Author, as appears in the article.: Muñoz-Hernando J; Escribano J; Ferré N; Closa-Monasterolo R; Grote V; Koletzko B; Gruszfeld D; ReDionigi A; Verduci E; Xhonneux A; Luque V
Department: Medicina i Cirurgia
URV's Author/s: Closa Monasterolo, Ricardo / Escribano Subías, Joaquín / Ferre Pallas, Natalia / Luque Moreno, Verònica / Muñoz Hernando, Judit
Keywords: Waist-to-height ratio Metabolic syndrome Childhood obesity Cardiovascular risk Body-mass index Abdominal obesity young-children weight waist-to-height ratio metabolic syndrome insulin european children circumference cardiovascular risk association adolescents abdominal obesity
Abstract: Background & aims: Only limited information is available on the usefulness of the waist-to-height ratio (WHtR) as an abdominal obesity marker in children. Our aim was to compare the ability of a WHtR >90th percentile, a WHtR ≥0.50, a WHtR ≥0.55 and a BMI z-score ≥2 SD to predict cardiometabolic risk in children followed-up at different ages. Methods: We evaluated data from 660 children at 5, 8 and 11 years of age who participated in the Childhood Obesity Project trial in 5 European countries. We classified children with or without cardiometabolic (CMet) risk (yes vs. no) according to the presence of ≥2 parameters (blood pressure, HOMA-IR, triglyceride levels and high-density lipoprotein (HDL) cholesterol levels) ≥90th percentile. Results: The odds ratio for CMet risk in children at all followed-up ages was statistically significant for all measures. The OR for the WHtR≥0.55 cut-off was 29.1 (5.6, 151.7) at 5 years of age, 11.8 (4.1, 33.8) at 8 year of age and 3.6 (1.7, 7.7) at 11 years of age, compared to the WHtR<0.55 cut-off. The WHtR≥0.55 cut-off showed a higher OR at younger ages than the BMI z-score ≥2SD, WHtR ≥90th percentile and WHtR≥0.50 cut-offs and a higher positive predictive value (82% at 5 years of age compared to 55%, 36% and 41%, respectively). Conclusion: A WHtR≥0.55 is a suitable cut-off for screening children at high cardiometabolic risk in the general young European population.
Thematic Areas: Saúde coletiva Química Odontología Nutrition and dietetics Nutrition & dietetics Nutrição Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Farmacia Engenharias iv Enfermagem Educação física Critical care and intensive care medicine Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: veronica.luque@urv.cat judit.munoz@urv.cat judit.munoz@urv.cat judit.munoz@urv.cat ricardo.closa@urv.cat natalia.ferre@urv.cat joaquin.escribano@urv.cat
Author identifier: 0000-0003-2615-8175 0000-0002-9963-4163 0000-0002-2838-1525 0000-0002-5041-459X
Record's date: 2024-09-21
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.clinicalnutritionjournal.com/article/S0261-5614(21)00557-4/fulltext
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Clinical Nutrition. 41 (2): 508-516
APA: Muñoz-Hernando J; Escribano J; Ferré N; Closa-Monasterolo R; Grote V; Koletzko B; Gruszfeld D; ReDionigi A; Verduci E; Xhonneux A; Luque V (2022). Usefulness of the waist-to-height ratio for predicting cardiometabolic risk in children and its suggested boundary values. Clinical Nutrition, 41(2), 508-516. DOI: 10.1016/j.clnu.2021.12.008
Article's DOI: 10.1016/j.clnu.2021.12.008
Entity: Universitat Rovira i Virgili
Journal publication year: 2022
Publication Type: Journal Publications
Repositori URV