Association between the Prime Diet Quality Score and depressive symptoms in a Mediterranean population with metabolic syndrome. Cross-sectional and 2-year follow-up assessment from PREDIMED-PLUS study

Author, as appears in the article.: Cano-Ibanez, Naomi; Serra-Majem, Lluis; Martin-Pelaez, Sandra; Angel Martinez-Gonzalez, Miguel; Salas-Salvado, Jordi; Corella Piquer, Maria Dolores; Lassale, Camille; Martinez Hernandez, Jose Alfredo; Alonso-Gomez, Angel M; Warnberg, Julia; Vioque Lopez, Jesus; Romaguera, Dora; Lopez-Miranda, Jose; Estruch, Ramon; Maria Gomez-Perez, Ana; Manuel Santos-Lozano, Jose; Fernandez-Aranda, Fernando; Bueno-Cavanillas, Aurora; Tur, Josep A; Martin, Vicente; Pinto Sala, Xavier; Delgado-Rodriguez, Miguel; Matia Martin, Pilar; Vidal, Josep; Cardenas, Jersy J; Daimiel Ruiz, Lidia; Ros, Emilio; Buil-Cosiales, Pilar; Becerra-Tomas, Nerea; Saiz, Carmen; Munoz-Perez, Miguel-Angel; Abete, Itziar; Tojal-Sierra, Lucas; Fernandez-Barcelo, Olga; Bernabe-Casanova, Andrea; Konieczna, Jadwiga; Garcia-Rios, Antonio; Casas, Rosa; Rosa Bernal-Lopez, Maria; Lapetra, Jose; Toledo, Estefania; Gomez-Martinez, Carlos; Coltell, Oscar; Malcampo-Manrubia, Mireia; Angeles Zulet, Maria; Sorto-Sanchez, Carolina; Gea, Alfredo; Luis Hernandez-Fleta, Jose; Castaner Nino, Olga; Sanchez-Villegas, Almudena

Department: Bioquímica i Biotecnologia

URV's Author/s: Becerra Tomás, Nerea / GOMEZ ALONSO, CRISTINA / Salas Salvadó, Jorge

Keywords: Prime diet quality score; Predimed-plus study; Metabolic syndrome; Humans; Follow-up studies; Diet, mediterranean; Diet; Depressive symptomatology; Depression; Cross-sectional studies; Aged

Abstract: The burden of depression is increasing worldwide, specifically in older adults. Unhealthy dietary patterns may partly explain this phenomenon. In the Spanish PREDIMED-Plus study we explored (1) the cross-sectional association between the adherence to the Prime Diet Quality Score- (PDQS), an a priori-defined high-quality food pattern and the prevalence of depressive symptoms at baseline (cross-sectional analysis), and (2) the prospective association of baseline PDQS with changes in depressive symptomatology after 2 years of follow-up. After exclusions, we assessed 6612 participants in the cross-sectional analysis and 5523 participants in the prospective analysis. An energy-adjusted high-quality dietary score (PDQS) was assessed using a validated food-frequency questionnaire (FFQ). The cross-sectional association between PDQS and the prevalence of depression, presence of depressive symptoms and prospectively assessed changes in depressive symptoms was evaluated through multivariable regression models (logistic and linear models and mixed linear-effects models). PDQS was inversely associated with depressive status in the cross-sectional analysis. Participants in the highest quintile of PDQS (Q5) showed a significantly reduced odds of depression prevalence as compared to participants in the lowest quartile of PDQS (Q1) [OR (95%) CI= 0.82 (0.68, 0.98))]. The baseline prevalence of depression decreased across PDQS quintiles (p for trend=0.015). A statistically significant association between PDQS and changes in depressive symptoms after 2-y follow-up was found (β (95%) CI = -0.67 z-score (-1.17, -0.18). A higher PDQS was cross-sectionally related to a lower depressive status. Nevertheless, the null finding in our prospective analysis, raises the possibility of reverse causality. Further prospective investigation is required to ascertain the association between PDQS and changes in depressive symptoms along time.

Thematic Areas: Zootecnia / recursos pesqueiros; Saúde coletiva; Química; Odontología; Nutrition and dietetics; Nutrition & dietetics; Nutrição; Medicine (miscellaneous); Medicina veterinaria; Medicina iii; Medicina ii; Medicina i; Matemática / probabilidade e estatística; Interdisciplinar; General medicine; Farmacia; Engenharias iv; Engenharias ii; Educação física; Ciências biológicas iii; Ciências biológicas ii; Ciências biológicas i; Ciências ambientais; Ciências agrárias i; Ciência de alimentos; Biotecnología; Biodiversidade; Administração pública e de empresas, ciências contábeis e turismo

licence for use: https://creativecommons.org/licenses/by/3.0/es/

Author's mail: nerea.becerra@urv.cat; jordi.salas@urv.cat

Record's date: 2025-02-08

Paper version: info:eu-repo/semantics/acceptedVersion

Link to the original source: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/abs/association-between-the-prime-diet-quality-score-and-depressive-symptoms-in-a-mediterranean-population-with-metabolic-syndrome-crosssectional-and-2year-followup-assessment-from-predimedplus-study/D8DCCF247EA97D1AAC040C4A4D1C89D3#

Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/

Paper original source: British Journal Of Nutrition. 128 (6): 1-25

APA: Cano-Ibanez, Naomi; Serra-Majem, Lluis; Martin-Pelaez, Sandra; Angel Martinez-Gonzalez, Miguel; Salas-Salvado, Jordi; Corella Piquer, Maria Dolores; L (2022). Association between the Prime Diet Quality Score and depressive symptoms in a Mediterranean population with metabolic syndrome. Cross-sectional and 2-year follow-up assessment from PREDIMED-PLUS study. British Journal Of Nutrition, 128(6), 1-25. DOI: 10.1017/s0007114521004323

Article's DOI: 10.1017/s0007114521004323

Entity: Universitat Rovira i Virgili

Journal publication year: 2022

Publication Type: Journal Publications