Author, as appears in the article.: Nunez, Mireia; Fontanals, Nuria; Borrull, Francesc; Marcie, Rosa Maria
Department: Química Analítica i Química Orgànica
URV's Author/s: Borrull Ballarín, Francesc / Fontanals Torroja, Núria / Marcé Recasens, Rosa Maria / NÚÑEZ MARCÉ, MIREIA
Keywords: Risk assessment Pressurised liquid extraction Organophosphate flame retardants Indoor dust Human exposure High production volume chemicals Gas chromatography-mass spectrometry risk assessment pressurised liquid extraction plasticizers phthalate multi-residue method indoor dust human exposure house-dust gas chromatography-mass spectrometry extraction esters barcelona
Abstract: A multiresidue analytical method based on pressurised liquid extraction and gas-chromatography mass spectrometry was developed to determine 22 compounds belonging to different chemical families in indoor dust: seven organophosphate esters, six phthalate esters, three benzotriazoles, five benzothiazoles and four benzenesulfonamides were included in the present study, all of them belonging to the category of high production volume chemicals (HPVCs). Apparent recoveries ranged between 45% and 123% and method quantification limits ranged from 0.03 μg/g to 3.8 μg/g. The occurrence of the selected HPVCs was evaluated in indoor dust from different locations in the Tarragona (Catalonia, Spain) region. Two benzenesulfonamides, ortho-toluenesulfonamide and para-toluenesulfonamide, were detected in dust samples for the first time. Phthalate esters and organophosphate esters were the most abundant compounds found, and di-(2-ethylhexyl) phthalate (DEHP) was determined at the highest concentrations. With the data obtained, human exposure was assessed by calculating the estimated daily intakes (EDI) via ingestion and dermal contact. Non-carcinogenic and carcinogenic risk assessments found no risks in any of the scenarios tested, which included two age classes (children and adults) and two possible exposure scenarios (median and worst-case scenario), except for the evaluation of carcinogen risk due to ingestion of DEHP in the worst-case scenario.Copyright © 2022. Published by Elsevier Ltd.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Public health, environmental and occupational health Pollution Odontología Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Materiais Interdisciplinar Health, toxicology and mutagenesis Geociências General chemistry Farmacia Environmental sciences Environmental engineering Environmental chemistry Ensino Engenharias iii Engenharias ii Engenharias i Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry (miscellaneous) Chemistry (all) Biotecnología Biodiversidade Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: nuria.fontanals@urv.cat nuria.fontanals@urv.cat rosamaria.marce@urv.cat francesc.borrull@urv.cat
Author identifier: 0000-0002-7534-1964 0000-0002-7534-1964 0000-0002-5667-2899 0000-0003-2718-9336
Record's date: 2024-10-12
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.sciencedirect.com/science/article/pii/S0045653522011328
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Chemosphere. 301 134639-134639
APA: Nunez, Mireia; Fontanals, Nuria; Borrull, Francesc; Marcie, Rosa Maria (2022). Multiresidue analytical method for high production volume chemicals in dust samples, occurrence and human exposure assessment. Chemosphere, 301(), 134639-134639. DOI: 10.1016/j.chemosphere.2022.134639
Article's DOI: 10.1016/j.chemosphere.2022.134639
Entity: Universitat Rovira i Virgili
Journal publication year: 2022
Publication Type: Journal Publications
Repositori URV