Author, as appears in the article.: Arreaza-Gil, Veronica; Escobar-Martinez, Ivan; Suarez, Manuel; Bravo, Francisca Isabel; Muguerza, Begona; Arola-Arnal, Anna; Torres-Fuentes, Cristina;
Department: Bioquímica i Biotecnologia
e-ISSN: 2072-6643
URV's Author/s: Arola Arnal, Anna / Arreaza Gil, Verónica / Bravo Vázquez, Francisca Isabel / Escobar Martínez, Ivan / Muguerza Marquínez, Maria Begoña / Suárez Recio, Manuel / Torres Fuentes, Cristina
Keywords: Seasonal rhythms Photoperiods Obesity Mechanisms Gut microbiota Diet Circadian-rhythm Cafeteria diet Brain axis Adaptation
Abstract: Gut microbiota and biological rhythms are emerging as key factors in the modulation of several physiological and metabolic processes. However, little is known about their interaction and how this may affect host physiology and metabolism. Several studies have shown oscillations of gut microbiota that follows a circadian rhythmicity, but, in contrast, variations due to seasonal rhythms have not been sufficiently investigated yet. Thus, the goal of this study was to investigate the impact of different photoperiods, which mimic seasonal changes, on fecal microbiota composition and how this interaction affects diet-induced obesity development. To this aim, Fisher 344 male rats were housed under three photoperiods (L6, L12 and L18) and fed with standard chow diet or cafeteria diet (CAF) for 9 weeks. The 16S ribosomal sequencing of collected fecal samples was performed. The photoperiod exposure significantly altered the fecal microbiota composition under L18, especially in CAF-fed rats. Moreover, these alterations were associated with changes in body weight gain and different fat parameters. These findings suggest a clear impact of seasonal rhythms on gut microbiota, which ultimately translates into different susceptibilities to diet-induced obesity development. This is the first time to our knowledge that the photoperiod impact on gut microbiota composition has been described in an obesity context although further studies are needed in order to elucidate the mechanisms involved.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: franciscaisabel.bravo@urv.cat cristina.torres@urv.cat begona.muguerza@urv.cat anna.arola@urv.cat manuel.suarez@urv.cat veronica.arreaza@estudiants.urv.cat veronica.arreaza@estudiants.urv.cat ivan.escobar@estudiants.urv.cat
Author identifier: 0000-0002-6468-3088 0000-0002-2917-6910 0000-0001-7384-8588 0000-0001-6529-1345 0000-0003-0122-8253 0000-0002-8301-2095 0000-0002-8301-2095
Record's date: 2024-06-22
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2072-6643/14/3/722
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Nutrients. 14 (3):
APA: Arreaza-Gil, Veronica; Escobar-Martinez, Ivan; Suarez, Manuel; Bravo, Francisca Isabel; Muguerza, Begona; Arola-Arnal, Anna; Torres-Fuentes, Cristina; (2022). Gut Seasons: Photoperiod Effects on Fecal Microbiota in Healthy and Cafeteria-Induced Obese Fisher 344 Rats. Nutrients, 14(3), -. DOI: 10.3390/nu14030722
Article's DOI: 10.3390/nu14030722
Entity: Universitat Rovira i Virgili
Journal publication year: 2022
Publication Type: Journal Publications
Repositori URV