Author, as appears in the article.: Bonet, Gil; Carrasquer, Anna; Peiro, Oscar M.; Sanchez-Gimenez, Raul; Lal-Trehan, Nisha; del-Moral-Ronda, Victor; Fort-Gallifa, Isabel; Bardaji, Alfredo;
Department: Medicina i Cirurgia
URV's Author/s: Bardají Ruiz, Alfredo / Bonet Pineda, Gil / Carrasquer Cucarella, Ana Maria / Peiró Ibáñez, Óscar Manuel / Sánchez Giménez, Raúl
Keywords: Type-2 Troponin i Time factors Spain Risk factors Risk assessment Risk Retrospective studies Prognosis Prevention Patient readmission Patient admission Outcomes Myocardial injury Myocardial infarction Mortality Middle aged Mellitus Male Humans Heart failure Female Emergency service, hospital Disease progression Diabetes mellitus Diabetes Cardiovascular-disease Cardiac troponin-t Cardiac troponin Biomarkers Aged, 80 and over Aged Adults
Abstract: Background This study aimed to investigate the clinical features and prognosis of diabetes and myocardial injury in patients admitted to the emergency department. Methods We analyzed the clinical data of all consecutive patients admitted to the emergency department during the years 2012 and 2013 with at least 1 cardiac Troponin I (cTnI Ultra Siemens, Advia Centaur) determination, and were classified according to the status of diabetes mellitus (DM) and myocardial injury (MI). Clinical events were evaluated in a 4-year follow-up. Results A total of 3622 patients were classified according to the presence of DM (n = 924 (25.55%)) and MI (n = 1049 (28.96%)). The proportion of MI in patients with DM was 40% and 25% in patients without DM. Mortality during follow-up was 10.9% in non-DM patients without MI, 21.3% in DM patients without MI, 40.1% in non-DM patients with MI, and 52.8% in DM patients with MI. A competitive risk model was used to obtain the Hazard Ratio (HR) for readmission for myocardial infarction or heart failure. There was a similar proportion of readmission for myocardial infarction and heart failure at a four-year follow-up in patients with DM or MI, which was much higher when DM was associated with MI, with respect to patients without DM or MI. The HR (95% Coefficient Interval) for myocardial infarction in the DM without MI, non-DM with MI, and DM with MI groups with respect to the non-DM without MI group was 2511 (1592-3960), 2682 (1739-4138), and 5036 (3221-7876), respectively. The HR (95% CI) for the risk of readmission for heart failure in the DM without MI, non-DM with MI, and DM with MI groups with respect to the non-DM without MI group was 2663 (1825-3886), 2562 (1753-3744) and 4292 (2936-6274), respectively. Conclusions The association of DM and MI in patients treated in an Emergency Service identifies patients at very high risk of mortality and cardiovascular events.
Thematic Areas: Saúde coletiva Psicología Medicina iii Medicina ii Medicina i Matemática / probabilidade e estatística Interdisciplinar Farmacia Educação física Ciências biológicas ii Ciências biológicas i Cardiology and cardiovascular medicine Cardiac & cardiovascular systems Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 1471-2261
Author's mail: gil.bonet@urv.cat oscarmanuel.peiro@urv.cat anamaria.carrasquer@urv.cat raul.sanchez@estudiants.urv.cat oscarmanuel.peiro@urv.cat anamaria.carrasquer@urv.cat alfredo.bardaji@urv.cat
Author identifier: 0000-0003-1900-6974
Record's date: 2024-08-03
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-021-02220-1
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Bmc Cardiovascular Disorders. 21 (1): 414-
APA: Bonet, Gil; Carrasquer, Anna; Peiro, Oscar M.; Sanchez-Gimenez, Raul; Lal-Trehan, Nisha; del-Moral-Ronda, Victor; Fort-Gallifa, Isabel; Bardaji, Alfre (2021). Clinical characteristics and prognostic implications of diabetes and myocardial injury in patients admitted to the emergency room. Bmc Cardiovascular Disorders, 21(1), 414-. DOI: 10.1186/s12872-021-02220-1
Article's DOI: 10.1186/s12872-021-02220-1
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications
Repositori URV