Articles producció científica> Ciències Mèdiques Bàsiques

Omega-3 Fatty Acid Intake during Pregnancy and Child Neuropsychological Development: A  ulti-Centre Population-Based Birth Cohort Study in Spain

  • Identification data

    Identifier: imarina:9244541
    Authors:
    Tahaei HGignac FPinar AFernandez-Barrés SRomaguera DVioque JSanta-Marina LSubiza-Pérez MLlop SSoler-Blasco RArija VSalas-Salvadó JTardón ARiaño-Galán ISunyer JGuxens MJulvez J
    Abstract:
    Background: There are few studies that look at the intake of all types of omega-3 polyunsaturated fatty acids (n-3 PUFAs) during the different stages of pregnancy along with a long-term neuropsychological follow-up of the child. This study aims to explore the association between maternal n-3 PUFA intake during two periods of pregnancy and the child’s neuropsychological scores at different ages. Methods: Prospective data were obtained for 2644 pregnant women recruited between 2004 and 2008 in population-based birth cohorts in Spain. Maternal n-3 PUFA intake during the first and third trimester of pregnancy was estimated using validated food frequency questionnaires. Child neuropsychological functions were assessed using Bayley Scales of Infant Development version one (BSID) at 1 year old, the McCarthy Scale of Children’s Abilities (MSCA) at 4 years old, and the Attention Network Test (ANT) at 7 years old. Data were analysed using multivariate linear regression models and adjusted for potential covariates, such as maternal social class, education, cohort location, alcohol consumption, smoking, breastfeeding duration, and energy intake. Results: Compared to participants in the lowest quartile (<1.262 g/week) of n-3 PUFA consumption during the first trimester, those in the highest quartile (>1.657 g/week) had a 2.26 points (95% confidence interval (CI): 0.41, 4.11) higher MSCA general cognitive score, a 2.48 points (95% CI: 0.53, 4.43) higher MSCA verbal score, and a 2.06 points (95% CI: 0.166, 3.95) higher MSCA executive function score, and a 11.52 milliseconds (95% CI:-22.95,-0.09) lower ANT hit reaction time standard error. In the third pregnancy trimester, the associations were weaker. Conclusions: Positive associations between n-3 PUFA intake during early pregnancy and
  • Others:

    Author, as appears in the article.: Tahaei H; Gignac F; Pinar A; Fernandez-Barrés S; Romaguera D; Vioque J; Santa-Marina L; Subiza-Pérez M; Llop S; Soler-Blasco R; Arija V; Salas-Salvadó J; Tardón A; Riaño-Galán I; Sunyer J; Guxens M; Julvez J
    Department: Ciències Mèdiques Bàsiques Bioquímica i Biotecnologia
    URV's Author/s: Arija Val, Maria Victoria / Salas Salvadó, Jorge
    Keywords: Population-based cohort Polyunsaturated fatty-acids Omega-3 fatty acids Neurodevelopment Maternal diet Children seafood population-based cohort omega-3 fatty acids neurodevelopmental outcomes neurodevelopment energy diet consumption children
    Abstract: Background: There are few studies that look at the intake of all types of omega-3 polyunsaturated fatty acids (n-3 PUFAs) during the different stages of pregnancy along with a long-term neuropsychological follow-up of the child. This study aims to explore the association between maternal n-3 PUFA intake during two periods of pregnancy and the child’s neuropsychological scores at different ages. Methods: Prospective data were obtained for 2644 pregnant women recruited between 2004 and 2008 in population-based birth cohorts in Spain. Maternal n-3 PUFA intake during the first and third trimester of pregnancy was estimated using validated food frequency questionnaires. Child neuropsychological functions were assessed using Bayley Scales of Infant Development version one (BSID) at 1 year old, the McCarthy Scale of Children’s Abilities (MSCA) at 4 years old, and the Attention Network Test (ANT) at 7 years old. Data were analysed using multivariate linear regression models and adjusted for potential covariates, such as maternal social class, education, cohort location, alcohol consumption, smoking, breastfeeding duration, and energy intake. Results: Compared to participants in the lowest quartile (<1.262 g/week) of n-3 PUFA consumption during the first trimester, those in the highest quartile (>1.657 g/week) had a 2.26 points (95% confidence interval (CI): 0.41, 4.11) higher MSCA general cognitive score, a 2.48 points (95% CI: 0.53, 4.43) higher MSCA verbal score, and a 2.06 points (95% CI: 0.166, 3.95) higher MSCA executive function score, and a 11.52 milliseconds (95% CI:-22.95,-0.09) lower ANT hit reaction time standard error. In the third pregnancy trimester, the associations were weaker. Conclusions: Positive associations between n-3 PUFA intake during early pregnancy and child neuropsychological functions at 4 and 7 years of age were found, and further clinical research is needed to confirm these findings.
    Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: jordi.salas@urv.cat victoria.arija@urv.cat
    Author identifier: 0000-0003-2700-7459 0000-0002-1758-0975
    Record's date: 2024-09-07
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.mdpi.com/2072-6643/14/3/518
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Nutrients. 14 (3):
    APA: Tahaei H; Gignac F; Pinar A; Fernandez-Barrés S; Romaguera D; Vioque J; Santa-Marina L; Subiza-Pérez M; Llop S; Soler-Blasco R; Arija V; Salas-Salvadó (2022). Omega-3 Fatty Acid Intake during Pregnancy and Child Neuropsychological Development: A  ulti-Centre Population-Based Birth Cohort Study in Spain. Nutrients, 14(3), -. DOI: 10.3390/nu14030518
    Article's DOI: 10.3390/nu14030518
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2022
    Publication Type: Journal Publications
  • Keywords:

    Food Science,Nutrition & Dietetics,Nutrition and Dietetics
    Population-based cohort
    Polyunsaturated fatty-acids
    Omega-3 fatty acids
    Neurodevelopment
    Maternal diet
    Children
    seafood
    population-based cohort
    omega-3 fatty acids
    neurodevelopmental outcomes
    neurodevelopment
    energy
    diet
    consumption
    children
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Psicología
    Planejamento urbano e regional / demografia
    Nutrition and dietetics
    Nutrition & dietetics
    Nutrição
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    Food science
    Farmacia
    Engenharias iv
    Engenharias ii
    Enfermagem
    Educação física
    Economia
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Biotecnología
  • Documents:

  • Cerca a google

    Search to google scholar