Author, as appears in the article.: Ochoa-Gondar, Olga; Gomez-Bertomeu, Frederic; Vila-Corcoles, Angel; Raga, Xavier; Aguirre, Carlos; Utrera, Jesus; de Diego, Cinta; Guzman, Jorge A.; Figuerola, Enric;Grp Estudio EPIVAC
Department: Ciències Mèdiques Bàsiques
URV's Author/s: Figuerola Massana, Enric / Gomez Bertomeu, Frederic-Francesc
Keywords: Temporal trends Nonvaccine serotypes Navarre Increase Impact Epidemiology Conjugate vaccine Children Catalonia Age
Abstract: Background. Pneumococcal infections remain a major health problem worldwide. This study analysed the distribution of distinct Streptococcus pneumoniae serotypes causing invasive pneumococcal disease (IPD) among all-age population in the region of Tarragona (Spain) throughout 2006-2009.Methods. An amount of 237 strains were evaluated, of which 203 (85.7%) were isolated from blood cultures, 14 (5.9%) from pleural fluids, 13 (5.5%) from CSF samples and 7 (3%) from other sterile sites. Forty-seven cases (19.8%) were children <= 14 years, 94 (39.7%) were patients 15-64 years and 96 (40.5%) were patients >= 65 years.Results. Seven serotypes (1, 3, 6A, 7F, 12F, 14 and 19A) caused almost two thirds (63.3%) of cases among all-age patients. Serotype 1 was the most common serotype among children (44.7%) and among people 15-64 years (21.3%), whereas serotype 19A was the most common among people >= 65 years (12.5%). Among all-age population, serotype-vaccine coverage for the distinct pneumococcal polysaccharide vaccine (PPV) and conjugate vaccines (PCVs) were 17.3% for the PCV7, 49.8% for the PCV10, 73% for the PCV13 and 80.2% for the PPV23 (p<0.001). Among children, vaccine-serotype coverage was 23.4% for the PCV7, 72.3% for the PCV10 and 83% for the PCV13. Among people >= 65 years, vaccine-serotype coverage was 62.5% for the PCV13 and 68.8% for the PPV23.Conclusion. A considerable proportion of IPD cases among our population would not be covered by the current pneumococcal vaccines.
Thematic Areas: Pharmacology & pharmacy Pharmacology Oncology Microbiology (medical) Microbiology Medicine (miscellaneous) General medicine
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: enric.figuerola@urv.cat frederic-francesc.gomez@urv.cat
Author identifier: 0000-0002-8039-2889
Record's date: 2023-07-31
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://seq.es/wp-content/uploads/2015/02/seq_0214-3429_28_1_caballero.pdf
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Revista Espanola De Quimioterapia. 28 (1): 29-35
APA: Ochoa-Gondar, Olga; Gomez-Bertomeu, Frederic; Vila-Corcoles, Angel; Raga, Xavier; Aguirre, Carlos; Utrera, Jesus; de Diego, Cinta; Guzman, Jorge A.; F (2015). Prevalence of serotypes causing invasive pneumococcal disease in the region of Tarragona, Spain, 2006-2009: vaccine-serotype coverage for the distinct antipneumococcal vaccine formulations. Revista Espanola De Quimioterapia, 28(1), 29-35
Entity: Universitat Rovira i Virgili
Journal publication year: 2015
Publication Type: Journal Publications
Repositori URV