Author, as appears in the article.: Álvarez?uría A; Escribano P; Parra?blanco V; Cano?lira JF; Stchigel AM; Oarbeascoa G; Muñoz P; Guinea J
Department: Ciències Mèdiques Bàsiques
URV's Author/s: Cano Lira, José Francisco / Stchigel Glikman, Alberto Miguel
Keywords: Neutropenia Molecular identification Invasive fungal infection Diagnosis Cephalotrichum gorgonifer Cell transplant recipients neutropenia molecular identification invasive fungal infection epidemiology diagnosis
Abstract: The etiological agents of infrequent invasive fungal infections (IFI) are difficult to identify on the species level using classic morphological examination. We describe the first case of an IFI caused by Cephalotrichum gorgonifer in a neutropenic patient with a hematological malignancy and put it on the map as a new causative agent of IFI. Case report, microbiological findings and description of the etiological agent. A 60?year?old man was diagnosed with mantle cell lymphoma. A CT scan confirmed the presence of lung infiltrates located at the right upper lobe. Histological examination of one of the nodules showed a large number of narrow septate hyphae with acute?angle branching and irregular round cell morphology; vessels walls appeared infiltrated, proving an angioinvasive pulmonary IFI. Sample culture resulted positive and molecular identification proved the presence of Cephalotrichum gorgonifer. Voriconazole was used for 12 months and the patient did not report any complications or side effects. Complete remission of lymphoma was achieved later by the time chemotherapy, radiotherapy, and radioimmunotherapy consolidation were completed. We recommend the inclusion of Cephalotrichum gorgonifer in the list of opportunistic pathogens causing mycoses in neutropenic hematological patients with suspected mould?related IFI. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Thematic Areas: Plant science Mycology Microbiology (medical) Microbiology Farmacia Ecology, evolution, behavior and systematics Ciências biológicas iii Ciências biológicas ii
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: jose.cano@urv.cat albertomiguel.stchigel@urv.cat
Author identifier: 0000-0003-4495-4394 0000-0003-3987-7996
Record's date: 2023-02-19
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2309-608X/7/12/1089
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: J Fungi (Basel). 7 (12):
APA: Álvarez?uría A; Escribano P; Parra?blanco V; Cano?lira JF; Stchigel AM; Oarbeascoa G; Muñoz P; Guinea J (2021). First report of an invasive infection by cephalotrichum gorgonifer in a neutropenic patient with hematological malignancy under chemotherapy. J Fungi (Basel), 7(12), -. DOI: 10.3390/jof7121089
Article's DOI: 10.3390/jof7121089
Entity: Universitat Rovira i Virgili
Journal publication year: 2021
Publication Type: Journal Publications
Repositori URV