Author, as appears in the article.: Adriaenssens L; Acero Sánchez JL; Barril X; O'Sullivan CK; Ballester P
Department: Enginyeria Química
URV's Author/s: ACERO SÁNCHEZ, JOSEP LLUÍS / O'SULLIVAN, CIARA KATHLEEN
Keywords: Pyridine n-oxides
Abstract: Using a commercial instrument that integrates microfluidics with surface plasmon resonance (SPR) detection, we thermodynamically and kinetically characterise the interactions of water-soluble calix[4]pyrroles with surface-immobilized guests derived from pyridine N-oxide. This technique provides detailed information in real time and shows that, while thermodynamically similar, the binding process occurring with the surface-immobilised guests is kinetically very different to that in solution. Two different binding processes can be distinguished for the surface-immobilised guests. Both complexation processes provide 1:1 complexes with thermodynamic stabilities that are similar to each other and to the 1:1 complex formed in solution. However, the kinetic stabilities of the complexes formed with the surface anchored ligands are significantly higher. These observations are rationalized on the basis of the effects exerted by the dextran matrix employed for the ligand's immobilisation on the small molecule complexes that are formed. This journal is © the Partner Organisations 2014.
Thematic Areas: Astronomia / física Chemistry (all) Chemistry (miscellaneous) Chemistry, multidisciplinary Ciências biológicas i Ciências biológicas iii Farmacia General chemistry Interdisciplinar Materiais Química
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: ciara.osullivan@urv.cat
Author identifier: 0000-0002-0965-4655 0000-0003-2603-2230
Record's date: 2022-10-15
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://pubs.rsc.org/en/content/articlelanding/2014/sc/c4sc01745e
Papper original source: Chemical Science. 5 (11): 4210-4215
APA: Adriaenssens L; Acero Sánchez JL; Barril X; O'Sullivan CK; Ballester P (2014). Binding of calix[4]pyrroles to pyridine N-oxides probed with surface plasmon resonance. Chemical Science, 5(11), 4210-4215. DOI: 10.1039/c4sc01745e
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.1039/c4sc01745e
Entity: Universitat Rovira i Virgili
Journal publication year: 2014
Publication Type: Journal Publications