lacking. Aim: Leveraged on a study designed to assess HIV/HCV coinfection prevalence, we assessed the prevalence of HIV/HBV coinfection in Spain in 2018 and compared the results with five similar studies performed since 2002. Methods: This cross-sectional prevalence study was carried out in 43 centres, and patients were selected using simple random sampling. The reference population comprised 40,322 patients and the sample size were 1,690 patients. Results: The prevalence of HIV/HBV coinfection in Spain at the end of 2018 was 3.2%. The prevalence in 2002, 2009, 2015, 2016 and 2017 was 4.9%, 3.4%, 3%, 3.9% and 3%, respectively. Among the HIV/HBV-coinfected patients identified in 2018, 16.7% had cirrhosis according to transient elastography and 26.3% tested positive for antibodies against hepatitis D virus. All HIV/HBVcoinfected patients were receiving drugs with activity against HBV, and 97% of those tested for HBV DNA had an HBV DNA load < 80 IU/mL. Conclusions: The prevalence of HIV/HBV coinfection in Spain remained stable at around 3% for a decade. Our data could facilitate the design of national programmes to control HBV infection and help identify areas of patient management that need improvement.
  • Others:

    Author, as appears in the article.: Perez-Latorre, Leire; Berenguer, Juan; Mican, Rafael; Montero, Marta; Cifuentes, Carmen; Puig, Teresa; Sanz, Jose; Ferrero, Oscar L.; de la Fuente, Belen; Rodriguez, Carmen; Reus, Sergio; Hernandez-Quero, Jose; Gaspar, Gabriel; Perez-Martinez, Laura; Garcia, Coral; Force, Luis; Veloso, Sergio; De Miguel, Marta; Jarrin, Inmaculada; Gonzalez-Garcia, Juan;Gesida Study Grp
    Department: Medicina i Cirurgia
    URV's Author/s: PERAIRE FORNER, JOSÉ JOAQUIN
    Keywords: Prevalence Mortality Impact Immunodeficiency Hepatitis-b Hcv Clearance B-virus coinfection Antiretroviral therapy
    Abstract: Background: Recent and reliable estimates on the prevalence of coinfection with human immunodeficiency virus (HIV) and hepatitis B virus (HBV) in Europe are lacking. Aim: Leveraged on a study designed to assess HIV/HCV coinfection prevalence, we assessed the prevalence of HIV/HBV coinfection in Spain in 2018 and compared the results with five similar studies performed since 2002. Methods: This cross-sectional prevalence study was carried out in 43 centres, and patients were selected using simple random sampling. The reference population comprised 40,322 patients and the sample size were 1,690 patients. Results: The prevalence of HIV/HBV coinfection in Spain at the end of 2018 was 3.2%. The prevalence in 2002, 2009, 2015, 2016 and 2017 was 4.9%, 3.4%, 3%, 3.9% and 3%, respectively. Among the HIV/HBV-coinfected patients identified in 2018, 16.7% had cirrhosis according to transient elastography and 26.3% tested positive for antibodies against hepatitis D virus. All HIV/HBVcoinfected patients were receiving drugs with activity against HBV, and 97% of those tested for HBV DNA had an HBV DNA load < 80 IU/mL. Conclusions: The prevalence of HIV/HBV coinfection in Spain remained stable at around 3% for a decade. Our data could facilitate the design of national programmes to control HBV infection and help identify areas of patient management that need improvement.
    Thematic Areas: Virology Saúde coletiva Public health, environmental and occupational health Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Infectious diseases General medicine Farmacia Epidemiology Ciências biológicas iii Ciências agrárias i Biotecnología
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: joaquim.peraire@urv.cat
    Author identifier: 0000-0001-7808-5479
    Record's date: 2021-10-10
    Papper version: info:eu-repo/semantics/publishedVersion
    Papper original source: Eurosurveillance. 26 (25):
    APA: Perez-Latorre, Leire; Berenguer, Juan; Mican, Rafael; Montero, Marta; Cifuentes, Carmen; Puig, Teresa; Sanz, Jose; Ferrero, Oscar L.; de la Fuente, Be (2021). HIV/HBV coinfection: temporal trends and patient characteristics, Spain, 2002 to 2018. Eurosurveillance, 26(25), -. DOI: 10.2807/1560-7917.ES.2021.26.25.2000236
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Epidemiology,Infectious Diseases,Medicine (Miscellaneous),Public Health, Environmental and Occupational Health,Virology
    Prevalence
    Mortality
    Impact
    Immunodeficiency
    Hepatitis-b
    Hcv
    Clearance
    B-virus coinfection
    Antiretroviral therapy
    Virology
    Saúde coletiva
    Public health, environmental and occupational health
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina ii
    Medicina i
    Infectious diseases
    General medicine
    Farmacia
    Epidemiology
    Ciências biológicas iii
    Ciências agrárias i
    Biotecnología
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