Author, as appears in the article.: Parada-Ricart, Ester; Luque, Veronica; Zaragoza, Marta; Ferre, Natalia; Closa-Monasterolo, Ricardo; Koletzko, Berthold; Grote, Veit; Gruszfeld, Dariusz; Verduci, Elvira; Xhonneux, Annick; Escribano, Joaquin
Department: Medicina i Cirurgia
URV's Author/s: Closa Monasterolo, Ricardo / Escribano Subías, Joaquín / Ferre Pallas, Natalia / Luque Moreno, Verònica / Parada Ricart, Esther / Zaragoza Jordana, Marta
Keywords: Smoking Prenatal exposure delayed effects Pregnancy Pediatric obesity Low-birth-weight Infant Hypertension Humans Female Cohort studies Child Blood pressure tobacco-smoke risk-factors protein prenatal smoking infant formula follow-up exposure associations age
Abstract: Hypertension is a public health issue that can have its origin in the early phases of development. Maternal smoking during pregnancy (MSDP) could play a role in offspring’s cardio-metabolic programming. To assess the relationship between MSDP and later blood pressure (BP) in children we conducted a secondary analysis of a randomized dietary intervention trial (EU-Childhood Obesity Project). Healthy term infants with normal birth weight were recruited during the first 8 weeks of life in 5 European countries and followed until 11 years of age. Data on MSDP was collected at recruitment. BP and anthropometry were assessed at 11 years of age. Children were classified according to AAP guidelines as normal BP: BP < 90th percentile; high BP: ≥ 90th percentile with the subset of children having BP > 95th percentile categorized as hypertensive. Out of 572 children, 20% were exposed to MSDP. At 11 years, 26.8% had BP over the 90th centile. MSDP beyond 12 weeks of gestation was associated with higher systolic BP percentile (adjusted B 6.935; 95% CI 0.454, 13.429; p = 0.036) and over twofold increase likelihood of hypertension (OR 2.195; 95% CI 1.089, 4.423; p = 0.028) in children at 11 years. MSDP was significantly associated with later BP in children.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Odontología Nutrição Multidisciplinary sciences Multidisciplinary Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Letras / linguística Interdisciplinar Geografía Geociências Farmacia Engenharias iv Engenharias iii Engenharias ii Enfermagem Educação física Educação Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Biotecnología Biodiversidade Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: esther.parada@urv.cat marta.zaragoza@urv.cat marta.zaragoza@urv.cat ricardo.closa@urv.cat veronica.luque@urv.cat natalia.ferre@urv.cat joaquin.escribano@urv.cat
Author identifier: 0000-0002-9963-4163 0000-0003-2615-8175 0000-0002-2838-1525 0000-0002-5041-459X
Record's date: 2025-03-03
Paper version: info:eu-repo/semantics/publishedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Paper original source: Scientific Reports. 12 (1): 17308-
APA: Parada-Ricart, Ester; Luque, Veronica; Zaragoza, Marta; Ferre, Natalia; Closa-Monasterolo, Ricardo; Koletzko, Berthold; Grote, Veit; Gruszfeld, Darius (2022). Effect of maternal smoking during pregnancy on child blood pressure in a European cohort. Scientific Reports, 12(1), 17308-. DOI: 10.1038/s41598-022-21337-7
Entity: Universitat Rovira i Virgili
Journal publication year: 2022
Publication Type: Journal Publications
Repositori URV