Author, as appears in the article.: Tresserra-Rimbau A; Castro-Barquero S; Becerra-Tomás N; Babio N; Martínez-González MÁ; Corella D; Fitó M; Romaguera D; Vioque J; Alonso-Gomez AM; Wärnberg J; Martínez JA; Serra-Majem L; Estruch R; Tinahones FJ; Lapetra J; Pintó X; Tur JA; López-Miranda J; Cano-Ibáñez N; Delgado-Rodríguez M; Matía-Martín P; Daimiel L; Sánchez VM; Vidal J; Vázquez C; Ros E; Basterra FJ; de la Puente MF; Asensio EM; Castañer O; Bullón-Vela V; Tojal-Sierra L; Gómez-Gracia E; Cases-Pérez E; Konieczna J; García-Ríos A; Casañas-Quintana T; Bernal-Lopez MR; Santos-Lozano JM; Esteve-Luque V; Bouzas C; Vázquez-Ruiz Z; Palau-Galindo A; Barragan R; Grau ML; Razquín C; Goicolea-Güemez L; Toledo E; Vergaz MV; Lamuela-Raventós RM; Salas-Salvadó J
Department: Bioquímica i Biotecnologia
URV's Author/s: Babio Sánchez, Nancy Elvira / Becerra Tomás, Nerea / Palau Galindo, Antonio / Salas Salvadó, Jorge
Keywords: Phenolic acids Obesity Metabolic syndrome Mediterranean diet Hba1c Glycosylated hemoglobin Glucose Flavonoids Cardiometabolic risk Antioxidants type-2 supplementation prevention phenolic acids obesity metabolic syndrome metaanalysis mediterranean diet hba1c glycosylated hemoglobin glucose flavonoids consumption
Abstract: Previous studies suggested that dietary polyphenols could reduce the incidence and complications of type-2 diabetes (T2D); although the evidence is still limited and inconsistent. This work analyzes whether changing to a diet with a higher polyphenolic content is associated with an improved glucose profile. At baseline, and at 1 year of follow-up visits, 5921 participants (mean age 65.0 ± 4.9, 48.2% women) who had overweight/obesity and metabolic syndrome filled out a vali-dated 143-item semi-quantitative food frequency questionnaire (FFQ), from which polyphenol intakes were calculated. Energy-adjusted total polyphenols and subclasses were categorized in tertiles of changes. Linear mixed-effect models with random intercepts (the recruitment centers) were used to assess associations between changes in polyphenol subclasses intake and 1-year plasma glucose or glycosylated hemoglobin (HbA1c) levels. Increments in total polyphenol intake and some classes were inversely associated with better glucose levels and HbA1c after one year of follow-up. These associations were modified when the analyses were run considering diabetes status separately. To our knowledge, this is the first study to assess the relationship between changes in the intake of all polyphenolic groups and T2D-related parameters in a senior population with T2D or at high-risk of developing T2D.
Thematic Areas: Química Physiology Molecular biology Medicina ii Medicina i Interdisciplinar Food science & technology Food science Farmacia Engenharias ii Clinical biochemistry Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, medicinal Cell biology Biotecnología Biodiversidade Biochemistry & molecular biology Biochemistry
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: antonio.palau@urv.cat nerea.becerra@urv.cat nancy.babio@urv.cat jordi.salas@urv.cat
Author identifier: 0000-0002-4429-6507 0000-0003-3527-5277 0000-0003-2700-7459
Record's date: 2024-01-13
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2076-3921/11/2/316
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Antioxidants. 11 (2):
APA: Tresserra-Rimbau A; Castro-Barquero S; Becerra-Tomás N; Babio N; Martínez-González MÁ; Corella D; Fitó M; Romaguera D; Vioque J; Alonso-Gomez AM; Wärn (2022). Adopting a High-Polyphenolic Diet Is Associated with an Improved Glucose Profile: Prospective Analysis within the PREDIMED-Plus Trial. Antioxidants, 11(2), -. DOI: 10.3390/antiox11020316
Article's DOI: 10.3390/antiox11020316
Entity: Universitat Rovira i Virgili
Journal publication year: 2022
Publication Type: Journal Publications
Repositori URV