Author, as appears in the article.: Gutierrez L; Folch A; Rojas M; Cantero JL; Atienza M; Folch J; Camins A; Ruiz A; Papandreou C; Bulló M
Department: Bioquímica i Biotecnologia
URV's Author/s: Bulló Bonet, Mònica / Folch Lopez, Jaume / Gutiérrez Victoriano, Luis / Rojas Criollo, Melina Isabella / RUIZ GUILLÉN, ANTONIO
Keywords: Supplements Subjective cognitive decline Placebo-controlled trial Healthy Food Dietary interventions Diet Cognitive impairment Alzheimer’s disease supplements subjective cognitive decline polyunsaturated fatty-acids older-adults multidomain intervention memory mediterranean diet healthy food fish-oil double-blind dietary interventions decline cognitive impairment brain alzheimer's disease
Abstract: New dietary approaches for the prevention of cognitive impairment are being investigated. However, evidence from dietary interventions is mainly from food and nutrient supplement interventions, with inconsistent results and high heterogeneity between trials. We conducted a comprehensive systematic search of randomized controlled trials (RCTs) published in MEDLINE-Pub- Med, from January 2018 to July 2021, investigating the impact of dietary counseling, as well as food-based and dietary supplement interventions on cognitive function in adults with or without cognitive impairment. Based on the search strategy, 197 eligible publications were used for data abstraction. Finally, 61 articles were included in the analysis. There was reasonable evidence that dietary patterns, as well as food and dietary supplements improved cognitive domains or measures of brain integrity. The Mediterranean diet showed promising results, whereas the role of the DASH diet was not clear. Healthy food consumption improved cognitive function, although the quality of these studies was relatively low. The role of dietary supplements was mixed, with strong evidence of the benefits of polyphenols and combinations of nutrients, but with low evidence for PUFAs, vitamin D, specific protein, amino acids, and other types of supplements. Further well-designed RCTs are needed to guide the development of dietary approaches for the prevention of cognitive impairment.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: jaume.folch@urv.cat monica.bullo@urv.cat luis.gutierrez@estudiants.urv.cat melina.rojas@estudiants.urv.cat
Author identifier: 0000-0002-5051-8858 0000-0002-0218-7046
Record's date: 2024-06-22
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2072-6643/13/11/3728
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Nutrients. 13 (11):
APA: Gutierrez L; Folch A; Rojas M; Cantero JL; Atienza M; Folch J; Camins A; Ruiz A; Papandreou C; Bulló M (2021). Effects of nutrition on cognitive function in adults with or without cognitive impairment: A systematic review of randomized controlled clinical trials. Nutrients, 13(11), -. DOI: 10.3390/nu13113728
Article's DOI: 10.3390/nu13113728
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications
Repositori URV