Articles producció científica> Bioquímica i Biotecnologia

Historical Review of Studies on Sacroiliac Fatty Nodules (Recently Termed "Back Mice") as a Potential Cause of Low Back Pain

  • Identification data

    Identifier: imarina:9228570
    Authors:
    Canis Parera, MartaExposito Izquierdo, MartaCabre Vila, Juan Jose
    Abstract:
    Low back pain is a widespread and poorly understood condition that is frequently diagnosed as non-specific low back pain. We were intrigued by the presence of painful sacroiliac nodules in patients with this condition. We conducted a historical review to elucidate this relationship. This chronicled review summarizes the overlooked literature from different countries, especially from around the 1950s, regarding the diagnosis and management of these painful nodules. Biopsies have confirmed the adipose nature of these nodules and revealed distinct pathological signs, including oedema and fascial fatty herniation. Studies have suggested both intra-nodule local anaesthetic injection and surgery as successful treatments for managing pain on a short- or long-term basis. Recent ultrasound studies have confirmed these findings. The various terms used for these nodules over time are specifically described. We conclude that it may be necessary to reconsider the role of fatty tissue in the aetiology and treatment of low back pain in today's mainstream medicine. This could lead to advances in understanding unexplained musculoskeletal pain disorders beyond low back pain. Meanwhile, despite the remaining questions, the treatments identified in these studies can help physicians manage patients' unresolved pain. We recommend that future research use this review as a foundation for further study.
  • Others:

    Author, as appears in the article.: Canis Parera, Marta; Exposito Izquierdo, Marta; Cabre Vila, Juan Jose;
    Department: Bioquímica i Biotecnologia
    URV's Author/s: Cabre Vila, Juan Jose / Cañis Parera, Marta / Exposito Izquierdo, Marta
    Keywords: Ultrasound Thermogenesis Systematic review Subfascial fat herniation Subfascial fat Strangulation Sacroiliitis Review Recanalization Painful fatty nodules Ovary cyst Osteoarthritis Nuclear magnetic resonance imaging Nonhuman Nonarticular rheumatism Non-specific low back pain Non-articular rheumatism Neck pain Myofascial pain Low back pain Liposarcoma Lipoma Lipid storage Lecture Intervertebral disk hernia Inflammation Human Herniation Headache Fluid retention Fibrositis Fibromyalgia Edema Echography Constipation Bloating Backache Back mice Adipose tissue
    Abstract: Low back pain is a widespread and poorly understood condition that is frequently diagnosed as non-specific low back pain. We were intrigued by the presence of painful sacroiliac nodules in patients with this condition. We conducted a historical review to elucidate this relationship. This chronicled review summarizes the overlooked literature from different countries, especially from around the 1950s, regarding the diagnosis and management of these painful nodules. Biopsies have confirmed the adipose nature of these nodules and revealed distinct pathological signs, including oedema and fascial fatty herniation. Studies have suggested both intra-nodule local anaesthetic injection and surgery as successful treatments for managing pain on a short- or long-term basis. Recent ultrasound studies have confirmed these findings. The various terms used for these nodules over time are specifically described. We conclude that it may be necessary to reconsider the role of fatty tissue in the aetiology and treatment of low back pain in today's mainstream medicine. This could lead to advances in understanding unexplained musculoskeletal pain disorders beyond low back pain. Meanwhile, despite the remaining questions, the treatments identified in these studies can help physicians manage patients' unresolved pain. We recommend that future research use this review as a foundation for further study.
    Thematic Areas: Neurology (clinical) Clinical neurology Anesthesiology and pain medicine
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: juanjose.cabre@urv.cat marta.canis@estudiants.urv.cat marta.exposito@estudiants.urv.cat
    Author identifier: 0000-0003-1082-6861 0000-0001-5071-7745
    Record's date: 2024-07-27
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://link.springer.com/article/10.1007/s40122-021-00321-5
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Pain Ther. 10 (2): 1029-1050
    APA: Canis Parera, Marta; Exposito Izquierdo, Marta; Cabre Vila, Juan Jose; (2021). Historical Review of Studies on Sacroiliac Fatty Nodules (Recently Termed "Back Mice") as a Potential Cause of Low Back Pain. Pain Ther, 10(2), 1029-1050. DOI: 10.1007/s40122-021-00321-5
    Article's DOI: 10.1007/s40122-021-00321-5
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Anesthesiology and Pain Medicine,Clinical Neurology,Neurology (Clinical)
    Ultrasound
    Thermogenesis
    Systematic review
    Subfascial fat herniation
    Subfascial fat
    Strangulation
    Sacroiliitis
    Review
    Recanalization
    Painful fatty nodules
    Ovary cyst
    Osteoarthritis
    Nuclear magnetic resonance imaging
    Nonhuman
    Nonarticular rheumatism
    Non-specific low back pain
    Non-articular rheumatism
    Neck pain
    Myofascial pain
    Low back pain
    Liposarcoma
    Lipoma
    Lipid storage
    Lecture
    Intervertebral disk hernia
    Inflammation
    Human
    Herniation
    Headache
    Fluid retention
    Fibrositis
    Fibromyalgia
    Edema
    Echography
    Constipation
    Bloating
    Backache
    Back mice
    Adipose tissue
    Neurology (clinical)
    Clinical neurology
    Anesthesiology and pain medicine
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