Author, as appears in the article.: Lopez, Beatriz; Torrent-Fontbona, Ferran; Masana Marin, Luis; Zamora, Alberto;
Department: Medicina i Cirurgia
URV's Author/s: Masana Marín, Luis
Keywords: Tool Risk Medication Lowering treatment Knowledge-based systems Hypercholesterolemia detection Guideline Efficacy Dyslipidemia treatment Disease Decision-support-system Clinical decision support systems Cholesterol management
Abstract: HTE 3.0 aims to support clinicians in the detection of patients with dyslipidemia, especially patients with familial hypercholesterolemia (FH), and in the recommendation of personalized lipid-lowering treatments. The core of HTE 3.0 is a clinical decision support system in which several knowledge-based systems are serialized: patient detection, therapeutic target setting, personalized treatment assessment, and treatment combination and prioritization, according to different criteria. The experimental evaluation of HTE 3.0 shows that the use of HTE 3.0 would mean increasing the capacity to detect FH by 5.7 times compared with usual clinical practice. Regarding the lipid-lowering treatment, a comparison of 18 cases among seven lipidologists shows that the differences between treatments provided by HTE 3.0 and human lipidologists are smaller than the differences between human experts.
Thematic Areas: Theoretical computer science Engenharias iii Control and systems engineering Computer science, theory & methods Computer science, artificial intelligence Computational theory and mathematics Ciência da computação Artificial intelligence Administração pública e de empresas, ciências contábeis e turismo
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: luis.masana@urv.cat
Author identifier: 0000-0002-0789-4954
Record's date: 2024-09-07
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://onlinelibrary.wiley.com/doi/full/10.1111/exsy.12835
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Expert Systems. 39 (1):
APA: Lopez, Beatriz; Torrent-Fontbona, Ferran; Masana Marin, Luis; Zamora, Alberto; (2022). HTE 3.0: Knowledge-based systems in cascade for familial hypercholesterolemia detection and dyslipidemia treatment. Expert Systems, 39(1), -. DOI: 10.1111/exsy.12835
Article's DOI: 10.1111/exsy.12835
Entity: Universitat Rovira i Virgili
Journal publication year: 2022
Publication Type: Journal Publications
Repositori URV