Articles producció científica> Ciències Mèdiques Bàsiques

Randomised clinical trial to test the phenolization in sacrococcygeal pilonidal disease

  • Identification data

    Identifier: imarina:9291701
    Authors:
    Lopez, JEPerez, JEMallafre, RSVillaro, FFTarrago, ACPerez, BESerafini, JFMartin, RJ
    Abstract:
    To test the efficacy and safety of phenolization in uncomplicated Sacrococcygeal pilonidal disease (SPD) the phenolization in uncomplicated SPD is feasible and secure in selected patients in observational studies. The greatest benefits are obtained to reduce the length of sick leave (LSL) and complications. Single-center randomised controlled clinical trial. Patients were recruited at University Hospital of Tarragona Joan XXIII of Spain. Patients were randomised into two treatment groups. All patients with uncomplicated sacrococcygeal disease, localised in the midline and with only 1 fistulous orifice. The patients were randomly assigned to the phenolization group (PhG) or conventional-surgery group (CsG). Both groups were managed without admission. The main endpoint was the recurrence of sacrococcygeal disease. Secondary endpoints included time of sick leave, complications, and readmission. 124 patients were included in the study. No disease recurrence was observed in either group. Clinical follow-up was carried out with a mean of 493.8 days (SD 6.59). The LSL was shorter in the PhG (mean 19.63 days, SD 28.15) than in the CSG (43.95 days, SD 38.60). The LSL reduction was −24.31 days (P.002). The phenolization in selected SPD is a safe and feasible procedure in selected patients. This approach could become the standard of care for patients with selected Sacrococcygeal pilonidal.
  • Others:

    Author, as appears in the article.: Lopez, JE; Perez, JE; Mallafre, RS; Villaro, FF; Tarrago, AC; Perez, BE; Serafini, JF; Martin, RJ
    Department: Ciències Mèdiques Bàsiques
    URV's Author/s: Elvira Lopez, Jordi / Escuder Pérez, Jorge / Feliu Villaró, Francesc / Jorba Martin, Rosa Maria / Sales Mallafré, Ricard
    Keywords: Sinus disease Sacrococcygeal fistula pilonidal sinus Pilonidal disease of natal cleft Pilonidal disease Phenolization Phenol sacrococcygeal fistula pilonidal sinus risk pilonidal disease of natal cleft pilonidal disease phenolization phenol classification
    Abstract: To test the efficacy and safety of phenolization in uncomplicated Sacrococcygeal pilonidal disease (SPD) the phenolization in uncomplicated SPD is feasible and secure in selected patients in observational studies. The greatest benefits are obtained to reduce the length of sick leave (LSL) and complications. Single-center randomised controlled clinical trial. Patients were recruited at University Hospital of Tarragona Joan XXIII of Spain. Patients were randomised into two treatment groups. All patients with uncomplicated sacrococcygeal disease, localised in the midline and with only 1 fistulous orifice. The patients were randomly assigned to the phenolization group (PhG) or conventional-surgery group (CsG). Both groups were managed without admission. The main endpoint was the recurrence of sacrococcygeal disease. Secondary endpoints included time of sick leave, complications, and readmission. 124 patients were included in the study. No disease recurrence was observed in either group. Clinical follow-up was carried out with a mean of 493.8 days (SD 6.59). The LSL was shorter in the PhG (mean 19.63 days, SD 28.15) than in the CSG (43.95 days, SD 38.60). The LSL reduction was −24.31 days (P.002). The phenolization in selected SPD is a safe and feasible procedure in selected patients. This approach could become the standard of care for patients with selected Sacrococcygeal pilonidal.
    Thematic Areas: Surgery Odontología Medicina iii Medicina ii Medicina i Interdisciplinar Farmacia Educação física Dermatology Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Biotecnología
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: ricard.sales@urv.cat jordi.elvira@urv.cat francesc.feliu@urv.cat jorge.escuder@urv.cat ricard.sales@urv.cat jordi.elvira@urv.cat rosamaria.jorba@urv.cat
    Author identifier: 0000-0003-1700-9813 0000-0003-1700-9813 0000-0003-3307-4340
    Record's date: 2024-08-03
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://onlinelibrary.wiley.com/doi/10.1111/iwj.14096
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: International Wound Journal. 20 (6): 2181-2189
    APA: Lopez, JE; Perez, JE; Mallafre, RS; Villaro, FF; Tarrago, AC; Perez, BE; Serafini, JF; Martin, RJ (2023). Randomised clinical trial to test the phenolization in sacrococcygeal pilonidal disease. International Wound Journal, 20(6), 2181-2189. DOI: 10.1111/iwj.14096
    Article's DOI: 10.1111/iwj.14096
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2023
    Publication Type: Journal Publications
  • Keywords:

    Dermatology,Surgery
    Sinus disease
    Sacrococcygeal fistula pilonidal sinus
    Pilonidal disease of natal cleft
    Pilonidal disease
    Phenolization
    Phenol
    sacrococcygeal fistula pilonidal sinus
    risk
    pilonidal disease of natal cleft
    pilonidal disease
    phenolization
    phenol
    classification
    Surgery
    Odontología
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    Farmacia
    Educação física
    Dermatology
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Biotecnología
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