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Recent chromatographic and electrophoretic based methods for determining drugs of abuse in urine and oral fluid: A review from 2018 to June 2021

  • Identification data

    Identifier: imarina:9266682
    Authors:
    Pascual-Caro SBorrull FCalull MAguilar C
    Abstract:
    Urine and oral fluid are important biological matrices used for forensic and toxicological analyses. These two complementary matrices can be used to provide information about recent and long-term drug consumption. Several analytical methods have been developed in recent years to determine different drugs of abuse in these biological samples. Most of them are based on chromatographic and related techniques, such as liquid chromatography or gas chromatography and capillary electrophoresis. Moreover, as these biological matrices can contain various compounds that may interfere with the analytes of interest, a sample pre-treatment is usually necessary. Different pre-treatment strategies have been carried out, including solid-phase extraction and liquid-liquid extraction, among others. The present review aims to provide a comprehensive overview and a discussion of the latest trends and the most used strategies for determining drugs of abuse in urine and oral fluid samples using chromatographic and electrophoretic techniques between 2018 and June 2021.
  • Others:

    Author, as appears in the article.: Pascual-Caro S; Borrull F; Calull M; Aguilar C
    Department: Química Analítica i Química Orgànica
    URV's Author/s: Aguilar Anguera, Maria del Carmen / Borrull Ballarín, Francesc / Calull Blanch, Marta / Pascual Caro, Sergi
    Keywords: Urine analysis Toxicological and forensic analyses Oral fluid analysis Drugs of abuse Chromatographic and related techniques Amphetamine-type stimulants whole-blood urine analysis toxicological and forensic analyses tandem mass-spectrometry samples psychoactive substances oral fluid analysis methamphetamine matrices high-resolution electrospray-ionization chromatographic and related techniques capillary-electrophoresis
    Abstract: Urine and oral fluid are important biological matrices used for forensic and toxicological analyses. These two complementary matrices can be used to provide information about recent and long-term drug consumption. Several analytical methods have been developed in recent years to determine different drugs of abuse in these biological samples. Most of them are based on chromatographic and related techniques, such as liquid chromatography or gas chromatography and capillary electrophoresis. Moreover, as these biological matrices can contain various compounds that may interfere with the analytes of interest, a sample pre-treatment is usually necessary. Different pre-treatment strategies have been carried out, including solid-phase extraction and liquid-liquid extraction, among others. The present review aims to provide a comprehensive overview and a discussion of the latest trends and the most used strategies for determining drugs of abuse in urine and oral fluid samples using chromatographic and electrophoretic techniques between 2018 and June 2021.
    Thematic Areas: Spectroscopy Química Medicina ii Interdisciplinar Farmacia Environmental chemistry Engenharias iv Engenharias iii Engenharias ii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, analytical Biotecnología Astronomia / física Analytical chemistry
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: sergi.pascual@estudiants.urv.cat carme.aguilar@urv.cat marta.calull@urv.cat francesc.borrull@urv.cat
    Author identifier: 0000-0001-8890-5100 0000-0002-5913-2599 0000-0002-5258-1949 0000-0003-2718-9336
    Record's date: 2024-09-07
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.sciencedirect.com/science/article/pii/S0165993622001881
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Trac-Trends In Analytical Chemistry. 156
    APA: Pascual-Caro S; Borrull F; Calull M; Aguilar C (2022). Recent chromatographic and electrophoretic based methods for determining drugs of abuse in urine and oral fluid: A review from 2018 to June 2021. Trac-Trends In Analytical Chemistry, 156(), -. DOI: 10.1016/j.trac.2022.116705
    Article's DOI: 10.1016/j.trac.2022.116705
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2022
    Publication Type: Journal Publications
  • Keywords:

    Analytical Chemistry,Chemistry, Analytical,Environmental Chemistry,Spectroscopy
    Urine analysis
    Toxicological and forensic analyses
    Oral fluid analysis
    Drugs of abuse
    Chromatographic and related techniques
    Amphetamine-type stimulants
    whole-blood
    urine analysis
    toxicological and forensic analyses
    tandem mass-spectrometry
    samples
    psychoactive substances
    oral fluid analysis
    methamphetamine
    matrices
    high-resolution
    electrospray-ionization
    chromatographic and related techniques
    capillary-electrophoresis
    Spectroscopy
    Química
    Medicina ii
    Interdisciplinar
    Farmacia
    Environmental chemistry
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Chemistry, analytical
    Biotecnología
    Astronomia / física
    Analytical chemistry
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