Author, as appears in the article.: Ibarz-Blanch N; Morales D; Calvo E; Ros-Medina L; Muguerza B; Bravo FI; Suárez M
Department: Bioquímica i Biotecnologia
URV's Author/s: Bravo Vázquez, Francisca Isabel / Calvo Manso, Enrique / Ibarz Blanch, Néstor / Morales Hernández, Diego / Muguerza Marquínez, Maria Begoña / Ros Medina, Laura / Suárez Recio, Manuel
Keywords: Phenolic compounds Peptides I-converting-enzyme Hypertension Blood pressure Biological rhythms vascular function phenolic-compounds phenolic compounds peptides nadph oxidases hypertension endothelial nitric-oxide clock gene per2 circadian clock biological rhythms angiotensin-ii ambulatory blood-pressure ace inhibitory-activity
Abstract: Hypertension (HTN) is one of the main cardiovascular risk factors and is considered a major public health problem. Numerous approaches have been developed to lower blood pressure (BP) in hypertensive patients, most of them involving pharmacological treatments. Within this context, natural bioactive compounds have emerged as a promising alternative to drugs in HTN prevention. This work reviews not only the mechanisms of BP regulation by these antihypertensive compounds, but also their efficacy depending on consumption time. Although a plethora of studies has investigated food-derived compounds, such as phenolic compounds or peptides and their impact on BP, only a few addressed the relevance of time consumption. However, it is known that BP and its main regulatory mechanisms show a 24-h oscillation. Moreover, evidence shows that phenolic compounds can interact with clock genes, which regulate the biological rhythm followed by many physiological processes. Therefore, further research might be carried out to completely elucidate the interactions along the time–nutrition–hypertension axis within the framework of chrononutrition.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: nestor.ibarz@urv.cat enrique.calvo@urv.cat laura.ros@urv.cat nestor.ibarz@urv.cat manuel.suarez@urv.cat franciscaisabel.bravo@urv.cat begona.muguerza@urv.cat
Author identifier: 0000-0003-0122-8253 0000-0002-6468-3088 0000-0001-7384-8588
Record's date: 2024-09-21
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2072-6643/14/9/1920
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Nutrients. 14 (9):
APA: Ibarz-Blanch N; Morales D; Calvo E; Ros-Medina L; Muguerza B; Bravo FI; Suárez M (2022). Role of Chrononutrition in the Antihypertensive Effects of Natural Bioactive Compounds. Nutrients, 14(9), -. DOI: 10.3390/nu14091920
Article's DOI: 10.3390/nu14091920
Entity: Universitat Rovira i Virgili
Journal publication year: 2022
Publication Type: Journal Publications