Articles producció científica> Bioquímica i Biotecnologia

Effects of nutrition on cognitive function in adults with or without cognitive impairment: A systematic review of randomized controlled clinical trials

  • Identification data

    Identifier: imarina:9230637
    Authors:
    Gutierrez, LaiaFolch, AlexandreRojas, MelinaCantero, Jose LuisAtienza, MercedesFolch, JaumeCamins, AntoniRuiz, AgustinPapandreou, ChristopherBullo, Monica
    Abstract:
    New dietary approaches for the prevention of cognitive impairment are being investigated. However, evidence from dietary interventions is mainly from food and nutrient supplement interventions, with inconsistent results and high heterogeneity between trials. We conducted a comprehensive systematic search of randomized controlled trials (RCTs) published in MEDLINE-Pub- Med, from January 2018 to July 2021, investigating the impact of dietary counseling, as well as food-based and dietary supplement interventions on cognitive function in adults with or without cognitive impairment. Based on the search strategy, 197 eligible publications were used for data abstraction. Finally, 61 articles were included in the analysis. There was reasonable evidence that dietary patterns, as well as food and dietary supplements improved cognitive domains or measures of brain integrity. The Mediterranean diet showed promising results, whereas the role of the DASH diet was not clear. Healthy food consumption improved cognitive function, although the quality of these studies was relatively low. The role of dietary supplements was mixed, with strong evidence of the benefits of polyphenols and combinations of nutrients, but with low evidence for PUFAs, vitamin D, specific protein, amino acids, and other types of supplements. Further well-designed RCTs are needed to guide the development of dietary approaches for the prevention of cognitive impairment.
  • Others:

    Author, as appears in the article.: Gutierrez, Laia; Folch, Alexandre; Rojas, Melina; Cantero, Jose Luis; Atienza, Mercedes; Folch, Jaume; Camins, Antoni; Ruiz, Agustin; Papandreou, Christopher; Bullo, Monica
    Department: Bioquímica i Biotecnologia
    URV's Author/s: Bulló Bonet, Mònica / Folch Lopez, Jaume / Gutiérrez Victoriano, Luis / Rojas Criollo, Melina Isabella / RUIZ GUILLÉN, ANTONIO
    Keywords: Vitamins Supplements Subjective cognitive decline Sample size Risk Randomized controlled trials as topic Publication bias Polyphenols Placebo-controlled trial Nutrients Humans Healthy Food Fatty acids, unsaturated Dietary supplements Dietary interventions Diet Counseling Cognitive impairment Cognitive dysfunction Cognition Alzheimer’s disease Adult supplements subjective cognitive decline polyunsaturated fatty-acids older-adults multidomain intervention memory mediterranean diet healthy food fish-oil double-blind dietary interventions decline cognitive impairment brain alzheimer's disease
    Abstract: New dietary approaches for the prevention of cognitive impairment are being investigated. However, evidence from dietary interventions is mainly from food and nutrient supplement interventions, with inconsistent results and high heterogeneity between trials. We conducted a comprehensive systematic search of randomized controlled trials (RCTs) published in MEDLINE-Pub- Med, from January 2018 to July 2021, investigating the impact of dietary counseling, as well as food-based and dietary supplement interventions on cognitive function in adults with or without cognitive impairment. Based on the search strategy, 197 eligible publications were used for data abstraction. Finally, 61 articles were included in the analysis. There was reasonable evidence that dietary patterns, as well as food and dietary supplements improved cognitive domains or measures of brain integrity. The Mediterranean diet showed promising results, whereas the role of the DASH diet was not clear. Healthy food consumption improved cognitive function, although the quality of these studies was relatively low. The role of dietary supplements was mixed, with strong evidence of the benefits of polyphenols and combinations of nutrients, but with low evidence for PUFAs, vitamin D, specific protein, amino acids, and other types of supplements. Further well-designed RCTs are needed to guide the development of dietary approaches for the prevention of cognitive impairment.
    Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: melina.rojas@estudiants.urv.cat luis.gutierrez@estudiants.urv.cat monica.bullo@urv.cat jaume.folch@urv.cat
    Author identifier: 0000-0002-0218-7046 0000-0002-5051-8858
    Record's date: 2024-10-12
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.mdpi.com/2072-6643/13/11/3728
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Nutrients. 13 (11): 3728-
    APA: Gutierrez, Laia; Folch, Alexandre; Rojas, Melina; Cantero, Jose Luis; Atienza, Mercedes; Folch, Jaume; Camins, Antoni; Ruiz, Agustin; Papandreou, Chri (2021). Effects of nutrition on cognitive function in adults with or without cognitive impairment: A systematic review of randomized controlled clinical trials. Nutrients, 13(11), 3728-. DOI: 10.3390/nu13113728
    Article's DOI: 10.3390/nu13113728
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2021
    Publication Type: Journal Publications
  • Keywords:

    Food Science,Nutrition & Dietetics,Nutrition and Dietetics
    Vitamins
    Supplements
    Subjective cognitive decline
    Sample size
    Risk
    Randomized controlled trials as topic
    Publication bias
    Polyphenols
    Placebo-controlled trial
    Nutrients
    Humans
    Healthy
    Food
    Fatty acids, unsaturated
    Dietary supplements
    Dietary interventions
    Diet
    Counseling
    Cognitive impairment
    Cognitive dysfunction
    Cognition
    Alzheimer’s disease
    Adult
    supplements
    subjective cognitive decline
    polyunsaturated fatty-acids
    older-adults
    multidomain intervention
    memory
    mediterranean diet
    healthy
    food
    fish-oil
    double-blind
    dietary interventions
    decline
    cognitive impairment
    brain
    alzheimer's disease
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Psicología
    Planejamento urbano e regional / demografia
    Nutrition and dietetics
    Nutrition & dietetics
    Nutrição
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    Food science
    Farmacia
    Engenharias iv
    Engenharias ii
    Enfermagem
    Educação física
    Economia
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Biotecnología
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