Author, as appears in the article.: Ruiz de Azua MJ; Manocchio F; Cruz-Carrión Á; Arola-Arnal A; Torres-Fuentes C; Bernal CA; Saín J; Suarez M
Department: Bioquímica i Biotecnologia
URV's Author/s: Arola Arnal, Anna / Cruz Carrión, Álvaro Javier / Suárez Recio, Manuel / Torres Fuentes, Cristina
Keywords: Skeletal-muscle Seasonality Metabolism Fatty acid profile Chrononutrition seasonality rhythms physiology oxidation metabolism lipid-metabolism light fatty acid profile circadian clock cells
Abstract: Circadian and seasonal variations produce variations in physiological processes throughout the day and the year, respectively. In this sense, both the light and the moment of feeding are strong modulators of the central and peripheral clocks. However, little is known about its influence on certain metabolic parameters and on the composition of liver and muscle fatty acids (FA). In the present study, 24 Fischer 344 rats were exposed for 11 weeks to different photoperiods, L6, L12 and L18, with 6, 12 and 18 h of light/day, respectively. They were fed a standard diet. Serum metabolic parameters, gene expression of liver enzymes and gastrocnemius muscle involved in the synthesis, elongation, desaturation and β-oxidation of FA were analyzed. We have found that exposure to different hours of light has a clear effect on FA composition and gene expression in the liver. Mainly, the biosynthesis of unsaturated FA was altered in the L18 animals with respect to those exposed to L12, while the L6 did not show significant changes. At the muscle level, differences were observed in the concentration of mono and polyunsaturated FA. A multivariate analysis confirmed the differences between L12 and L18 in a significant way. We conclude that exposure to long days produces changes in the composition of liver and muscle FA, as well as changes in the gene expression of oxidative enzymes compared to exposure to L12, which could be a consequence of different seasonal eating patterns.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Radiology, nuclear medicine and imaging Radiological and ultrasound technology Radiation Química Odontología Nutrição Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Biotecnología Biophysics Biodiversidade Biochemistry & molecular biology Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: cristina.torres@urv.cat anna.arola@urv.cat manuel.suarez@urv.cat
Author identifier: 0000-0002-2917-6910 0000-0001-6529-1345 0000-0003-0122-8253
Record's date: 2023-12-16
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.sciencedirect.com/science/article/pii/S1011134422002366
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Journal Of Photochemistry And Photobiology B-Biology. 238 112621-
APA: Ruiz de Azua MJ; Manocchio F; Cruz-Carrión Á; Arola-Arnal A; Torres-Fuentes C; Bernal CA; Saín J; Suarez M (2023). Fatty acid metabolism in liver and muscle is strongly modulated by photoperiod in Fischer 344 rats. Journal Of Photochemistry And Photobiology B-Biology, 238(), 112621-. DOI: 10.1016/j.jphotobiol.2022.112621
Article's DOI: 10.1016/j.jphotobiol.2022.112621
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications
Repositori URV