Articles producció científica> Química Física i Inorgànica

Paper-based plasmonic substrates as surface-enhanced Raman scattering spectroscopy platforms for cell culture applications

  • Identification data

    Identifier: imarina:9228400
    Authors:
    Romo-Herrera, J. M.Juarez-Moreno, K.Guerrini, L.Kang, Y.Feliu, N.Parak, W. J.Alvarez-Puebla, R. A.
    Abstract:
    The engineering of advanced materials capable of mimicking the cellular micro-environment while providing cells with physicochemical cues is central for cell culture applications. In this regard, paper meets key requirements in terms of biocompatibility, hydrophilicity, porosity, mechanical strength, ease of physicochemical modifications, cost, and ease of large-scale production, to be used as a scaffold material for biomedical applications. Most notably, paper has demonstrated the potential to become an attractive alternative to conventional biomaterials for creating two-dimensional (2D) and three-dimensional (3D) biomimetic cell culture models that mimic the features of in vivo tissue environments for improving our understanding of cell behavior (e.g. growth, cell migration, proliferation, differentiation and tumor metastasis) in their natural state. On the other hand, integration of plasmonic nanomaterials (e.g. gold nanoparticles) within the fibrous structure of paper opens the possibility to generate multifunctional scaffolds equipped with biosensing tools for monitoring different cell cues through physicochemical signals. Among different plasmonic based detection techniques, surface-enhanced Raman scattering (SERS) spectroscopy emerged as a highly specific and sensitive optical tool for its extraordinary sensitivity and the ability for multidimensional and accurate molecular identification. Thus, paper-based plasmonic substrates in combination with SERS optical detection represent a powerful future platform for monitoring cell cues during cell culture processes. To this end, in this review, we will describe the different methods for fabricating hybrid paper-plasmonic nanoparticle substrates and their use in combination with SERS spectroscopy for biosensing and, mo
  • Others:

    Author, as appears in the article.: Romo-Herrera, J. M.; Juarez-Moreno, K.; Guerrini, L.; Kang, Y.; Feliu, N.; Parak, W. J.; Alvarez-Puebla, R. A.;
    Department: Química Física i Inorgànica
    URV's Author/s: Alvarez Puebla, Ramon Angel / Guerrini, Luca
    Keywords: Silver nanoparticles Sers substrate Sers Separation Scaffolds Plasmonic papers Plasmonic nanoparticles Paper-based substrates Gold nanoparticles Fabrication Coated filter-paper Cellulose Cell culture Biomaterials Adsorption
    Abstract: The engineering of advanced materials capable of mimicking the cellular micro-environment while providing cells with physicochemical cues is central for cell culture applications. In this regard, paper meets key requirements in terms of biocompatibility, hydrophilicity, porosity, mechanical strength, ease of physicochemical modifications, cost, and ease of large-scale production, to be used as a scaffold material for biomedical applications. Most notably, paper has demonstrated the potential to become an attractive alternative to conventional biomaterials for creating two-dimensional (2D) and three-dimensional (3D) biomimetic cell culture models that mimic the features of in vivo tissue environments for improving our understanding of cell behavior (e.g. growth, cell migration, proliferation, differentiation and tumor metastasis) in their natural state. On the other hand, integration of plasmonic nanomaterials (e.g. gold nanoparticles) within the fibrous structure of paper opens the possibility to generate multifunctional scaffolds equipped with biosensing tools for monitoring different cell cues through physicochemical signals. Among different plasmonic based detection techniques, surface-enhanced Raman scattering (SERS) spectroscopy emerged as a highly specific and sensitive optical tool for its extraordinary sensitivity and the ability for multidimensional and accurate molecular identification. Thus, paper-based plasmonic substrates in combination with SERS optical detection represent a powerful future platform for monitoring cell cues during cell culture processes. To this end, in this review, we will describe the different methods for fabricating hybrid paper-plasmonic nanoparticle substrates and their use in combination with SERS spectroscopy for biosensing and, more specifically, in cell culture applications.
    Thematic Areas: Molecular biology Materials science, biomaterials Engineering, biomedical Cell biology Biotechnology Biomedical engineering Biomaterials Bioengineering
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: ramon.alvarez@urv.cat luca.guerrini@urv.cat
    Author identifier: 0000-0003-4770-5756 0000-0002-2925-1562
    Record's date: 2024-07-27
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.sciencedirect.com/science/article/pii/S2590006421000338
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Materials Today Bio. 11
    APA: Romo-Herrera, J. M.; Juarez-Moreno, K.; Guerrini, L.; Kang, Y.; Feliu, N.; Parak, W. J.; Alvarez-Puebla, R. A.; (2021). Paper-based plasmonic substrates as surface-enhanced Raman scattering spectroscopy platforms for cell culture applications. Materials Today Bio, 11(), -. DOI: 10.1016/j.mtbio.2021.100125
    Article's DOI: 10.1016/j.mtbio.2021.100125
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Bioengineering,Biomaterials,Biomedical Engineering,Biotechnology,Cell Biology,Engineering, Biomedical,Materials Science, Biomaterials,Molecular Biology
    Silver nanoparticles
    Sers substrate
    Sers
    Separation
    Scaffolds
    Plasmonic papers
    Plasmonic nanoparticles
    Paper-based substrates
    Gold nanoparticles
    Fabrication
    Coated filter-paper
    Cellulose
    Cell culture
    Biomaterials
    Adsorption
    Molecular biology
    Materials science, biomaterials
    Engineering, biomedical
    Cell biology
    Biotechnology
    Biomedical engineering
    Biomaterials
    Bioengineering
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