Author, as appears in the article.: Tsilidis, Konstantinos K.; Cariolou, Margarita; Becerra-Tomas, Nerea; Balducci, Katia; Vieira, Rita; Abar, Leila; Aune, Dagfinn; Markozannes, Georgios; Nanu, Neesha; Greenwood, Darren C.; Giovannucci, Edward L.; Gunter, Marc J.; Jackson, Alan A.; Kampman, Ellen; Lund, Vivien; Allen, Kate; Brockton, Nigel T.; Croker, Helen; Katsikioti, Daphne; McGinley-Gieser, Deirdre; Mitrou, Panagiota; Wiseman, Martin; Cross, Amanda J.; Riboli, Elio; Clinton, Steven K.; McTiernan, Anne; Norat, Teresa; Chan, Doris S. M.;
Department: Bioquímica i Biotecnologia
URV's Author/s: Becerra Tomás, Nerea
Keywords: Survival Soy food-intake Recurrence Physical activity Metaanalysis Evidence grading Diet Breast cancer survival Body fatness
Abstract: Based on the Global Cancer Update Programme, formally known as the World Cancer Research Fund/American Institute for Cancer Research Continuous Update Project, we performed systematic reviews and meta-analyses to investigate the association of postdiagnosis body fatness, physical activity and dietary factors with breast cancer prognosis. We searched PubMed and Embase for randomised controlled trials and longitudinal observational studies from inception to 31 October 2021. We calculated summary relative risks (RRs) and 95% confidence intervals (CIs) using random-effects meta-analyses. An independent Expert Panel graded the quality of evidence according to predefined criteria. The evidence on postdiagnosis body fatness and higher all-cause mortality (RR per 5 kg/m(2) in body mass index: 1.07, 95% CI: 1.05-1.10), breast cancer-specific mortality (RR: 1.10, 95% CI: 1.06-1.14) and second primary breast cancer (RR: 1.14, 95% CI: 1.04-1.26) was graded as strong (likelihood of causality: probable). The evidence for body fatness and breast cancer recurrence and other nonbreast cancer-related mortality was graded as limited (likelihood of causality: limited-suggestive). The evidence on recreational physical activity and lower risk of all-cause (RR per 10 metabolic equivalent of task-hour/week: 0.85, 95% CI: 0.78-0.92) and breast cancer-specific mortality (RR: 0.86, 95% CI: 0.77-0.96) was judged as limited-suggestive. Data on dietary factors was limited, and no conclusions could be reached except for healthy dietary patterns, isoflavone and dietary fibre intake and serum 25(OH)D concentrations that were graded with limited-suggestive evidence for lower risk of the examined outcomes. Our results encourage the development of lifestyle recommendations for breast cancer patients to avoid obesity and be physically active.
Thematic Areas: Saúde coletiva Química Oncology Odontología Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Cancer research Biotecnología Biodiversidade
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: nerea.becerra@urv.cat
Author identifier: 0000-0002-4429-6507
Record's date: 2024-08-03
Papper version: info:eu-repo/semantics/publishedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: International Journal Of Cancer. 152 (4): 635-644
APA: Tsilidis, Konstantinos K.; Cariolou, Margarita; Becerra-Tomas, Nerea; Balducci, Katia; Vieira, Rita; Abar, Leila; Aune, Dagfinn; Markozannes, Georgios (2023). Postdiagnosis body fatness, recreational physical activity, dietary factors and breast cancer prognosis: Global Cancer Update Programme (CUP Global) summary of evidence grading. International Journal Of Cancer, 152(4), 635-644. DOI: 10.1002/ijc.34320
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications
Repositori URV