Author, as appears in the article.: Navarro-Masip, E; Caron, A; Mulero, M; Arola, L; Aragonès, G
Department: Bioquímica i Biotecnologia
URV's Author/s: Aragonès Bargalló, Gerard / Arola Ferrer, Luis Maria / Mulero Abellán, Miguel / Navarro Masip, Èlia
Keywords: Seasonality Photoperiod Obesity Melatonin Male siberian hamster Leptin Adipose tissue tissue seasonality photoperiod phodopus-sungorus obesity neuropeptide-y melatonin leptin sensitivity leptin gene-expression food-intake circadian-rhythms body-weight arcuate nucleus
Abstract: Energy homeostasis and metabolism in mammals are strongly influenced by seasonal changes. Variations in photoperiod patterns drive adaptations in body weight and adiposity, reflecting changes in the regulation of food intake and energy expenditure. Humans also show distinct patterns of energy balance depending on the season, being more susceptible to gaining weight during a specific time of the year. Changes in body weight are mainly reflected by the adipose tissue, which is a key metabolic tissue and is highly affected by circannual rhythms. Mostly, in summer-like (long-active) photoperiod, adipocytes adopt a rather anabolic profile, more predisposed to store energy, while food intake increases and energy expenditure is reduced. These metabolic adaptations involve molecular modifications, some of which have been studied during the last years and are summarized in this review. In addition, there is a bidirectional relation between obesity and the seasonal responses, with obesity disrupting some of the seasonal responses observed in healthy mammals, and altered seasonality being highly associated with increased risk of developing obesity. This suggests that changes in photoperiod produce important metabolic alterations in healthy organisms. Biological rhythms impact the regulation of metabolism to different extents, some of which are already known, but further research is needed to fully understand the relationship between energy balance and seasonality.
Thematic Areas: Zootecnia / recursos pesqueiros Spectroscopy Saúde coletiva Química Psicología Physical and theoretical chemistry Organic chemistry Odontología Nutrição Molecular biology Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Inorganic chemistry Geociências Farmacia Engenharias iv Engenharias ii Engenharias i Educação física Computer science applications Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Chemistry, multidisciplinary Catalysis Biotecnología Biodiversidade Biochemistry & molecular biology Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: lluis.arola@urv.cat gerard.aragones@urv.cat miquel.mulero@urv.cat elia.navarro@estudiants.urv.cat elia.navarro@estudiants.urv.cat
Author identifier: 0000-0003-2767-1974
Record's date: 2024-03-03
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/1422-0067/24/2/1008
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: International Journal Of Molecular Sciences. 24 (2): 1008-
APA: Navarro-Masip, E; Caron, A; Mulero, M; Arola, L; Aragonès, G (2023). Photoperiodic Remodeling of Adiposity and Energy Metabolism in Non-Human Mammals. International Journal Of Molecular Sciences, 24(2), 1008-. DOI: 10.3390/ijms24021008
Article's DOI: 10.3390/ijms24021008
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications
Repositori URV