Author, as appears in the article.: Gomila, A.; Carratala, J.; Biondo, S.; Badia, J. M.; Fraccalvieri, D.; Shaw, E.; Diaz-Brito, V.; Pagespetit, L.; Freixas, N.; Brugues, M.; Mora, L.; Perez, R.; Sanz, C.; Arroyo, N.; Iftimie, S.; Limon, E.; Gudiol, F.; Pujol, M.;VINCat Colon Surg Grp
Department: Medicina i Cirurgia
URV's Author/s: Iftimie Iftimie, Simona Mihaela
Keywords: Ventilator-associated pneumonia Surgical site infection Stoma Risk-factors Rectal-cancer Program Outcomes Nsqip Low anterior resection Impact Healthcare-associated infection Colorectal surgery Colorectal cancer Bowel preparation
Abstract: Background: Surgical site infections (SSIs) are the leading cause of healthcare-associated infections in acute care hospitals in Europe. However, the risk factors for the development of early-onset (EO) and late-onset (LO) SSI have not been elucidated.Aim: This study investigated the predictive factors for EO-SSI and LO-SSI in a large cohort of patients undergoing colorectal surgery.Methods: We prospectively followed-up adult patients undergoing elective colorectal surgery in 10 hospitals (2011-2014). Patients were divided into three groups: EO-SSI, LO-SSI, or no infection (no-SSI). The cut-off defining EO-SSI and LO-SSI was seven days (median time to SSI development). Different predictive factors for EO-SSI and LO-SSI were analysed, comparing each group with the no-SSI patients.Findings: Of 3701 patients, 320 (8.6%) and 349 (9.4%) developed EO-SSI and LO-SSI, respectively. The rest had no-SSI. Patients with EO-SSI were mostly males, had colon surgery and developed organ-space SSI whereas LO-SSI patients frequently received chemotherapy or radiotherapy and had incisional SSI. Male sex (odds ratio (OR): 1.92; P < 0.001), American Society of Anesthesiologists' physical status > 2 (OR: 1.51; P = 0.01), administration of mechanical bowel preparation (OR: 0.7; P = 0.03) and stoma creation (OR: 1.95; P < 0.001) predicted EO-SSI whereas rectal surgery (OR: 1.43; P = 0.03), prolonged surgery (OR: 1.4; P = 0.03) and previous chemotherapy (OR: 1.8; P = 0.03) predicted LO-SSI.Conclusion: We found distinctive predictive factors for the development of SSI before and after seven days following elective colorectal surgery. These factors could help establish specific preventive measures in each group. (C) 2017 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
Thematic Areas: Saúde coletiva Química Public, environmental & occupational health Odontología Microbiology (medical) Medicine (miscellaneous) Medicina iii Medicina ii Medicina i Interdisciplinar Infectious diseases General medicine Farmacia Engenharias iv Enfermagem Educação física Ciências biológicas iii Ciências biológicas i Ciências agrárias i Biotecnología Biodiversidade
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: simonamihaela.iftime@urv.cat
Author identifier: 0000-0003-0714-8414
Record's date: 2024-07-27
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://www.journalofhospitalinfection.com/article/S0195-6701(17)30695-3/fulltext#articleInformation
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Journal Of Hospital Infection. 99 (1): 24-30
APA: Gomila, A.; Carratala, J.; Biondo, S.; Badia, J. M.; Fraccalvieri, D.; Shaw, E.; Diaz-Brito, V.; Pagespetit, L.; Freixas, N.; Brugues, M.; Mora, L.; P (2018). Predictive factors for early- and late-onset surgical site infections in patients undergoing elective colorectal surgery. A multicentre, prospective, cohort study. Journal Of Hospital Infection, 99(1), 24-30. DOI: 10.1016/j.jhin.2017.12.017
Article's DOI: 10.1016/j.jhin.2017.12.017
Entity: Universitat Rovira i Virgili
Journal publication year: 2018
Publication Type: Journal Publications
Repositori URV