Author, as appears in the article.: Xifre-Perez, Elisabet; Ferre-Borrull, Josep; Marsal, Lluis F
Department: Enginyeria Electrònica, Elèctrica i Automàtica
URV's Author/s: Ferré Borrull, José / Marsal Garví, Luis Francisco / Xifré Pérez, Elisabet
Keywords: Ultrasensitive detection Surface-plasmon resonance Pulse anodization Porous alumina Photonic crystals Oligonucleotides Nanoporous anodic alumina Nanoparticles enhance Immunosensors Health Free optical-detection Free dna biosensor Electrochemical nanobiosensor Distributed-bragg-reflector Biosensors Aptamers Antibodies
Abstract: This paper is an overview of the recent advances in nanoporous anodic alumina sensing platforms based on the interaction of oligonucleotides and antibodies with bioelements (e.g., virus, bacteria, or biomarkers) that can cause or identify diseases. Nanoporous alumina is the common platform material for all these sensing devices that have an enormous potential for the next-generation bioanalytical systems. Nanoporous alumina is a cost-effective material with morphological flexibility that provides high sensitivity to the sensing systems due to its large surface-to-volume ratio. Immunosensors transduce the signal produced by the specific antibody-antigen interaction. They are widely used for clinical analysis due to the high selectivity and sensitivity of their immunoreaction, transduced by different methods (electrochemical, optical, piezoelectric, etc). Another important, outstanding and more recently type of biosensors are based on the oligonucleotic functionalization of nanoporous alumina. Oligonucleotides can bind to a wide variety of elements (small organic molecules, proteins, or cells) with high selectivity, specificity, and affinity, even higher to those of antibodies. The basic concepts and mechanisms of their sensing methods for health care biosensing are introduced. Their transduction methods and great potential applications will be evaluated and classified in detail, together with a discussion of possible future trends.
Thematic Areas: Mechanics of materials Materials science, multidisciplinary Materials science (miscellaneous) Materials science (all) Industrial and manufacturing engineering General materials science
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: josep.ferre@urv.cat elisabet.xifre@urv.cat lluis.marsal@urv.cat
Author identifier: 0000-0002-5210-5133 0000-0001-6072-9889 0000-0002-5976-1408
Record's date: 2024-10-12
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://onlinelibrary.wiley.com/doi/full/10.1002/admt.202101591
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Advanced Materials Technologies. 7 (9): 2101591-
APA: Xifre-Perez, Elisabet; Ferre-Borrull, Josep; Marsal, Lluis F (2022). Oligonucleotic Probes and Immunosensors Based on Nanoporous Anodic Alumina for Screening of Diseases. Advanced Materials Technologies, 7(9), 2101591-. DOI: 10.1002/admt.202101591
Article's DOI: 10.1002/admt.202101591
Entity: Universitat Rovira i Virgili
Journal publication year: 2022
Publication Type: Journal Publications